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Drug Toxicity in Embryonic Development II pp 161–190Cite as

Cardiovascular Active Drugs

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 124 / 2))

Abstract

There are many classes of therapeutic agents whose primary action is on the cardiovascular system. These include antihypertensive drugs (e.g., beta-blocking agents and calcium antagonists), antiarrhythmics (e.g., potassium channel inhibitors), and sympathomimetic drugs (e.g., epinephrine). Other substances, such as ergotamine and vasopressin, are vasoactive and are used for special indications. In addition, other drugs whose primary action is on other organ systems (mainly the central nervous system) such as phenytoin, caffeine, nicotine, and the narcotic drug cocaine also exert pharmacological action on the cardiovascular system as a side effect.

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Authors
  1. B. R. Danielsson
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  2. W. S. Webster
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Editors and Affiliations

  1. Reproductive Toxicology Division (MD-71) National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, 27711, NC, USA

    Robert J. Kavlock Ph.D. (Director) (Director)

  2. Miami Valley Laboratories, The Procter and Gamble Company, P.O. Box 538707, 53239, Cincinnati, OH, USA

    George P. Daston Ph.D.

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Danielsson, B.R., Webster, W.S. (1997). Cardiovascular Active Drugs. In: Kavlock, R.J., Daston, G.P. (eds) Drug Toxicity in Embryonic Development II. Handbook of Experimental Pharmacology, vol 124 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60447-8_4

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