Zusammenfassung
Die therapeutische Wirksamkeit eines Arzneimittels gilt als erwiesen, wenn Scine erwünschten pharmakodynamischen Effekte in einem sinnvollen und kalkulierbaren Verhältnis zu den möglichen unerwünschten Wirkungen stehen. Erst der Nachweis einer günstigen Beeinflussung des Krankheitsverlaufes macht das Medikament zum Werkzeug einer rationalen Arzneimitteltherapie.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Anderson RJ, Schlier RW (1988) Acute tubulär necrosis. In: (Hrsg) Schrier RW, Gottschalk CW. Diseases of the kidney. Little, Brown, Boston, S 1413–1446
Aperia A, Bertorello A, Seri I (1987) Dopamine causes Inhibition of Na, IC-ATPase activity in rat proximal convoluted tubule segments. Am J Physiol 252:F39–F45
Baines AD, Drangova R (1984) Dopamine production by the isolated perfused rat kidney. Can J Physiol Pharmacol 62:272–276
Baldwin L, Henderson A, Hickman P (1994) Effect of postoperative lowdose dopamine on renal function after elective major vascular surgery. Ann Intern Med 120:744–747
Ball SG, Gunn IG, Douglas IH (1982) Renal handling of dopa, dopamine, norepinephrine, and epinephrine in the dog. Am J Physiol 242:F56-F62
Barger G, Ewins AJ (1910) Some phenolic derivatives of Phenylalanine. J Chem Soc 97:2263–2261
Bartholini G, Zivkovic B, Scatton B (1989) Dopaminergic neurons: basic aspects. In: Trendelenburg U, Weiner N (Hrsg) Handbook of Experimental Pharmacology: Catecholamines II. Springer, Berlin Heidelberg New York, S 277–318
Chertow GM, Lazarus JM, Sayegh MH, Allgren RL (1995) Is the administration of dopamine associated with adverse outcomes in severe renal failure? J Am Soc Nephrol 6:460 (Abstract)
Costa P, Ottino GM, Matani A, Pansini S, Canavese C, Passerini G, Grezzana G (1990) Low-dose dopamine during cardiopulmonary bypass in patients with renal dysfunction. J Cardiothor Anesth 4:469–473
Dasta JF, Kirby MG (1986) Pharmacology and therapeutic use of low-dose dopamine. Pharmacotherapy 6:304–310
Felder CC, Campbell T, Albrecht F, Jose PA (1990) Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by Stimulation of adenylate cyclase. Am J Physiol 259:F297-F303
Flancbaum L, Choban PS, Dasta JF (1994) Quantitative effects of low-dose dopamine on urine Output in Oligurie surgical intensive care unit patients. Crit Care Med 22:61–68
Giraud GD, Maannell KL (1984) Decreased nutrient blood flow during dopamine- and epinephrine-induced intestinal vasodilation. J Pharmacol Exp Ther 230:214–220
Goldberg LI, Kohli JD (1983) Peripheral dopamine reeeptors: A Classification based on potency series and specific antagonism. Trends Pharmacol Sci 4 (2): 64–66
Greene SI, Smith JW. (1976) Dopamine gangrene. N Engl J Med 294: 114
Hayashi M, Yamaji Y, Kitajima W, Saruta T (1990) Aromatic L-amino acid decarboxylase activity along the rat nephron. Am J Physiol 258:F28-F33
Hilberman M, Maseda J, Stinson EB, Derby GC, Spencer RJ, Miller DC, Oyer PE, Myers BD (1984) The diuretic properties of dopamine in patients after open-heart Operation. Anesthesiology 61: 489–494
Hoffman BB, Lefkowitz RJ (1990) Catecholamines and sympathomimetic drugs. In: Gilman AG, Rall TW, Nies AS, Taylor P (Hrsg) The pharmacological basis of therapeutics. Pergamon Press, New York, S 187–220
Holtz P, Credner K (1942) Die enzymatische Entstehung von Oxytyramin im Organismus und die physiologische Bedeutung der Dopadecarboxylase. Naunyn-Schmiedeberg’s Arch Pharmacol 200: 356–388
Itskovitz HD, Chen YH, Stier CTJ (1988) Reciprocal renal effects of dopamine and 5-hydroxytryptamine formed within the rat kidney. Clin Sci 75: 503–507
Kebabian JW, Calne DB (1979) Multiple reeeptors for dopamine. Nature 277:93–96
Kleinknecht D (1992) Management of acute renal failure. In: Cameron S, Davison AM, Grünfeld JP, Kerr D, Ritz E (Hrsg) Oxford Textbook of Clinical Nephrology. Oxford Medical Publications, Oxford, S 1015–1026
Le Corre P, Malledant Y, Tanguy M, Le Verge R (1993) Steady-state pharmacokinetics of dopamine in adult patients. Crit Care Med 21:1652–1657
Lee MR. (1993) Dopamine and the kidney: 10 years on. Clin Sci 84:357–375
Lokhandwala MF, Amenta F (1991) Anatomical distribution and function of dopamine reeeptors in the kidney. FASEB J 5:3023–3030
Mannich C, Jacobsohn W (1910) Über Oxyphenylalkylamine und Diophenylalkylamine. Ber Dtsch Chem Ges 43:189–193
