Abstract
Atrial fibrillation (AF) is a common arrhythmia with significant clinical impact. Despite newer advances in arrhythmia treatment such as catheter ablation and implantable defibrillators, AF remains a domain for pharmacologic therapy. Although many clinical variables predisposing to AF have been determined (e.g., enlarged atrial size, valvular heart disease, hyperthyroidism), the electrophysiologic mechanisms leading to AF, its termination and its recurrence, are still insufficiently understood. This has made it difficult to apply pharmacologic therapy in a scientifically founded fashion.
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Franz, M.R. (1997). Excitable Gap, Antiarrhythmic Actions, Electrical Remodeling: The Role Of MAP Recording in Atrial Fibrillation And Other Atrial Tachyarrhythmias. In: Franz, M.R., Schmitt, C., Zrenner, B. (eds) Monophasic Action Potentials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60851-3_9
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DOI: https://doi.org/10.1007/978-3-642-60851-3_9
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