Zusammenfassung
Nahrungsmittel können eine Vielzahl von Unverträglichkeitsreaktionen an Haut oder Schleimhäuten auslösen. Häufige Krankheitsbilder sind Kontakturtikaria, Quincke-Ödem, Stomatitis, Glossitis, Rhinitis, Bronchitis, Asthma bronchiale sowie gastrointestinale Symptome wie Diarrhö, Malabsorption und Pruritus ani. Zu den systemischen Reaktionen zählen Hautreaktionen wie Flush, Pruritus, Urtikaria, anaphylaktoide und anaphylaktische Reaktionen und die Provokation einer atopischen Dermatitis. Zu den Nahrungsmittelunverträglichkeiten kann man möglicherweise auch Immunkomplexerkrankungen, Entzündungen des Fettgewebes, allergische Kontaktdermatitiden, Arthralgien, Migräne und Morbus Crohn rechnen [39]. Über 45% der allergischen Reaktionen auf Nahrungsmittel äußern sich an der Haut. Der Rest betrifft vor allem den Respirationstrakt (20%), den Gastrointestinaltrakt (20%) oder das kardiovaskuläre System (15%) [57].
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Literatur
Abernathy-Carver KJ, Sampson HA, Picker LJ, Leung DYM (1995) Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 95: 913–918
Albani S, Avanzini MA, Plebani A, Scotta MS, Perversi S, Licardi G, Ugazio AG, Burgio GR (1989) Diagnostic value of a lymphocyte stimulation test in cow milk protein intolerance. Ann Allergy 63: 489–492
Arshad SH, Matthews S, Gant C, Hide DW (1992) Effect of allergen avoidance on development of allergic disorders in infancy. Lancet 339: 1493–1497
Atherton DJ, Sewell M, Soothill JF, Wells RS, Chilvers CE (1978) A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema. Lancet 1: 401–403
Beyer K, Niggemann B, Schulze S, Wahn U (1994) Serum tryptase and urinary 1 methylhistamine as parameters for monitoring oral food challenges in children. Int Arch Allergy Immunol 104: 348–351
Bischoff SC, Meyer J, Hermann A, Meyer PN, Zeck-Kapp G, Manns P (1995) Intestinal allergy provocation test by endoscopy: New diagnostic tool for food allergy? Gastroenterol 108: A784
Bishop JM, Hill DJ, Hosking CS (1990) Natural history of cow milk allergy: clinical outcome. J Pediatr 116: 862–867
Bock SA (1982) The natural history of food sensitivity. J Allergy Clin Immunol 69: 173–177
Bock SA, Atkins FM (1990) Patterns of food hypersensitivity during sixteen years of double-blind, placebocontrolled food challenges. J Pedriatr 117: 561–567
Bock SA, Sampson HA, Atkins FM, Zeiger RS, Lehrer S, Sachs M, Bush RK, Metcalfe DD (1988) Doubleblind, placebo-controlled food challenge (DBPCFC) as an official procedure: A manual. J Allergy Clin Immunol 82: 986–997
Boeker M, Werfel T (1995) Binding of antibodies of the activation antigens panel to mononuclear cells after antigen-specific stimulation in vitro. In: Schlossmann VSF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd RF (eds) Leukocyte Typing V. Oxford University Press, pp 1181–1182
Boeker M, Werfel T (1995) Binding of cytokine receptor panel mAb to mononuclear cells after antigen-specific stimulation in vitro. In: Schlossmann VSF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd RF (eds) Leukocyte Typing V. Oxford University Press, pp 1960–1961
Bosso JV, Simon RA (1991) Urticaria, angiooedema and anaphylaxis provoked by food additives. In: Metcalfe DD, Sampson HA, Simon RA (eds) Food allergy, adverse reactions to foods and food additives. Blackwell, Boston, 288–300
Bruijnzeel-Koomen C, Ortoloani C, Aas K, Bindslev-Jensen C, Björkstén B, Moneret-Vautrin D, Wüthrich B (1995) Adverse reactions to food. Allergy 50: 623–635
Burks AW, Mallory SB, Williams LW, Shirrell MA (1988) Atopic dermatitis: Clinical relevance of food hypersensitivity reactions. J Pediatr 113: 447–451
