Abstract
Twenty-four and 48 h after intraperitoneal injection of the rat with 20 mg 4-hydroxyamino-quinoline (4-HAQO)/kg body weight, the abdominal cavity contained a small amount of serosanguinous fluid. The pancreas was whitish and edematous and contained areas of fat necrosis and small hemorrhagic foci. Gross evidence of edema was apparent by 24 h after intravenous injection. Treatment with lower doses of 4-HAQO (7 mg/kg intraperitoneally or 10 mg/kg intravenously) did not change the normal appearance of the pancreas.
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Konishi, Y. (1997). Necrotizing Pancreatitis Induced by 4-Hydroxyaminoquinoline, Rat. In: Jones, T.C., Popp, J.A., Mohr, U. (eds) Digestive System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60473-7_44
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DOI: https://doi.org/10.1007/978-3-642-60473-7_44
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