Skip to main content

Gastroösophagealer Reflux im Kindesalter

  • Chapter
Gastrointestinale Funktionsstörungen
  • 55 Accesses

Zusammenfassung

Der gastroösophageale Reflux im Kindesalter ist kein einheitliches Krankheitsbild mit fest umrissenen diagnostischen und therapeutischen Prinzipien. Schon die Abgrenzung des physiologischen vom pathologischen Reflux bereitet Schwierigkeiten. Nach Menardi [59] liegt ein pathologischer Reflux vor, wenn er Symptome verursacht oder nach dem 6. Lebensmonat auftritt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Adzick NS, Fisher JH, Winter HS, Sandler RH, Hendren WH (1989) Esophageal adenocarcinoma 20 years after esophageal atresia repair. J Pediatr Surg 24: 741–744

    Article  PubMed  CAS  Google Scholar 

  2. Ahrens P, Heller K, Keul HG, Zielen S, Kitz R, Hofmann D (1993) Recurrent aspiration in children: The diagnostic value of bronchoalveolar lavage. Am Rev Resp Dis 147: 585

    Google Scholar 

  3. Alrabeeah A, Giacomantonio M, Gillis DA (1988) Paraesophageal hernia after Nissen fundoplication: A real complication in pediatric patients. J Pediatr Surg 23: 766–768

    Article  PubMed  CAS  Google Scholar 

  4. Ashcraft KW, Holder TM, Amoury RA, Sharp RJ, Murphy JP (1984) The Thal fundoplication für gastroesophageal reflux. J Pediatr Surg 19: 480–483

    Article  PubMed  CAS  Google Scholar 

  5. Behar J, Sheahan D (1975) Histologic abnormalities in reflux esophagitis. Arch Pathol 9: 387–391

    Google Scholar 

  6. Berquist WE, Rachelefsky GS, Kadden M, Siegel S (1981) Gastroesophageal reflux-associated recurrent pneumonia and chronic asthma in children. Pediatrics 68: 29–35

    PubMed  CAS  Google Scholar 

  7. Bettex M, Kuffer F (1969) Long-term results of fundoplication in hiatus hernia and cardioesophageal chalasia in infants and children. J Pediatr Surg 4: 526–530

    Article  PubMed  CAS  Google Scholar 

  8. Biller JA (1983) Are endoscopic changes predictive of histologic esophagitis in children. J Pediatr 103: 215–218

    Article  PubMed  CAS  Google Scholar 

  9. Black TL, Fernandes ET, Ellis DG, Hollabaugh RS, Hixson SD, Mann CM, Miller JP, Wrenn Jr. E (1991) The effect of tubegastrostomy on gastroesophageal reflux in patients with esophageal atresia. J Pediatr Surg 26: 168–170

    Article  PubMed  CAS  Google Scholar 

  10. Blake KD, Russell-Eggit IM, Morgan DW, Ratcliffe JM, Wyse RKH (1990) Who’s in CHARGE? Multidisziplinary management of patients with CHARGE association. Arch D is Childhood 65: 217–223

    Article  CAS  Google Scholar 

  11. Boerema I (1969) Hiatus hernia: repair by rightsided, subhepatic, anterior gastropexy. Surgery 65: 884–893

    PubMed  CAS  Google Scholar 

  12. Borgstein ES, Heij HA, Beugelaar JD, Ekkelkamp S, Vos A (1994) Risks and benefits of antireflux operations in Neurologically impaired children. Eur J Pediatr 153: 248–251

    Article  PubMed  CAS  Google Scholar 

  13. Bray PF, Herbst JJ, Johnson DG, Book LS, Ziter FA, Condon VR (1977) Childhood gastroesophageal reflux. neurologic and psychiatric syndromes mimicked. JAMA 237: 1342–1345