Czech W, Schopf E, Kapp A (1995) Release of sulfidoleukotrienes in vitro: Its relevance in the diagnosis of pseudoallergy to acetylsalicylic acid. Inflamm Res 44: 291–295
Ebner C, Hirschwehr R, Bauer L, Breiteneder H, Valenta R, Ebner H, Kraft D, Scheiner O (1995) Identification of allergens in fruits and vegetables: IgE cross reaction with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin). J Allergy Clin Immunol 95: 962–969
Engman WF, Weiss R, Engman MF (1936) Eczema and environment. Med Clin North Am 20: 651–663
Goldenhersh MA (1990) Atopic dermatitis and food hypersensitivity. New Engl J Med 322: 274
Gustafsson D, Lowhagen T, Andersson K (1992) Risk of developing atopic disease after early feeding with cows milk based formula. Arch Dis Child 67:1008–1010
Halken S, Host A, Hansen LG, Østerballe O (1992) Effect of an allergy prevention programme on the incidence of atopic symptoms in infancy: a prospective study of 159 „high risk“ infants. Allergy 47: 545–553
Hammar H (1977) Provocation with cows milk and cereals in atopic dermatitis. Acta Dermato Venereol (Stockh) 57: 159–163
Hänsch GM, Römer W, Voigtländer V, Rother U (1981) Effect of salicylates on the complement system: generation of mediators in vivo and in vitro. Clin Immunol Immunopathol 21: 228–236
Hide DW, Matthews S, Matthews L, Stevens M, Ridout S, Twiselton R, Gant C, Arshad SH 1994: Effect of allergen avoidance in infancy on allergic manifestations at age 2 years. J Allergy Clin Immunol 93: 842–846
Hill DJ, Duke AM, Hosking CS, Hidson IL (1988) Clinical manifestations of cows milk allergy in childhood. II: The diagnostic value of skin tests and RAST. Clin Allergy 18: 481–490
Kajosaari M, Saarinen UM (1983) Prophylaxis of atopic disease by six month total solid food elimination: evaluation of 135 exclusively breastfed infants in atopic families. Acta Paediatr Scand 72: 411–414
Kondo N, Agata H, Fukutomi O, Motoyoshi F, Orii T (1990) Lymphocyte response to food antigens in patients with atopic dermatitis who are sensitive to foods. J Allergy Clin Immunol 86: 253–260
Lenz P, Czech W, Schöpf E, Kapp A (1994) Eosinophils — Crucial target cells in pseudo-allergic reactions to acetylsalicylic acid? Arch Dermatol Res 286: 223
Lessof MH (1996) Diagnose und Therapie allergischer Erkrankungen des Gastrointestinaltraktes. In: Holgate ST, Church MK, Kapp A (Hrsg) Allergologie. Ullstein Mosby, Wiesbaden, S 273–280
Mattes RD (1991) Learned food aversions: A family study. Physiol Behav 50: 499–504
May CD, Alberto R (1972) In vitro responses of leukocytes to food proteins in allergic and normal children: Lymphocyte stimulation and histamine release. Clin Allergy 2: 335–344
Mayer J, Bischoff SC, Meyer PN, Wedemeyer J, Zeck-Kapp G, Manns MP (1996) Intestinale Allergenprovo-kation zur Diagnostik von Nahrungsmittelallergien. Allergologie 19: 150
Metcalfe DD, Sampson HA (1990) Workshop on experimental methology for clinical studies of adverse reactions to foods and food additives. J Allergy Clin Immunol 86: 421–442
Minor JD, Tolber SG, Frick OL (1980) Leukocyte inhibition factor in delayed onset food allergy. J Allergy Clin Immunol 66: 314–321
Niggemann B, Beyer K, Wahn U (1994) The role of eosinophils and their granule protein ECP in monitoring oral food challenge tests in children with food sensitive atopic dermatitis. J Allergy Clin Immunol 94:963–971
Niggemann B, Beyer K, Pohl C, Wahn U (1996) Diagnostisches Vorgehen beim Verdacht auf Nahrungsmittelallergie im Kindesalter. Monatsschr Kinderheilkd 144: 65–73
Ormerod AD (1996) Pathophysiologic der Urtikaria. In: Holgate ST, Church MK, Kapp A (eds) Allergologie. Ullstein Mosby, Wiesbaden, S 241–252
