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Corynebacterium kutscheri Infection, Liver, Mouse and Rat

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Digestive System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Infected animals often have no gross lesions, but clinically affected animals may be emaciated with starry coats, naso-ocular discharge, and dyspnea. Submandibular lymph nodes are enlarged. Lungs contain randomly distributed, single large to numerous miliary cream-colored foci surrounded by red zones. Single to several variably sized caseopurulent foci protrude from the hepatic capsule or lie deep within the parenchyma. Adhesions to pleura, pericardium, and peritoneum are frequent. Less frequently, similar foci can occur in kidney, heart, spleen, joints, skin, lymph nodes, prepucial glands, and middle ears. Lesions are often restricted to lung and liver in rats, but liver and kidney lesions predominate in mice (Brownstein et al. 1985; Fauve et al. 1964; Ford and Joiner 1968; Giddens et al. 1968; Kutscher 1894; Matheson et al. 1955; Nelson 1973; Tadokoro et al. 1961; Weisbroth 1979; Weisbroth and Scher 1968a).

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Authors
  1. Stephen W. Barthold
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Editors and Affiliations

  1. Harvard Medical School, ILSI Research Foundation, 1126 Sixteenth Street. N.W, 20036, Washington, DC, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) (Professor of Comparative Pathology, Emeritus)

  2. Toxicology U.S, Sanofi Winthrop, Nine Great Valley Parkway, 19355, Malvern, PA, USA

    James A. Popp D.V.M., Ph.D. (International Director of Toxicology, Vice President) (International Director of Toxicology, Vice President)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1997 Springer-Verlag Berlin Heidelberg

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Barthold, S.W. (1997). Corynebacterium kutscheri Infection, Liver, Mouse and Rat. In: Jones, T.C., Popp, J.A., Mohr, U. (eds) Digestive System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60473-7_30

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  • DOI: https://doi.org/10.1007/978-3-642-60473-7_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64421-4

  • Online ISBN: 978-3-642-60473-7

  • eBook Packages: Springer Book Archive

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