Marik PE, Mohedin M (1994) The contrasting effects of dopamine and norepinephrine on systemic and splanchnic oxygen utilization in hyperdynamic sepsis. JAMA 272:1354–1357
Memoli B, Libetta C, Conte G, Andreucci VE (1994) Loop diuretics and renal vasodilators in acute renal failure. Nephrol Dial Transplant 9 Suppl 4: 168–171
Meyer MB, May JL, Goldberg LI (1967) Effects of dopamine on renal function and hemodynamics in the dog. J Pharmacol Exp Ther 156: 186–192
Mühlbauer B, Hartenburg E, Osswald H (1994) Renal response to amino acid infusion in rats: effect of dopamine receptor antagonists and benserazide. Naunyn-Schmiedeberg’s Arch Pharmacol 349: 244–249
Mühlbauer B, Osswald H (1992) Feeding but not salt loading is the dominant factor Controlling urinary dopamine excretion in conscious rats. Naunyn-Schmiedeberg’s Arch Pharmacol 346:469–471
Mühlbauer B, Osswald H (1994) Feeding-induced increase in urinary dopamine excretion is independent of renal innervation and sodium intake. Am J Physiol 266:F563-F567
Myles PS, Buckland MR, Schenk NJ, Cannon GB, Langley M, Davis BB, Weeks AM (1993) Effect of „renal-dose“ dopamine on renal function following cardiac surgery. Anaesth Intensive Care 21: 56–61
Orme ML, Breckenridge A, Dollery CT (1973) The effects of long term administration of dopamine on renal function in hypertensive patients. Eur J Clin Pharmacol 6:150–155
Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Goldblatt E, Pescetti J (1987) Dopamine pharmacokinetics in critically ill newborn infants. J Pediatr 110:293–298
Parks RW, Diamond T, Mrory DC, Johnston GW, Rowlands BJ (1994) Prospective study of postoperative renal function in obstructive jaundice and the effect of perioperative dopamine. Br J Surg 81:437–439
Petrides PE (1990) Nervengewebe. In: Löffier G, Petrides P (Hrsg) Physiologische Chemie. Springer, Berlin Heidelberg New York, S 909–926
Polson RJ, Park GR, Lindop MJ, Farman JV, Calne RY, Williams R (1987) The prevention of renal impairment in patients undergoing orthotopic liver grafting by infusion of low dose dopamine. Anaesthesia 42:15–19
Puschett JB, Winaver J (1992) Effects of diuretics on renal function. In: Windhager EE (Hrsg) Handbook of Physiology (8): Renal Physiology. Oxford University Press, New York, S 2335–2406
Ratcliffe PJ (1992) Pathophysiology of acute renal failure. In: Cameron S, Davison AM, Grünfeld JP, Kerr D, Ritz E (Hrsg) Oxford Textbook of Clinical Nephrology. Oxford University Press, Oxford, S 982–1005
Reinsberg J, Kulimann R (1986) Characterization of vascular dopamine receptors in the gastric circulation of the rabbit. J Cardiovasc Pharmacol 8: 1067–1073
Rump LC, Schwertfeger E, Schuster MJ, Schaible U, Frankenschmidt A, Schollmeyer PJ (1993) Dopamine DA2-receptor activation inhibits noradrenaline release in human kidney slices. Kidney Int 43:197–204
Schwartz LB, Gewertz BL. (1988) The renal response to low dose dopamine. J Surg Res 45: 574–588
Seeman P (1980) Brain dopamine receptors. Pharmacol Rev 32: 229–313
Seeman P, Van Toi HH (1994) Dopamine receptor pharmacology. Trends Pharmacol Sci 15:264–270
Sumikawa K, Hayashi Y, Yamatodani A, Yoshiya I. (1991) Contribution of the lungs to the clearance of exogenous dopamine in humans. Anesth Anaig 72:622–626
Swygert TH, Roberts LC, Valek TR, Brajtbord D, Brown MR, Gunning TC, Paulsen AW, Ramsay MA (1991) Effect of intraoperative low-dose dopamine on renal function in liver transplant reeipients. Anesthesiology 75:571–576
Thompson BT, Cockrill BA. (1994) Renal-dose dopamine: a siren song? Lancet 344:7–8
Toda N (1983) Dopamine vasodilates human cerebral artery. Experientia 39: 1131–1132
Watson S, Girdlestone D. (1993) Receptor Nomenclature Supplement: Dopamine receptors. Trends Pharmacol Sci 14 (suppl): 13
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer-Verlag
About this chapter
Cite this chapter
Mühlbauer, B. (1996). Die therapeutische Wirksamkeit von Dopamin beim akuten Nierenversagen. In: Bardenheuer, H.J., Hilfiker, O., Larsen, R., Radke, J. (eds) Der Anaesthesist Weiterbildung für Anästhesisten 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60882-7_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-60882-7_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-63334-1
Online ISBN: 978-3-642-60882-7
eBook Packages: Springer Book Archive