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Die therapeutische Wirksamkeit von Dopamin beim akuten Nierenversagen

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Der Anaesthesist Weiterbildung für Anästhesisten 1997
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Zusammenfassung

Die therapeutische Wirksamkeit eines Arzneimittels gilt als erwiesen, wenn Scine erwünschten pharmakodynamischen Effekte in einem sinnvollen und kalkulierbaren Verhältnis zu den möglichen unerwünschten Wirkungen stehen. Erst der Nachweis einer günstigen Beeinflussung des Krankheitsverlaufes macht das Medikament zum Werkzeug einer rationalen Arzneimitteltherapie.

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Literatur

  1. Anderson RJ, Schlier RW (1988) Acute tubulär necrosis. In: (Hrsg) Schrier RW, Gottschalk CW. Diseases of the kidney. Little, Brown, Boston, S 1413–1446

    Google Scholar 

  2. Aperia A, Bertorello A, Seri I (1987) Dopamine causes Inhibition of Na, IC-ATPase activity in rat proximal convoluted tubule segments. Am J Physiol 252:F39–F45

    PubMed  CAS  Google Scholar 

  3. Baines AD, Drangova R (1984) Dopamine production by the isolated perfused rat kidney. Can J Physiol Pharmacol 62:272–276

    Article  PubMed  CAS  Google Scholar 

  4. Baldwin L, Henderson A, Hickman P (1994) Effect of postoperative lowdose dopamine on renal function after elective major vascular surgery. Ann Intern Med 120:744–747

    PubMed  CAS  Google Scholar 

  5. Ball SG, Gunn IG, Douglas IH (1982) Renal handling of dopa, dopamine, norepinephrine, and epinephrine in the dog. Am J Physiol 242:F56-F62

    PubMed  CAS  Google Scholar 

  6. Barger G, Ewins AJ (1910) Some phenolic derivatives of Phenylalanine. J Chem Soc 97:2263–2261

    Google Scholar 

  7. Bartholini G, Zivkovic B, Scatton B (1989) Dopaminergic neurons: basic aspects. In: Trendelenburg U, Weiner N (Hrsg) Handbook of Experimental Pharmacology: Catecholamines II. Springer, Berlin Heidelberg New York, S 277–318

    Chapter  Google Scholar 

  8. Chertow GM, Lazarus JM, Sayegh MH, Allgren RL (1995) Is the administration of dopamine associated with adverse outcomes in severe renal failure? J Am Soc Nephrol 6:460 (Abstract)

    Google Scholar 

  9. Costa P, Ottino GM, Matani A, Pansini S, Canavese C, Passerini G, Grezzana G (1990) Low-dose dopamine during cardiopulmonary bypass in patients with renal dysfunction. J Cardiothor Anesth 4:469–473

    Article  CAS  Google Scholar 

  10. Dasta JF, Kirby MG (1986) Pharmacology and therapeutic use of low-dose dopamine. Pharmacotherapy 6:304–310

    PubMed  CAS  Google Scholar 

  11. Felder CC, Campbell T, Albrecht F, Jose PA (1990) Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by Stimulation of adenylate cyclase. Am J Physiol 259:F297-F303

    PubMed  CAS  Google Scholar 

  12. Flancbaum L, Choban PS, Dasta JF (1994) Quantitative effects of low-dose dopamine on urine Output in Oligurie surgical intensive care unit patients. Crit Care Med 22:61–68

    PubMed  CAS  Google Scholar 

  13. Giraud GD, Maannell KL (1984) Decreased nutrient blood flow during dopamine- and epinephrine-induced intestinal vasodilation. J Pharmacol Exp Ther 230:214–220

    PubMed  CAS  Google Scholar 

  14. Goldberg LI, Kohli JD (1983) Peripheral dopamine reeeptors: A Classification based on potency series and specific antagonism. Trends Pharmacol Sci 4 (2): 64–66

    Article  CAS  Google Scholar 

  15. Greene SI, Smith JW. (1976) Dopamine gangrene. N Engl J Med 294: 114

    Article  PubMed  CAS  Google Scholar 

  16. Hayashi M, Yamaji Y, Kitajima W, Saruta T (1990) Aromatic L-amino acid decarboxylase activity along the rat nephron. Am J Physiol 258:F28-F33

