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Production of Interleukin-2 and Natural Killer (NK) Activity in Patients with Multiple Myeloma

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Gene Technology

Part of the book series: NATO ASI Series ((ASIH,volume 94))

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Abstract

Multiple myeloma (MM) is a clonal lymphoprolipherative disease. Survival ranges from a few months to many years (Kyle, 1988). At least, two factors determine the course of the disease: 1. the biology of malignant cells, 2. the interaction of malignant cells with the host organism,(Joshua, 1988). We have investigated the function of peripheral blood mononuclear cells (PBMC) in patients with different courses of MM in order to determine their prognostic significance in the progression of the disease.

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Author information

Authors and Affiliations

  1. Bone Marrow Transplantation Department, St.Petersburg Center for Advanced Medical Technologes, 197042, St.Petersburg, Russia

    E. Podoltseva

  2. Petrov Research Institute of Oncology, 189646, St.Petersburg, Russia

    E. Morozova

Authors
  1. E. Podoltseva
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  2. E. Morozova
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Editor information

Editors and Affiliations

  1. Universitätskrankenhaus Eppendorf, Martinistraße 52, D-20246, Hamburg, Germany

    Axel R. Zander

  2. Heinrich-Pette-lnstitut für Experimentelle Virologie und Immunologie, Universität Hamburg, Martinistraße 52, D-20246, Hamburg, Germany

    Wolfram Ostertag

  3. City Center for Advanced Medical Technologies, Bone Marrow Transplantation Center, Pr. Dynamo 3, 197042, St.Petersburg, Russia

    Boris V. Afanasiev

  4. Laboratory for Gene Structure Expression, Medical Research Council Institute, The Ridgeway, Mill Hill, London, NW71AA, UK

    Frank Grosveld

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© 1996 Springer-Verlag Berlin Heidelberg

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Podoltseva, E., Morozova, E. (1996). Production of Interleukin-2 and Natural Killer (NK) Activity in Patients with Multiple Myeloma. In: Zander, A.R., Ostertag, W., Afanasiev, B.V., Grosveld, F. (eds) Gene Technology. NATO ASI Series, vol 94. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61122-3_34

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  • DOI: https://doi.org/10.1007/978-3-642-61122-3_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64704-8

  • Online ISBN: 978-3-642-61122-3

  • eBook Packages: Springer Book Archive

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