Abstract
Antipsychotic drugs are prescribed for adults to decrease the psychotic symptoms associated with schizophrenia and affective disorders. Psychosis is rare in childhood, however, and antipsychotics have been prescribed for children primarily to treat other symptoms such as severe overactivity, aggressivity towards self or others, social withdrawal, tics, and stereotypies. These symptoms are associated with a variety of neuropsychiatric disorders of childhood onset. Ideally, an antipsychotic medication will not only decrease troublesome symptoms, but by doing so will also promote the child‚s intellectual, emotional, and social development. However, some of the side effects of neuroleptics can interfere with such growth and development. The physician should weigh the risks and benefits of neuroleptic treatment and, if treatment is begun, carefully titrate the dose (Campbell 1985). This chapter will focus on the double-blind, placebo-controlled studies of antipsychotics in children and adolescents, as well as on some significant case reports.
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Brodkin, E.S., McDougle, C.J., Leckman, J.F. (1996). Antipsychotic Drugs in Children and Adolescents. In: Csernansky, J.G. (eds) Antipsychotics. Handbook of Experimental Pharmacology, vol 120. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-61007-3_16
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DOI: https://doi.org/10.1007/978-3-642-61007-3_16
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