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Analgesic Hepatopathy

  • Chapter
Drug-Induced Hepatotoxicity

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 121))

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Abstract

Analgesic hepatopathy refers to a spectrum of drug-induced hepatic injury that may be caused by a large number and variety of both prescription and nonprescription drugs. Data on the epidemiology, pathogenesis. clinical manifestations and outcome, treatment, and prevention of hepatic injury due to acetaminophen, the nonsteroidal antiinflammatory drugs (NSAIDs). and narcotic analgesics are reviewed.

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Authors
  1. M. J. Zuckerman
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  2. S. Anuras
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Editor information

Editors and Affiliations

  1. Department of Pathology Division of Experimental Pathology, University of Toronto, Medical Sciences Building, 1 King’s College Circle, M5S 1A8, Toronto, Ontario, Canada

    Ross G. Cameron M.D., Ph.D.

  2. Department of Clinical Biochemistry Banting Institute, University of Toronto, Room 521, 100 College Street, M5G 1L5, Toronto, Ontario, Canada

    George Feuer Ph.D.

  3. Parke-Davis Pharmaceutical Research Division Department of Pathology and Experimental Toxicology, Warner Lambert Company, 2800 Plymouth Road, 48105, Ann Arbor, MI, USA

    Felix A. de la Iglesia M.D.

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Zuckerman, M.J., Anuras, S. (1997). Analgesic Hepatopathy. In: Cameron, R.G., Feuer, G., de la Iglesia, F.A. (eds) Drug-Induced Hepatotoxicity. Handbook of Experimental Pharmacology, vol 121. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61013-4_22

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  • DOI: https://doi.org/10.1007/978-3-642-61013-4_22

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