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Strategies for Immunointerventions in Dermatology pp 195–206Cite as

Development of a DNA Vaccine Againts Malignant Melanoma

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Abstract

Within the last 3 years, DNA vaccines have entered the scene as a radically new approach to prophylaxis of infectious disease. Surprisingly, if injected intramuscularly, the DNA is expressed in vivo much more efficiently than would have been predicted from tissue culture DNA transfections. Antibody responses and major histocompatibility complex (MHC) class I-restricted cytotoxic T cell responses (CTL) have been observed.

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Authors
  1. K. Moelling
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  2. B. Strack
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  3. M. Nawrath
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  4. J. Heinrich
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  5. C. Döhring
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  6. S. N. Wagner
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  7. J. Pavlovic
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Editor information

Editors and Affiliations

  1. Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH-8091, Zurich, Switzerland

    Günter Burg M.D. (Chairman) (Chairman)

  2. Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH-8091, Zurich, Switzerland

    Reinhard G. Dummer M.D.

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© 1997 Springer-Verlag Berlin Heidelberg

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Cite this chapter

Moelling, K. et al. (1997). Development of a DNA Vaccine Againts Malignant Melanoma. In: Burg, G., Dummer, R.G. (eds) Strategies for Immunointerventions in Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60752-3_17

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  • DOI: https://doi.org/10.1007/978-3-642-60752-3_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64539-6

  • Online ISBN: 978-3-642-60752-3

  • eBook Packages: Springer Book Archive

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