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Acute Lung Injury pp 258–275Cite as

Permissive Hypercapnia

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Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 30))

Abstract

Permissive hypercapnia (PH) is becoming a widely accepted strategy for decreasing ventilator-induced lung injury [1–13]. It is not a therapeutic endpoint, but rather the penalty we have to pay for decreasing alveolar ventilation when we give priority to the limitation of lung overdistension. Its rationale is the assumption that transitory effects of hypercapnia are less deleterious than the lung damage produced by conventional attempts to keep a target PaCO2 around 40 mmHg [13–15].

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Authors
  1. M. B. Amato
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Editor information

Editors and Affiliations

  1. Pulmonary and Critical Care, St. Paul Ramsey Medical Center, 640 Jackson Street, St. Paul, 55101, MN, USA

    John J. Marini

  2. Anaesthesia and Critical Care, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK

    Timothy W. Evans

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© 1998 Springer-Verlag Berlin Heidelberg

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Amato, M.B. (1998). Permissive Hypercapnia. In: Marini, J.J., Evans, T.W. (eds) Acute Lung Injury. Update in Intensive Care and Emergency Medicine, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60733-2_16

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  • DOI: https://doi.org/10.1007/978-3-642-60733-2_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64532-7

  • Online ISBN: 978-3-642-60733-2

  • eBook Packages: Springer Book Archive

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