    Article  PubMed  CAS  Google Scholar 

  14. Buts JP, Barudi C, Moulin D, Claus D, Cornu G (1986) Prevalence and treatment of silent gastro-oesophageal reflux in children with recurrent respiratory disorders. Europ J Pediatr 145: 396–400

    Article  CAS  Google Scholar 

  15. Cahill JL, Aberdeen E, Waterston DJ (1969) Results of surgical treatment of esophageal hiatal hernia in infancy and childhood. Surgery 66: 597–602

    Google Scholar 

  16. Caniano DA, Ginn-Pease ME, King DR (1990) The failed antireflux procedure: Analysis of risk factors and morbidity. J Pediatr Surg 25: 1022–1026

    Article  PubMed  CAS  Google Scholar 

  17. Carre JJ (1959) The natural history of the partial thoracic stomach (hiatal hernia) in children. Arch Dis Child 34:344–348

    Article  PubMed  CAS  Google Scholar 

  18. Collins BJ, Elliott H, Sloan JM (1985) oesophageal histology in reflux oseophagitis. J Clin Pathol 38:1265–1272

    Article  PubMed  CAS  Google Scholar 

  19. Colombo J (1987) Lipid-laden alveolar macrophage quantitation. Ped Pulmol 3: 86–89

    Article  CAS  Google Scholar 

  20. Colombo JJ, Hallberg T, Sammut P (1992) Time course of lipid-laden pulmonary macrophages with acute and recurrent milk aspiration in rabbits. Ped Pulmo 112:95–98

    Article  Google Scholar 

  21. Cooper JE, Spitz L, Wilkins BM (1987) Barrett’s esophagus in children: A histologic and histochemical study of 11 cases. J Pediatr Surg 22: 191–196

    Article  PubMed  CAS  Google Scholar 

  22. Corbally MT, Muftah M, Guiney EJ (1992) Nissen fundoplication for gastro-esophageal reflux in repaired tracheo-esophageal fistula. Eur J Pediatr Surg 2: 332–335

    Article  PubMed  CAS  Google Scholar 

  23. Coran A (1990) Diskussion zu Caniano et al. [16]

    Google Scholar 

  24. DeMeester TR (1980) Technique, indications and clinical use of 24 hour esophageal pH monitoring. J Thorac Cardiovasc Surg 79: 656–670

    PubMed  CAS  Google Scholar 

  25. Donelly RJ, Berrisford RG, Jack C (1993) Simultaneous tracheal and esophageal pH monitoring: Investigating reflux-associated asthma. Ann Thorac Surg 56:1029–1034

    Article  Google Scholar 

  26. Drucker DEM, Michna BA, Krummel TM, Hunt PK, Hartenberg MA, Salzberg AM (1989) Transthoracic Nissen fundoplication for gastroesophageal reflux in patients with severe kypho-roto-scoliosis. J Pediatr Surg 24: 46–47

    Article  PubMed  CAS  Google Scholar 

  27. Ein S (1990) Diskussion zu Caniano et al. [16]

    Google Scholar 

  28. ESPGAN-Working Group of the European Society of Pediatric Gastroenterology and Nutrition (1990) A standardized protocol for the methodology of esophageal pH-Monitoring and interpretation of data for the diagnosis of gastroesophageal reflux. J Ped Gastroent Nutr 14: 467–471

    Google Scholar 

  29. Euler AR, Byrne WJ (1979) Recurrent pulmonary disease in children: A complication of gastroesophageal reflux. Pediatrics 63:47–51

    PubMed  CAS  Google Scholar 

  30. Fawcett HD, Hayden CK, Adams JC (1988) How useful is gastroesophageal reflux scintigraphy in suspected childhood aspiration. Pediatr Radio1 18: 311–313

    Article  CAS  Google Scholar 

  31. Fonkalsrud EW, Foglia RP, Ament ME, Berquist W, Vargas J (1989) Operative treatment for the gastroesophageal reflux syndrome in children. J Pediatr Surg 24: 525–529

