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Non-Invasive Estimation of the Effective Pulmonary Blood Flow and Gas Exchange from Respiratory Analysis

  • P. Christensen
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 28)

Abstract

Monitoring of the effective pulmonary blood flow is important in the control of many intensive care therapies such as effect of drugs, optimization of PEEP level and ventilatory settings. A large number of methods have been developed for estimation of the effective pulmonary blood flow. However, only the indicator dilution combined with estimation of the pulmonary shunt have gained widespread use for clinical purposes. The drawback of the indicator dilution method is that it is an invasive method which require access to the pulmonary artery as well as a systemic artery. The increasing demands for noninvasive methods have led to the development of a number indirect methods of which the inert gas rebreathing method have gained most acceptance.

Keywords

Pulmonary Blood Flow Mixed Venous Blood Rebreathing Method Intensive Care Therapy Rebreathing Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Farhi LE, Haab P (1967) Mixed venous blood gas tensions and cardiac output by “bloodless” methods; recent developments and appraisal. Respir Physiol 2:225–233.CrossRefGoogle Scholar
  2. Butler J (1965) Measurement of cardiac output using soluble gases. In: Fenn WO, Rahn H (eds) Handbook of Physiology. Respiration. Am Physiol Soc, sect 3, vol II, chapt 62: 1489–1503Google Scholar
  3. Farhi LE, Nesarajah MS, Olszowka AJ, Metildi LA, Ellis AK (1976) Cardiac output determination by simple one-step rebreathing technique. Respir Physiol 28:141-159PubMedCrossRefGoogle Scholar
  4. Olhsson J, Wranne B (1986) Non-invasive assesment of cardiac output and stroke volume in patients during exercise: Evaluation of a CO2-rebreathing method. Eur J Appl Physiol 55:538–544.CrossRefGoogle Scholar
  5. Capek JM, Roy RJ (1988) Noninvasive Measurement of Cardiac Output Using Partial CO2 Re-breathing. IEEE Trans Biomed Eng 35:653–661.PubMedCrossRefGoogle Scholar
  6. Gama de Abreu M, Ragaller M, Quintel M, Albrecht DM (1996) Non-invasive, Semi-Continuous Pulmonary Capillary Blood Flow Measurement by a Partial CO2 Rebreathing Technique. Intensive Care Med 22 (Suppl 3) S 362.Google Scholar
  7. Kim TS, Rahn H, Farhi LE (1966) Estimation of true venous and arterial PCO2 by gas analysis of a single breath. J Appi Physiol 21:1338–1344.Google Scholar
  8. Srinivasan R (1986) An analysis of estimation of pulmonary blood flow by the single-breath method. J Appi Physiol 61:198–209.Google Scholar
  9. Grønlund J, Christensen P, Hansen LG (1987) Single-breath method for estimating pulmonary blood flow: Data reduction based on nonlinear curve fitting. Aviat Space Environ Med 58:1097–1102.PubMedGoogle Scholar
  10. Sackner MA, Greeneltch D, Heiman MS, Epstein S, Atkins N (1975) Diffusing Capacity, Membrane Diffusing Capacity, Blood Volume, Pulmonary Tissue Volume, and Cardiac Output Measured by a Rebreathing Technique. Am Rev Respir Dis 111:157–164.PubMedGoogle Scholar
  11. Bose CL, Lawson EE, Greene A, Mentz W, Friedman M (1986) Measurement of Cardiopulmonary Function in Ventilated Neonates with Respiratory Distress Syndrom Using Rebreathing Methodology. Pediatr Res 20:316–320.PubMedCrossRefGoogle Scholar
  12. Steinhart CM, Burch KD, Brudno S, Parker DH (1989) Noninvasive determination of effective (nonshunted) pulmonary blood flow in normal and injured lungs. Crit Care Med 17:349–353.PubMedCrossRefGoogle Scholar
  13. Christensen P, Andersen PK (1996) Clinical applicability of a rebreathing method for noninvasive estimation of effective pulmonary blood flow. Intensive Care Med 22 (Suppl 3) S 365.Google Scholar
  14. Clemensen P, Christensen P, Norsk P, Grønlund J (1994) A modified photo- and magneto-acoustic multigas analyzer applied in gas exchange measurements. J Appi Physiol 76: 2832–2839.Google Scholar
  15. Stout RL, Wessel HU, Paul MH (1975) Pulmonary blood flow determined by continuous analysis of pulmonary gas exchange. J Appi Physiol 38:913–918.Google Scholar
  16. Wendelboe Nielsen O, Hansen S, Grønlund J (1994) Precision and accuracy of a noninvasive inert gas washin method for determination of cardiac output in men. J Appi Physiol 76 (4): 1560–1565.Google Scholar
  17. Cander L, Forster RE (1959) Determination of pulmonary parenchymal volume and pulmonary capillary blood flow in man. J Appi Physiol 14:541–555.Google Scholar
  18. Kendrick AH, Rozkovec A, Papouchado M, West J, Laszlo G (1989) Single-breath breath-holding estimate of pulmonary blood flow in man: Comparison with direct Fick cardiac output. Clin Science 76:673–676.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • P. Christensen

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