    PubMed  CAS  Google Scholar 

  17. Hilberman M, Maseda J, Stinson EB, Derby GC, Spencer RJ, Miller DC, Oyer PE, Myers BD (1984) The diuretic properties of dopamine in patients after open-heart Operation. Anesthesiology 61: 489–494

    Article  PubMed  CAS  Google Scholar 

  18. Hoffman BB, Lefkowitz RJ (1990) Catecholamines and sympathomimetic drugs. In: Gilman AG, Rall TW, Nies AS, Taylor P (Hrsg) The pharmacological basis of therapeutics. Pergamon Press, New York, S 187–220

    Google Scholar 

  19. Holtz P, Credner K (1942) Die enzymatische Entstehung von Oxytyramin im Organismus und die physiologische Bedeutung der Dopadecarboxylase. Naunyn-Schmiedeberg’s Arch Pharmacol 200: 356–388

    Article  CAS  Google Scholar 

  20. Itskovitz HD, Chen YH, Stier CTJ (1988) Reciprocal renal effects of dopamine and 5-hydroxytryptamine formed within the rat kidney. Clin Sci 75: 503–507

    PubMed  CAS  Google Scholar 

  21. Kebabian JW, Calne DB (1979) Multiple reeeptors for dopamine. Nature 277:93–96

    Article  PubMed  CAS  Google Scholar 

  22. Kleinknecht D (1992) Management of acute renal failure. In: Cameron S, Davison AM, Grünfeld JP, Kerr D, Ritz E (Hrsg) Oxford Textbook of Clinical Nephrology. Oxford Medical Publications, Oxford, S 1015–1026

    Google Scholar 

  23. Le Corre P, Malledant Y, Tanguy M, Le Verge R (1993) Steady-state pharmacokinetics of dopamine in adult patients. Crit Care Med 21:1652–1657

    Article  Google Scholar 

  24. Lee MR. (1993) Dopamine and the kidney: 10 years on. Clin Sci 84:357–375

    PubMed  CAS  Google Scholar 

  25. Lokhandwala MF, Amenta F (1991) Anatomical distribution and function of dopamine reeeptors in the kidney. FASEB J 5:3023–3030

    PubMed  CAS  Google Scholar 

  26. Mannich C, Jacobsohn W (1910) Über Oxyphenylalkylamine und Diophenylalkylamine. Ber Dtsch Chem Ges 43:189–193

    Article  CAS  Google Scholar 

  27. Marik PE, Mohedin M (1994) The contrasting effects of dopamine and norepinephrine on systemic and splanchnic oxygen utilization in hyperdynamic sepsis. JAMA 272:1354–1357

    Article  PubMed  CAS  Google Scholar 

  28. Memoli B, Libetta C, Conte G, Andreucci VE (1994) Loop diuretics and renal vasodilators in acute renal failure. Nephrol Dial Transplant 9 Suppl 4: 168–171

    Google Scholar 

  29. Meyer MB, May JL, Goldberg LI (1967) Effects of dopamine on renal function and hemodynamics in the dog. J Pharmacol Exp Ther 156: 186–192

    PubMed  CAS  Google Scholar 

  30. Mühlbauer B, Hartenburg E, Osswald H (1994) Renal response to amino acid infusion in rats: effect of dopamine receptor antagonists and benserazide. Naunyn-Schmiedeberg’s Arch Pharmacol 349: 244–249

    Article  Google Scholar 

  31. Mühlbauer B, Osswald H (1992) Feeding but not salt loading is the dominant factor Controlling urinary dopamine excretion in conscious rats. Naunyn-Schmiedeberg’s Arch Pharmacol 346:469–471

    Article  Google Scholar 

  32. Mühlbauer B, Osswald H (1994) Feeding-induced increase in urinary dopamine excretion is independent of renal innervation and sodium intake. Am J Physiol 266:F563-F567

    PubMed  Google Scholar 

  33. Myles PS, Buckland MR, Schenk NJ, Cannon GB, Langley M, Davis BB, Weeks AM (1993) Effect of „renal-dose“ dopamine on renal function following cardiac surgery. Anaesth Intensive Care 21: 56–61

    PubMed  CAS  Google Scholar 

  34. Orme ML, Breckenridge A, Dollery CT (1973) The effects of long term administration of dopamine on renal function in hypertensive patients. Eur J Clin Pharmacol 6:150–155