    Article  PubMed  CAS  Google Scholar 

  32. Gdanietz K, Lempe M (1991) The transthoracic hiatoplasty for cases of non-operable gastroesophageal reflux. Eur J Pediatr Surg 1: 230–232

    Article  PubMed  CAS  Google Scholar 

  33. Hall BD (1979) Choanal atresia and associated multiple anomalies. J Pediatr 95: 395–398

    Article  PubMed  CAS  Google Scholar 

  34. Hanimann B, Sacher P, Stauffer UG (1993) Complications and long-term results of the Nissen fundoplication. Eur J Pediatr Surg 3:12–14

    Article  PubMed  CAS  Google Scholar 

  35. Harnsberger JK, Corey JJ, Johnson DG, Herbst JJ (1983) Long-term follow-up of surgery for gastroesophageal reflux in infants and children. Pediatrics 102: 505–508

    Article  CAS  Google Scholar 

  36. Harvey AS, Leaper PM, Bankie A (1991) CHARGE association: Clinical manifestations and developement outcome. Am J Med Genetics 39:48–55

    Article  CAS  Google Scholar 

  37. Heij HA, Ekkelkamp S, Vos A (1988) Long-term results of anterior gastropexy of gastroesophageal reflux in children. Pediatr Surg Int 4: 256–259

    Google Scholar 

  38. Herbst JJ (1981) Gastroesophageal reflux. J Pediatr 98: 859–870

    Article  PubMed  CAS  Google Scholar 

  39. Herbst JJ, Minton SD, Book LS (1979) Gastroesophageal reflux causing respiratory distress and apnoe in newborn infants. J Pediatr 95: 763–768

    Article  PubMed  CAS  Google Scholar 

  40. Herbst JJ, Minton SD, Book LS (1979) Gastroesophageal reflux causing respiratory distress and apnoe in newborn infants. J Pediatr 95: 763–768

    Article  PubMed  CAS  Google Scholar 

  41. Hillemeier AC, Lange R, McCallum R (1981) Delayed gastric emptying in infants with gastrooesophageal reflux. J Pediatr 98: 190–193

    Article  PubMed  CAS  Google Scholar 

  42. Hillemeier AC, Grill BB, McCallum R (1983) Esophageal and gastric motor abnormalities in gastroesophageal reflux during infancy. Gastroenterology 84: 741–745

    PubMed  CAS  Google Scholar 

  43. Hoeffel JC, Nihoul-Fékété C, Schmitt M (1989) Esophageal adenocarcinoma after gastroesophageal reflux in children. J Pediatrics 115: 259–261

    Article  CAS  Google Scholar 

  44. Höllwarth ME, Uray E, Deinsberger R (1991) Stellenwert und Behandlung des gastroösophagealen Reflux im Kindesalter. Chir Gastroenterol 1: 15–22

    Google Scholar 

  45. Johansson KE, Tibbling L (1985) Evaluation of the 24-hour pH-test at two different levels of the oesophagus. In: DeMeester TR, Sinner DB (eds) Esophageal disorders: Pathophysiology and therapy. Raven Press New York, 88:579–582

    Google Scholar 

  46. Jolley SG, Tunell WP, Hoelzer DJ et al. (1986) Lower esophageal pressure changes with tube gastrostomy: a causative factor of gastroesophageal reflux in children? J Pediatr Surg 21: 624–627

    Article  PubMed  CAS  Google Scholar 

  47. Kamei R (1991) Chronic cough in children. Pediatr Clin North Am 38: 741–745

    Google Scholar 

  48. Kiely E, Spitz L (1987) Is routine gastrostomy necessary in the management of esophageal atresia. Pediatr Surg Int 2: 6–9