Reekers R, Beyer K, Niggemann N, Wahn U, Freihorst J, Kapp A, Werfel T (1996) The role of circulating food antigen specific lymphocytes in food allergic children with atopic dermatitis. Br J Dermatol 135: 935–941
Robertson DAF, Jones DB (1996) Pathophysiologic allergologischer Erkrankungen des Gastrointestinaltrakts. In: Holgate ST, Church MK, Kapp A (Hrsg) Allergologie. Ullstein Mosby, Wiesbaden, S 273–280
Rudski E, Czubalski K, Grzywa Z (1980) Detection of urticaria with food additives intolerance by means of diet. Dermatologica 161: 57–62
Saarinen UM, Kajosaari M, Backman A, Siimes MA (1979) Prolonged breast-feeding as prophylaxis for atopic disease. Lancet 2: 163–166
Sager N, Feldmann A, Schilling G, Kreitsch P, Neumann C (1992) House dust mite-specific T cells in the skin of subjects with atopic dermatitis: Frequency and lymphokine profile in the allergen patch test. J Allergy Clin Immunol 89: 801–810
Sampson HA (1992) The immunopathogenic role of food hypersensitivity in atopic dermatitis. Acta Dermatol Venereol (Stockh) 176: 34–37
Sampson HA, McCaskill CC (1985) Food hypersensitivity and atopic dermatitis: Evaluation of 113 patients. J Pediatr 107: 669–675
Sampson HA, Mendelson L, Rosen JP (1992) Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 327: 380–384
Sampson HA, Rowe J, Eigemann PA, Leung DYM, Huang SK (1996) Ovomucoid-specific CD8+ TH2-like cell lines in atopic dermatitis patients (AD) with egg allergy. J Allergy Clin Immunology 97: A423
Sloper KS, Wadsworth J, Brostoff J (1991) Children with atopic eczema. I: Clinical response to food elimination and subsequent double-blind food challenge. Quart J Med, New Series 80: 677–693
Suomalainen H, Soppi E, Isolauri E (1994) Evidence for eosinophil activation in cow’s milk allergy. Ped Allergy Immunol 5: 27–31
Voigtländer V, Hänsch GM, Rother U (1980) Effect of aspirin on complement in vivo. Int Arch Allergy Appl Immun 61: 145–149
Webber SA, Graham-Brown RA, Hutchinson PE, Burns DA (1989) Dietary manipulation in childhood atopic dermatitis. Br J Dermatol 121: 91–98
Werfel T, Ahlers G, Boeker M, Kapp A (1997) Characterization of specific T-cell responses to food antigens in atopic dermatitis (AD). In: Ring J, Vieluf D, Behrendt H (Hrsg) New trends in allergy IV. Springer-Verlag Berlin, S 233–236
Werfel T, Ahlers G, Reekers R, Boeker M, Kapp A (1996) Ekzemreaktionen auf Nahrungsmittelallergen bei atopischer Dermatitis: Klinische und immunologische Befunde. In: Wüthrich B (Hrsg) Nahrungsmittelallergien. Dustri Verlag, Deisenhofen, S 186–196
Werfel T, Ahlers G, Schmidt P, Boeker M, Kapp A, Neumann C (1997) Milk-responsive atopic dermatitis is associated with a casein-specific lymphocyte response in adolescent and adult patients. J Allergy Clin Immunol (im Druck)
Werfel T, Ahlers G, Schmidt P, Boeker M, Kapp A (1996) Detection of a K-casein specific lymphocyte response in milk-responsive atopic dermatitis. Clin Exp Allergy, 26: 1380–1386
Werfel T, Kapp A (1997) Ex-vivo-Untersuchungen bei allergologischen Erkrankungen. In: Pzybilla B, Bergmann KC, Ring J (Hrsg) Praktische allergologische Diagnostik. Chapman and Hall (im Druck)
Werfel T, Morita A, Grewe M, Renz H, Wahn U, Krutmann J, Kapp A (1996) Allergen-specificity of skin-in-filtrating T-cells is not restricted to a type 2 cytokine pattern in chronic skin lesions of atopic dermatitis. J Invest Dermatol 107: 871–876
Wüthrich B (1993) Zur Nahrungsmittelallergie. Allergologie 16: 280–287
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Kapp, A., Werfel, T. (1997). Nahrungsmittelallergie 1996. In: Plewig, G., Przybilla, B. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60534-5_32
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