    Article  PubMed  CAS  Google Scholar 

  35. Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Goldblatt E, Pescetti J (1987) Dopamine pharmacokinetics in critically ill newborn infants. J Pediatr 110:293–298

    Article  PubMed  CAS  Google Scholar 

  36. Parks RW, Diamond T, Mrory DC, Johnston GW, Rowlands BJ (1994) Prospective study of postoperative renal function in obstructive jaundice and the effect of perioperative dopamine. Br J Surg 81:437–439

    Article  PubMed  CAS  Google Scholar 

  37. Petrides PE (1990) Nervengewebe. In: Löffier G, Petrides P (Hrsg) Physiologische Chemie. Springer, Berlin Heidelberg New York, S 909–926

    Google Scholar 

  38. Polson RJ, Park GR, Lindop MJ, Farman JV, Calne RY, Williams R (1987) The prevention of renal impairment in patients undergoing orthotopic liver grafting by infusion of low dose dopamine. Anaesthesia 42:15–19

    Article  PubMed  CAS  Google Scholar 

  39. Puschett JB, Winaver J (1992) Effects of diuretics on renal function. In: Windhager EE (Hrsg) Handbook of Physiology (8): Renal Physiology. Oxford University Press, New York, S 2335–2406

    Google Scholar 

  40. Ratcliffe PJ (1992) Pathophysiology of acute renal failure. In: Cameron S, Davison AM, Grünfeld JP, Kerr D, Ritz E (Hrsg) Oxford Textbook of Clinical Nephrology. Oxford University Press, Oxford, S 982–1005

    Google Scholar 

  41. Reinsberg J, Kulimann R (1986) Characterization of vascular dopamine receptors in the gastric circulation of the rabbit. J Cardiovasc Pharmacol 8: 1067–1073

    Article  PubMed  CAS  Google Scholar 

  42. Rump LC, Schwertfeger E, Schuster MJ, Schaible U, Frankenschmidt A, Schollmeyer PJ (1993) Dopamine DA2-receptor activation inhibits noradrenaline release in human kidney slices. Kidney Int 43:197–204

    Article  PubMed  CAS  Google Scholar 

  43. Schwartz LB, Gewertz BL. (1988) The renal response to low dose dopamine. J Surg Res 45: 574–588

    Article  PubMed  CAS  Google Scholar 

  44. Seeman P (1980) Brain dopamine receptors. Pharmacol Rev 32: 229–313

    PubMed  CAS  Google Scholar 

  45. Seeman P, Van Toi HH (1994) Dopamine receptor pharmacology. Trends Pharmacol Sci 15:264–270

    Article  PubMed  CAS  Google Scholar 

  46. Sumikawa K, Hayashi Y, Yamatodani A, Yoshiya I. (1991) Contribution of the lungs to the clearance of exogenous dopamine in humans. Anesth Anaig 72:622–626

    CAS  Google Scholar 

  47. Swygert TH, Roberts LC, Valek TR, Brajtbord D, Brown MR, Gunning TC, Paulsen AW, Ramsay MA (1991) Effect of intraoperative low-dose dopamine on renal function in liver transplant reeipients. Anesthesiology 75:571–576

    Article  PubMed  CAS  Google Scholar 

  48. Thompson BT, Cockrill BA. (1994) Renal-dose dopamine: a siren song? Lancet 344:7–8

    Article  PubMed  CAS  Google Scholar 

  49. Toda N (1983) Dopamine vasodilates human cerebral artery. Experientia 39: 1131–1132

    Article  PubMed  CAS  Google Scholar 

  50. Watson S, Girdlestone D. (1993) Receptor Nomenclature Supplement: Dopamine receptors. Trends Pharmacol Sci 14 (suppl): 13

    Google Scholar 

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Mühlbauer, B. (1996). Die therapeutische Wirksamkeit von Dopamin beim akuten Nierenversagen. In: Bardenheuer, H.J., Hilfiker, O., Larsen, R., Radke, J. (eds) Der Anaesthesist Weiterbildung für Anästhesisten 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60882-7_1

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  • DOI: https://doi.org/10.1007/978-3-642-60882-7_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-63334-1

  • Online ISBN: 978-3-642-60882-7

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