    Google Scholar 

  49. Kinsburn M (1984) Hiatus hernis with contorsions of the neck. Lancet 1: 1058–1064

    Google Scholar 

  50. Koch A, Rohr S, Plaschkes J, Bettex M (1986) Incidence of gastroesophageal reflux following repair of esophageal atresia. Prog Pediatr Surg 19: 103–113

    PubMed  CAS  Google Scholar 

  51. Koot VCM, Bergmeijer HJ, Bos AP, Molenaar JC (1993) Incidence and management of gastroesophageal reflux after repair of congenital diaphragmatic hernia. J Pediatr Surg 28:48–52

    Article  PubMed  CAS  Google Scholar 

  52. Kuffer F, Bettex M (1984) Die Hiatushernie des Kleinkindes. Früh-und Spätkomplikationen nach Fundoplikatio. Z Kinderchir 14: 153–164

    Google Scholar 

  53. Lacey SR, Cooper C, Runyan DK, Azizkhan RG (1993) Munchausen syndrome by proxy: Patterns of presentation to pediatric surgeon. J Pediatr Surg 28: 827–832

    Google Scholar 

  54. Lancet (1982) Leading article. Gastro-oesophageal reflux in children. Lancet 1: 144–145

    Google Scholar 

  55. Leape IL, Ramenofsky ML (1980) Surgical treatment of gastroesophageal reflux in children. Am J Dis Child 134: 935–938

    PubMed  CAS  Google Scholar 

  56. Lindahl H, Rintala R, Sariola H (1993) Chronic esophagitis and gastric metaplasia are frequent late complications of esophageal atresia. J Pediatr Surg 28: 1176–1180

    Article  Google Scholar 

  57. Malfroot A, Vandenplas Y, Verlinden M, Piepsz A (1987) Gastroesophageal reflux and unexplained chronic respiratory disease in infants and children. Pediatr Pulmol 3: 208–213

    Article  CAS  Google Scholar 

  58. McCallum R, Berkowitz DM, Lerner E (1981) Gastric emptying in patients with gastroesophageal reflux. Gastroenterology 80: 285–291

    PubMed  CAS  Google Scholar 

  59. Menardi G: Der gastro-ösophageale Reflux (1983) Z Allg Med 59:1525–1528

    CAS  Google Scholar 

  60. Mendelson C (1946) The aspiration of stomach contents into the lungs during obstetric anesthesia. Am J Obstet Gynecol 52: 191–205

    PubMed  CAS  Google Scholar 

  61. Menon A, Schefft G, Thach B (1985) Apnoe associated with regurgitation in infants. J Pediatr 106: 625–629

    Article  PubMed  CAS  Google Scholar 

  62. Meyers WF (1985) Value of tests for evaluation of gastroesophageal reflux in children. J Pediatr Surg 20: 515–520

    Article  PubMed  CAS  Google Scholar 

  63. Mollitt DL, Golladay S, Seibert JJ (1985) Symptomatic gastroesophageal reflux in neurologically mpaired patients. Pediatrics 75: 1124–1128

    PubMed  CAS  Google Scholar 

  64. Montgomery M, Frenckner B (1993) Esophageal atresia: Mortality and complications related to gastroesophageal reflux. Eur J Pediatr Surg 3: 335–338

    Article  PubMed  CAS  Google Scholar 

  65. Müller-Lissner S, Starlinger M, Koelz HR (1989) Reflux-Fibel. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  66. Naik DR, Moore DJ (1984) Ultrasound diagnosis of gastroesophageal reflux. Arch Dis Childh 59: 366–379

    Article  PubMed  CAS  Google Scholar 

  67. Naik DR, Bolia A, Moore DJ (1985) Comparison of barium swallow and ultrasound in diagnosis of gastro-oesophageal reflux in children. Br Med J 29: 1943–1945

    Article  Google Scholar 

  68. Nussbaum E, Maggi C, Mathis R (1987) Association of lipid-laden alveolar macrophages and gastroesophageal reflux in children. J Pediatr 110: 190–194

