Abstract
All living organisms live in the tension between constancy and change. On the one hand, they have to keep certain structural and functional states reasonably invariant; for instance, concentrations of important ions in the blood plasma (e.g., protons, ionized Ca2+) are maintained within narrow limits by complex regulatory mechanisms establishing homeostatic conditions. On the other hand, many internal and external variables can and must be changed. These changes may depend upon circumstantial requirements, such as the increase in cardiac output and blood pressure during exercise, or they may follow rhythmic patterns, such as diurnal or other periodicity. An important task for the organism then is to coordinate and integrate these different patterns into a functional whole.
Dedicated to the memory of our late colleague H.P. Koepchen
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Windhorst, U. (1996). Regulatory Principles in Physiology. In: Greger, R., Windhorst, U. (eds) Comprehensive Human Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60946-6_2
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DOI: https://doi.org/10.1007/978-3-642-60946-6_2
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