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Impact of Molecular Biology and New Technical Developments in Diagnostic Imaging pp 201–264Cite as

Intra- and intercellular Recognition of Cell Signaling Using Oligonucleotides

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Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 22))

Abstract

Cell growth, normal development, and diseases depend on interactions among groups of small molecules and macromolecules of structural and functional proteins and nucleic acids. Bucket brigades of several essential groups of signaling proteins carry messages from outside the cell membrane to the nucleus in order to make new mRNAs and proteins, new DNA, or new cells, to repair DNA, or to die by falling apart (apoptosis). This controlled process of cell growth and development is circumvented by several gene mutations in cancer cells. Mutated genes generate critical signaling proteins and make cancer cells independent of other cells and other normal proteins for rapid growth in benign or malignant tumors.

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Authors
  1. M. K. Dewanjee
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Editors and Affiliations

  1. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin, Spandauer Damm 130, 14050, Berlin-Charlottenburg, Germany

    W. Semmler

  2. Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Germany

    M. Schwaiger

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© 1997 Springer-Verlag Berlin Heidelberg

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Dewanjee, M.K. (1997). Intra- and intercellular Recognition of Cell Signaling Using Oligonucleotides. In: Semmler, W., Schwaiger, M. (eds) Impact of Molecular Biology and New Technical Developments in Diagnostic Imaging. Ernst Schering Research Foundation Workshop, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60844-5_12

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  • DOI: https://doi.org/10.1007/978-3-642-60844-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64581-5

  • Online ISBN: 978-3-642-60844-5

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