    Article  PubMed  CAS  Google Scholar 

  69. Orenstein SR (1990) Prone positioning in infant gastroesophageal reflux: Is elevation of the head worth the trouble? J Pediatrics 117: 184–187

    Article  CAS  Google Scholar 

  70. Parker AF, Christie DL, Cahill (1979) Incidence and significance of gastroesophageal reflux following repair of esophageal atresia and tracheoesophageal fistula and the need for antireflux procedures. J Pediatr Surg 14: 5–8

    Article  PubMed  CAS  Google Scholar 

  71. Pearl RH, Robie DK, Ein SH et al. (1990) Complications of gastroesophageal antireflux surgery in neurologically impaired versus neurologically normal children. J Pediatr Surg 25: 1169–1173

    Article  PubMed  CAS  Google Scholar 

  72. Pieretti R, Shanding B, Stephens A (1974) Resistant esophageal stenosis associated with reflux after repair of esophageal atresia: A therapeutic approach. J Pediatr Surg 9: 355–357

    Article  PubMed  CAS  Google Scholar 

  73. Puntis JWL, Smith HL, Buick RG, Booth IW (1989) Effect of dystonic movements on oesophageal peristalsis in Sandifer’s syndrome. Arch Dis Childh 64: 1311–1313

    Article  PubMed  CAS  Google Scholar 

  74. Rakowsky T (1994) Ösophagus-pH-Metrie und simultane Magen-Ösophagus-pH-Metrie bei milchernährten Säuglingen. Monatsschr Kinderheilk 142:52–56

    Google Scholar 

  75. Reid N (1992) Complicating features of asthma. Pediatr Clin North Am 39: 1327–1342

    PubMed  CAS  Google Scholar 

  76. Riccabona M, Maurer U, Lackner H, Uray E (1992) The role of sonography in the evaluation of gastro-oesophageal reflux-correlation to pH-metry. Eur J Pediatr 151: 655–657

    Article  PubMed  CAS  Google Scholar 

  77. Rice H, Seashore JH,Touloukian RJ (1991) Evaluation of Nissen fundoplication in neurologically impaired children. J Pediatr Surg 26: 697–701

    Article  PubMed  CAS  Google Scholar 

  78. Rösch W, Armstrong D, Blum AL (1993) Volkskrankheit Sodbrennen: Vom „pathologischen Reflux“ zur Refluxösophagitis. Dtsch Ärztebl 90: 152–157

    Google Scholar 

  79. Rossetti M (1966) Traitement chirurgical des hernies hiatales. J Chir (Paris) 92: 88–93

    Google Scholar 

  80. Roviralta AE (1951) Las asociaciones etiologicas en los sindromes ementizantes del lactante. El sindrome freno-pilorico. Med Clin (Barcelona) 16: 408–416

    Google Scholar 

  81. Sacher M, Novak W (1987) Dystonie als Komplikation bei gastrooesophagealem Reflux: Sandifer Syndrom. Monatsschr Kinderheilk 135: 857–858

    CAS  Google Scholar 

  82. Savary M, Miller G (1977) Osophagus-Lehrbuch und Atlas. Gassmann, Solothurn

    Google Scholar 

  83. Schärli AF (1992) Esophageal reconstruction in very long atresias by elongation of the lesser curvature. Pediatr Surg Int 7: 101–105

    Article  Google Scholar 

  84. Shepherd RW, Wren J, Evans S, Lander M, Ong T (1987) Gastroesophageal reflux in children. Clin Pediatr 26: 55–60

    Article  CAS  Google Scholar 

  85. Shono T, Suita S, Arima T, Handa N, Ishii K, Hirose R, Sakaguchi T (1991) Motility function of the esophagus before primary anastomosis in esophageal atresia. J Pediatr Surg 28: 673–676

