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Traffic of Leukocytes Through the Maternofetal Placental Interface and Its Possible Consequences

  • Chapter
Reproductive Immunology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 222))

Abstract

If, as is often the case, pregnancy and the survival/acceptance of the semiallogeneic embryo can be referred to as a paradox, we can surely regard the existence of circulating immune cells on the “wrong” side of the fetoplacental barrier, as nothing less than a self-contradiction. The presence and possible functional consequences of fetal cells such as lymphocytes in maternal blood and vice versa is fascinating, provocative, and challenging from a number of biological, ethical, and philosophical aspects. This review summarizes the evidence that such a curious cell traffic does in fact take place in human pregnancy.

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  1. Department of Immunology, Microbiology, Pathology and Infectious Diseases Karolinska Institute Division of Pathology, F42 Huddinge University Hospital, Huddinge, S-141 86, Sweden

    Lars B. Olding M.D., Ph.D.

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© 1997 Springer-Verlag Berlin Heidelberg

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Papadogiannakis, N. (1997). Traffic of Leukocytes Through the Maternofetal Placental Interface and Its Possible Consequences. In: Olding, L.B. (eds) Reproductive Immunology. Current Topics in Microbiology and Immunology, vol 222. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60614-4_7

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  • DOI: https://doi.org/10.1007/978-3-642-60614-4_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64475-7

  • Online ISBN: 978-3-642-60614-4

  • eBook Packages: Springer Book Archive

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