    Article  Google Scholar 

  86. Shub M, Ulshen M, Hargrove C (1984) Esophagitis: A frequent consequence of gastroesophageal reflux in infancy. J Pediatr 107: 881–884

    Google Scholar 

  87. Siewert J, Classen M (eds) (1993) Gastroenterologische Diagnostik. Schattauer, Stuttgart New York

    Google Scholar 

  88. Sladen GE, Riddell RH, Willoughby JM (1975) Oesophagoscopy, biopsy and acid perfusion test in diagnosia of „reflux oesophagitis“. Br Med J 1: 71–76

    Article  PubMed  CAS  Google Scholar 

  89. Sondheimer J (1988) Gastroesophageal reflux: Update on pathogenesis and diagnosia. Pediatr Clin North Am 35: 103–116

    PubMed  CAS  Google Scholar 

  90. Sonnenberg A, Lepsien G, Müller-Lissner S (1982) When is esophagitis healed? Dig Dis Sci 27: 297–302

    Article  PubMed  CAS  Google Scholar 

  91. Spitz L (1984) Gastric transposition via the mediastinal route for infants with long-gap esophageal atresia. J Pediatr Surg 19: 149–154

    Article  PubMed  CAS  Google Scholar 

  92. Steinschneider A, Weinstein S, Diamond E (1982) The Sudden Infant Death Syndrome and apnoe/obstruction during neonatal sleep and feeding. Pediatrics 7o: 858–863

    Google Scholar 

  93. Takano K, Iwafuchi M, Uchiyama M, Yagi M, Ueno A, Iwasaki M (1988) Evaluation of lower esophageal sphincter function in infants and children following esophageal surgery. J Pediatr Surg 23: 410–414

    Article  PubMed  CAS  Google Scholar 

  94. Thal AP, Hatafuku T, Kurtzman R (1965) New operation for distal esophageal stricture. Arch Surg 90: 464–472

    PubMed  CAS  Google Scholar 

  95. Tovar JA, Gorostiaga L, Echeverry J, Torrado J, Eizaguirre I, Garay I (1993) Barretts’s oesophagus in children and adolescents. Pediatr Surg Int 8:389–394

    Article  Google Scholar 

  96. Tuggle DW, Tunell WP, Hoelzer DJ, Smith EI (1988) The efficacy of Thal fundoplication in the treatment of gastroesophageal reflux: The influence of central nervous system impairment. J Pediatr Surg 23: 638–640

    Article  PubMed  CAS  Google Scholar 

  97. Turnage RH, Oldham KT, Coran AG, Blane CE (1989) Late results of fundoplication for gastro esophageal reflux in infants and children. Surgery 457–463

    Google Scholar 

  98. Vandenplas Y (1992) Oesophageal pH monitoring for gastro-oesophageal reflux in infants and children. Wiley, Chichester New York Brisbane Toronto Singapore

    Google Scholar 

  99. Yandenplas Y, Sacre L, Loeb H (1989) pH-Monitoring in children. Neth J Med 34: 62–73

    Google Scholar 

  100. Waag KL, Heller K, Brand M (1990) Gastric transposition for primary anastomosis in long-gap esophageal atresia. In: Willital GH, Nihoul-Fékété C, Myers N (eds) Management of esophageal atresia. Urban & Schwarzenberg, München Wien Baltomore, pp 61–65

    Google Scholar 

  101. Willigens P, Ahrens P, Kitz R, Zielen S, Hofmann D (1994) Diagnostik der gastroösophagealen Refluxkrankheit. Normwerte für die 2-Punkt-pH-Metrie. Monatsschr Kinderheilk (Suppl) 143: 315

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Heller, K., Ahrens, P. (1997). Gastroösophagealer Reflux im Kindesalter. In: Fuchs, KH., Stein, H.J., Thiede, A. (eds) Gastrointestinale Funktionsstörungen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60372-3_45

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-60372-3_45

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64375-0

  • Online ISBN: 978-3-642-60372-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics