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Zingiber Officinale

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Adverse Effects of Herbal Drugs

Part of the book series: Adverse Effects of Herbal Drugs ((HERBAL DRUGS,volume 3))

Abstract

Zingiber officinale Roscoe, usually known as ginger, belongs to the family Zingiberaceae. The genus zingiber comprises some 80–90 species which are perennial aromatic herbs with fleshy rhizomes and tuberous roots. The chief commercial varieties of ginger are Chinese, Nigerian, Cochin and Jamaican, reflecting the fact that the plant is grown in areas as diverse as China, India [Cochin], Nigeria, Sierra Leone, Sri Lanka, Vietnam, Australia and Jamaica. Fresh ginger is sun-dried in the country of origin. It may or may not be peeled [‘scraped’] to remove cork [1]. The official British Pharmacopoeia grade is defined as„the rhizome of Zingiber officinale Roscoe scraped or unscraped. It is known in commerce as unbleached ginger” [2].

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References

  1. Govindarajan VS (1982) Ginger-chemistry, technology and quality evaluation: part 1. CRC Crit Rev Food Sci Nutr 17: 1–96 and 189–258

    Article  CAS  Google Scholar 

  2. Anonymous (1993) British Pharmacopoeia. London HMSO Volume 1: 305

    Google Scholar 

  3. Connell DW (1970) The chemistry of the essential oil and oleoresin of ginger (Zingiber officinale Roscoe). Flavour Industry 1: 677–693

    Google Scholar 

  4. Lawrence BM (1984) Major tropical spices-ginger (Zingiber officinale Rose.). Perfumer Flavorist 9: 1–40

    CAS  Google Scholar 

  5. MacLeod AJ, Pieris NM (1984) Volatile aroma constituents of Sri Lankan ginger. Phytochemistry 23: 353–359

    Article  CAS  Google Scholar 

  6. Van Beek TA, Posthumus MA, Lelyveld GP, Phiet HV and Yen BT (1987) Investigation of the essential oil of Vietnamese ginger. Phytochemistry 26: 3005–3010

    Article  Google Scholar 

  7. Anonymous (1949) The British Pharmaceutical Codex. The Pharmaceutical Press London, p. 1239

    Google Scholar 

  8. Steinegger E, Stucki K (1982) Trennung und quantitative Bestimmung der Hauptscharfstoffe von Zingiberis Rhizoma mittels kombinierter DC/HPLC. Pharm Acta Helv 57: 66–71

    CAS  Google Scholar 

  9. Connell DW, Sutherland MD (1969) A re-examination of gingerol, shogaol and zingerenone, the pungent principles of Ginger (Zingiber officinale Roscoe). Aust J Chem 22: 1033–1043

    Article  CAS  Google Scholar 

  10. Hikino H (1985) Recent research on oriental medicinal plants In: Wagner H, Hikino H, Farnsworth NR (red) Economic and Medicinal Plant Research: Vol 1. London Academic Press pp. 61–85

    Google Scholar 

  11. Connell DW, McLachlan R (1972) Natural pungent Compounds. Examination of the gingerols, shogaols, paradols and related compounds by Thin-layer and Gas Chromatography. J Chromatogr 67: 29–35

    Article  CAS  Google Scholar 

  12. Endo K, Kanno E and Oshima Y (1990) Structures of antifungal diarylheptenones, gingerenones ABC and isogingerenone B, isolated from the rhizomes of Zingiber officinale. Phytochemistry 29: 797–799

    Article  CAS  Google Scholar 

  13. Huang Q, Iwamoto M, Aoki et al. (1992) Anti-5-hydroxytryptamine3 effect of galanolactone, diterpenoid isolated from Ginger. Chem Pharm Bull 39: 397–399

    Google Scholar 

  14. Yoshikawa M, Hatakeyama S, Taniguchi K, Matuda H, Yamahara J (1992) 6-Gingesulfonic acid, a new anti-ulcer principle, and gingerglycolipids A, B and C. Three new monoacyldigalactosylglycerols, from Zingiberis Rhizoma originating in Taiwan. Chem Pharm Bull. 40: 2239–2241

    PubMed  CAS  Google Scholar 

  15. Yoshikawa M, Hatakeyama S, Chatani M, Nishino Y, Yamahara J (1993) Qualitative and quantitative analysis of bioactive principles in Zingeribis Rhizoma by means of high Performance liquid chromatography and gas liquid chromatography. On the evaluation of Zingeribis Rhizoma and chemical change of constituents during Zingeribis Rhizoma processing. Yakugaku Zasshi 113: 307–315

    PubMed  CAS  Google Scholar 

  16. Tanabe M, Chen Y-D, Saito K-I, Kono Y (1993) Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe. Chem Pharm Bull 41: 710–713

    PubMed  CAS  Google Scholar 

  17. Leung AY (1980) Encyclopedia of common natural ingredients used in food, drugs and cosmetics. New York: Wiley-Interscience pp. 184–186

    Google Scholar 

  18. Pancho LR, Kimura I, Unno R, Kurino M and Kimura M (1989) Reversed effects between crude and processed ginger extracts on PGF2α-induced contraction in mouse mesenteric veins. Jap J Pharmacol 50: 243–246

    Article  PubMed  CAS  Google Scholar 

  19. Mascolo N, Jain R, Jain SC and Capasso F (1989) Ethnopharmacologic investigation of Ginger (Zingiber officinale). J Ethnopharmacol 17: 129–140

    Article  Google Scholar 

  20. Suekawa M, Ishige A, Yuasa K, Sudo K, Aburada M and Hosoya E (1984) Pharmacological studies on Ginger 1. Pharmacological actions of pungent constituents (6)-gingerol and (6)-shogaol. J Pharm Dyn 7: 836–848

    CAS  Google Scholar 

  21. Kiuchi F, Iwakami S, Shibuya M, Hanaoka F and Sankawa U (1992) Inhibition of Prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull 40: 387–391

    PubMed  CAS  Google Scholar 

  22. Srivastava KC (1984) Effect of aqueous extracts of onion, garlic and ginger on platelet aggregation and metabolism of arachidonic acid in the blood vascular system: In vitro study. Prostagland Leukotr Med 13: 227–235

    Article  Google Scholar 

  23. Srivastava KC (1984) Aqueous extracts of onion, garlic and ginger inhibit platelet aggregation and alter arachidonic acid metabolism. Biomed Biochem Acta 43: S 335–S 346

    CAS  Google Scholar 

  24. Srivastava KC (1986) Isolation and effects of some ginger components on platelet aggregation and eicosanoid biosynthesis. Prostagland Leukotr Med 25: 187–198

    Article  CAS  Google Scholar 

  25. Srivastava KC (1989) Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostagland Leukotr Med 35: 183–185

    Article  CAS  Google Scholar 

  26. Backon J (1986) Ginger: Inhibition of thromboxane synthetase and Stimulation of prostacyclin: relevance for medicine and psychiatry. Med Hypothes 20: 271–278

    Article  CAS  Google Scholar 

  27. Srivastava KC and Mustafa T (1989) Ginger (Zingiber officinale) and rheumatic disorders. Med Hypothes 29: 25–28

    Article  CAS  Google Scholar 

  28. Srivastava KC and Mustafa T (1992) Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypothes 39: 342–348

    Article  CAS  Google Scholar 

  29. Wei Y (1986) Shengjiang. In: Chang H-M, But PP-H (red) Pharmacology and Applications of Chinese Materia Medica Vol 1. Singapore: World Scientific pp 366–369

    Google Scholar 

  30. Backon J (1987) Use of a novel thromboxane synthetase inhibitor in burns. Burns 13: 252–254

    Article  CAS  Google Scholar 

  31. Leung AY (1988) Fresh Ginger juice in treatment of kitchen burns. Herbalgram No 16: 6

    Google Scholar 

  32. Yamahara J, Rong HQ, Iwamoto M, Kobayashi G, Matsuda H and Fujimura H (1989) Active components of Ginger exhibiting anti-serotonergic action. Phytotherapy Res 3: 70–71

    Article  CAS  Google Scholar 

  33. Maries RJ. Kaminski J. Arnason IT et al. (1992) A bioassay for inhibition of Serotonin release from bovine platelets. J Nat Prod 55: 1044–1056

    Article  Google Scholar 

  34. Mustafa T and Srivastava KC (1990) Ginger (Zingiber officinale) in migraine headache. J Ethnopharmacol 29: 267–273

    Article  PubMed  CAS  Google Scholar 

  35. Yamahara J. Miki K, Chisaka T et al. (1985) Cholagogic effect of Ginger and its active constituents. J Ethnopharmacol 13: 217–225

    Article  PubMed  CAS  Google Scholar 

  36. Hikino H, Kiso Y, Kato N et al. (1985) Antihepatotoxic actions of gingerols and diarylhepanoids. J Ethnopharmacol 14: 31–39

    Article  PubMed  CAS  Google Scholar 

  37. Gugral S, Bhumra H and Swaroop M (1987) Effect of Ginger (Zingiber officinale Roscoe) oleoresin on seram and hepatic cholesterol levels in cholesterol fed rats. Nutr Rep 17: 183–184

    Google Scholar 

  38. Giri J. Devi TKS and Meerarani S (1984) Effect of Ginger on serum cholesterol levels. Ind J Nutr Diet 21: 433–436

    CAS  Google Scholar 

  39. Sambaiah K and Srinivasan K (1989) Influence of spices and spice principles on hepatic mixed funetion oxygenase system in rats. Ind J Biochem Biophys 26: 254–258

    CAS  Google Scholar 

  40. Srinivasan K and Sambaiah K (1991) The effects of spices on cholesterol 7a hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Int J Vitam Nut Res 61: 364–369 [through Chem Abstr 116: 127559]

    CAS  Google Scholar 

  41. Babu PS, Srinivasan K (1993) Influence of dietary spices on adrenal steroidogenesis in rats. Nutr Res 13: 435–444

    Article  CAS  Google Scholar 

  42. Sakai K, Miyazaki Y, Yamane T, Taitoh Y, Ikawa C and Mishihata T (1989) Effect of extracts of Zingiberaceae herbs on gastric secretion in rabbits. Chem Pharm Bull 37: 215–217

    PubMed  CAS  Google Scholar 

  43. Yamahara J. Mochizuki M, Rong HQ, Matsuda H and Fujimura H (1988) The anti-ulcer effect in rats of Ginger constituents. J Ethnopharmacol 23: 299–304

    Article  PubMed  CAS  Google Scholar 

  44. Kawai T, Kinoshita K, Koyama K, Takahashi K (1994) Antiemetic principles of Magnolia obovata bark and Zingiber officinale rhizome. Planta Med 60: 17–20

    Article  PubMed  CAS  Google Scholar 

  45. Mowrey DB and Clayson DE (1982) Motion sickness, Ginger and psychophysics. Lancet i: 655–657

    Article  Google Scholar 

  46. Grontved A and Hentzer E (1986) Vertigo-reducing effect of Ginger root. A controlled clinical study. J Oto-Rhinolaryngol 48: 282–286

    CAS  Google Scholar 

  47. Grontved A, Brask T, Kambskard J and Hentzer E. (1988) Ginger root against seasickness. A controlled trial on the open sea. Acta Otolaryngol (Stockh) 105: 45–49

    Article  CAS  Google Scholar 

  48. Bone ME, Wilkinson DJ, Young JR, McNeil I, Charlton S (1990) Ginger root-a new antiemetic. The effect of Ginger root on postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 45: 669–671

    Article  PubMed  CAS  Google Scholar 

  49. Fischer-Rasmussen W, Kjaer SK, Dahl C and Asping U (1990) Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynaecol Reprod Biol 35: 19–24

    Google Scholar 

  50. Phillips S, Ruggier R, Hutchinson SE (1993) Zingiber officinale Ginger-an antiemetic for day case surgery. Anaesthesia 48: 715–717

    Article  PubMed  CAS  Google Scholar 

  51. Stott JRR, Hubble MP, Spense MB (1985) A double blind comparative trial of powdered Ginger root, Hyoscine hydrobromide and Cinnarizine in the prophylaxis of motion sickness induced by cross coupled Stimulation. Advisory Group for Aerospace Research and Development, Conference Proceedings 372, 39: 1–6

    Google Scholar 

  52. Wood CD, Manno JE, Wood MJ, Manno BR, Mims ME (1988) Comparison of efficacy of Ginger with various antimotion sickness drugs. Clin Res Pract Drag Reg Aff 6: 129–136

    Article  CAS  Google Scholar 

  53. Stewart JJ, Wood MJ, Wood CD, Mims ME (1991) Effects of Ginger on motion sickness susceptibility and gastric function. Pharmacology 42: 111–120

    Article  PubMed  CAS  Google Scholar 

  54. Bradley P (red) (1992) British Herbal Compendium. Volume I. Bournemouth: British Herbal Medicine Association pp 114–116

    Google Scholar 

  55. Adewunmi CO, Ogantimein BO, Furu P (1990) Molluscicidal and antischistosomal activities of Zingiber officinale. Planta Med 56: 374–376

    Article  PubMed  CAS  Google Scholar 

  56. Denyer CV, Jackson P, Loakes DM, Ellis MR, Young DAB (1994) Isolation of antirhinoviral sesquiterpenes from Ginger (Zingiber officinale). J Nat Prod 57: 658–662

    Article  PubMed  CAS  Google Scholar 

  57. Kawada T, Sakabe S-I, Watanabe T, Yamamoto M, Iwai K (1988) Some pungent principles of spices cause the adrenal medulla to secrete catecholamine in anaesthesised rats. Proc Soc Exp Biol Med 188: 229–233

    PubMed  CAS  Google Scholar 

  58. Kims B, Kang IH, Park YH (1987) DNA damage of lipid oxidation products and its inhibition mechanism. Han’guk Susan Hah-heochi 20: 419–430 [through Chem Abstr 109: 5390]

    Google Scholar 

  59. Huang JK, Wang CS and Chang WH (1981) Studies on the antioxidative activities of spices grown in Taiwan I. Chung-Kuo Hung Yeh Hua Hsueh Hui Chi 19: 200–207 [through Chem Abstr 97: 143289]

    CAS  Google Scholar 

  60. Anonymous (1993) Drug products containing active ingredients offered over the counter (OTC) for use as a smoking deterrent. Fed Reg 58: 31241

    Google Scholar 

  61. Ding G, Naora K, Hayashibara M, Katagiri Y, Kano Y, Iwamoto K (1991) Pharmacokinetics of [6]-gingerol after intravenous administration in rats. Chem Pharm Bull 39: 1612–1614

    PubMed  CAS  Google Scholar 

  62. Anonymous (1981) Flavouring Substances and Natural Sources of Flavourings. 3rd edn. Council of Europe Moulins-lès Mets, Maisonneuve

    Google Scholar 

  63. Emig HE (1931) The pharmacological action of Ginger. J Am Pharm Assoc 20: 114–116

    CAS  Google Scholar 

  64. Opdyke DLJ (1979) Ginger Oil. Food Cosmet Toxicol 12: 901–902

    Google Scholar 

  65. Scott PM, Kennedy BPC (1975) The analysis of spices and herbs for aflatoxins. Can Inst Food Sci Technol J 8: 124–125

    CAS  Google Scholar 

  66. Smith MI, Elvove E, Valaer PJ, Frazier WH and Mallory CE (1930) Pharmacological and chemical studies of the cause of the so-called Ginger paralysis. Preliminary Report. US Public Health Reports 45: 1703–1716

    Article  CAS  Google Scholar 

  67. Shoji N, Iwasa A, Takemoto T, Ishida Y, Ohizumi Y (1982) Cardiotonic principles of Ginger (Zingiber officinale Roscoe). J Pharm Sci 71: 1174–1175

    Article  PubMed  CAS  Google Scholar 

  68. Suekawa M, Aburada M, Hosoya E (1986) Pharmacological studies on Ginger II. Pressor action of (6)-shogaol in anaesthesised rats, or hindquarters, tail and mesenteric vascular beds of rats. J Pharmacobio-Dyn 9: 842–852

    PubMed  CAS  Google Scholar 

  69. Tulipan L (1938) Cosmetic irritants. Archs Derm Syph 38: 906

    CAS  Google Scholar 

  70. Stäger J. Wüthrich B, Johansson SGO (1991) Spice allergy in celery-sensitive patients. Allergy 46: 475–478

    Article  PubMed  Google Scholar 

  71. Futrell JM, Rietschel RL (1993) Spice allergy evaluated by results of patch tests. Cutis 52: 288–290

    PubMed  CAS  Google Scholar 

  72. Yamamato K (1960) Experimental study on Ginger ingestion: Dermatological study of spice ingestion. Igaku Kenkyu 30: 207–210

    Google Scholar 

  73. Liu PHW, Ho HL (1983) Ginger and drug bezoar induced small bowel obstruction. J Roy Coli Surg Edinburgh 28: 397–398

    CAS  Google Scholar 

  74. Awang DCV (1992) Ginger. Can Pharm J: 309–311

    Google Scholar 

  75. Desai HG, Kairo RH, Choksi AP (1990) Effect of ginger and garlic on DNA content of gastric aspirate. Ind J Med Res 92: 139–141

    CAS  Google Scholar 

  76. Haginawa J, Harada M, Morishita J (1963) Pharmacological studies on crude drugs VII. Properties of essential oil components of aromatics and their pharmacological effect on mouse intestine. Yakugaku Zasshi 93: 624–628 [through Chem Abstr 60: 999]

    Google Scholar 

  77. Huang Q, Matsuda H, Sakai K, Yamahara J, Tamai Y (1990) The effect of Ginger on serotonin-induced hypothermia and diarrhoea. Yakugaku Zasshi 110: 936–942

    PubMed  CAS  Google Scholar 

  78. Yamahara J. Huang Q, Li YH, Xul, Fujimura H (1990) Gastrointestinal motility enhancing effect of Ginger and its active constituents. Chem Pharm Bull 38: 430–431

    PubMed  CAS  Google Scholar 

  79. Phillips S, Hutchinson S, Ruggier R (1993) Zingiber officinale does not affect gastric emptying rate. A randomised, placebo controlled, crossover trial. Anaesthesia 48: 393–395

    Article  PubMed  CAS  Google Scholar 

  80. Backon J (1990) Ginger as an antiemetic: possible side effects due to its thromboxane synthetase activity. Anaesthesia 46: 705–706

    Article  Google Scholar 

  81. Verma SK, Singh J, Khamesra R, Bordia A (1993) Effect of ginger on platelet aggregation in man. Ind J Med Res Section B 98: 240–242

    CAS  Google Scholar 

  82. Lumb AB (1994) Effect of dried ginger on human platelet funetion. Thromb Haemostas 71: 110–111

    CAS  Google Scholar 

  83. Meghal SK, Nath MC (1962) Effect of spice diet on the intestinal synthesis of thiamine in rats. Ann Biochem Exp Med 22: 99–104 [through Chem Abstr 57: 11625]

    PubMed  CAS  Google Scholar 

  84. Rattanapanone V (1979) Antithiamin factor in fruits, mushrooms and spices. Chiang Mai Med Bull 18: 9–16 [through Chem Abstr 91: 191647]

    CAS  Google Scholar 

  85. Henry CJK, Piggott SM (1987) Effect of Ginger on metabolic rate. Hum Nutr Clin Nutr 41C: 89–92

    Google Scholar 

  86. Madaus G (1979) Lehrbuch der biologischen Heilmittel. Band 1-111. Hildesheim: Georg Olms Verlag, p. 2870

    Google Scholar 

  87. Sakai K, Oshima N et al. (1986) Pharmaceutical studies on crude drugs 1. Effect of the Zingiberaceae crude drug extracts on sulfaguanidine absorption from rat small intestine. Yakugaku Zasshi 106: 947–950

    PubMed  CAS  Google Scholar 

  88. Perry LM (1980) Medicinal plants of East and Southeast Asia. MIT Press Cambridge, pp. 443–444

    Google Scholar 

  89. Kada T, Morita K, Inowe T (1978) Anti-mutagenic action of vegetable factor(s) on the mutagenic principle of tryptophan pyrolysate. Mutat Res 53: 351–353

    PubMed  CAS  Google Scholar 

  90. Morita K, Hara M, Kada T (1978) Studies on natural desmutagens: Screening for vegetable and fruit factors active in inactivation of mutagenic pyrolysis produets from amino acids. Agric Biol Chem 42: 1235–1238

    Article  CAS  Google Scholar 

  91. Mamoru A (1978) Experimental urinary bladder cancer by bladder implantation of pellets containing Mioga extract, 1-arginine and piperidine. Tokyo Iikeikae Ika Daigaku Zasshi 93: 698–704 [through Chem Abstr 91: 50849]

    Google Scholar 

  92. Nakamura H, Yamamoto T (1982) Mutagen and anti-mutagen in Ginger, Zingiber officinale. Mutat Res 103: 119–126

    Article  PubMed  CAS  Google Scholar 

  93. Nakamura H, Yamamoto T (1983) The active part of the [6]-Gingerol molecule in mutagenesis. Mutat Res 122: 87–94

    Article  PubMed  CAS  Google Scholar 

  94. Morimoto L, Watanabe F, Osawa T, Okibsu T (1982) Mutagenicity Screening of crude drugs with Bacillus subtilis rec-assay and Salmonella/ microsome reversion assay. Mutat Res 97: 81–102

    PubMed  CAS  Google Scholar 

  95. Yamamoto H, Mizutani T, Nomura H (1982) Studies on the mutagenicity of crude drug extracts. I. Yakugaku Zasshi 102: 596–601

    PubMed  CAS  Google Scholar 

  96. Nagabhushan AI, Amonkar AJ, Bhide SV (1987) Mutagenicity of Gingeroi and Shogaol and antimutagenicity of Zingerenone in Salmonella/microsome assay. Cancer Lett 36: 221–223

    Article  PubMed  CAS  Google Scholar 

  97. Mahmoud J, Alkafahi A, Abdelaziz A (1992) Mutagenic an toxic activities of several spices and some Jordanian medicinal plants. Int J Pharmacognosy 30: 81–85

    Article  Google Scholar 

  98. Koba H, Hasegawa Y, Matsuoka A et al. (1988) Mutagenicity and deactivation of yellowtail products produced by cooking. Nippon Kasei Gakkaishi pp. 1105–1110 [through Chem Abst 110: 22440]

    Google Scholar 

  99. Kuroda K, Yoo YS, Ishibashi T (1989) Ree-Assay of natural food additives Part 2. Seikatsu Eisei 33: 15–23 [through Chem Abstr 111: 38126]

    CAS  Google Scholar 

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  1. D. Corrigan
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Editors and Affiliations

  1. Royal Dutch Association for the Advancement of Pharmacy, Alexanderstraat 11, 2514 JL, The Hague, The Netherlands

    Peter A. G. M. De Smet

  2. Bundesinstitut für Arzneimittel und Medizinprodukte, Seestraße 10, 13353, Berlin, Germany

    Konstantin Keller

  3. Westpreußenstraße 71, 81927, München, Germany

    Rudolf Hänsel

  4. College of Pharmacy, Dalhousie University, B3H3J5, Halifax, Canada

    R. Frank Chandler

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Corrigan, D. (1997). Zingiber Officinale. In: De Smet, P.A.G.M., Keller, K., Hänsel, R., Chandler, R.F. (eds) Adverse Effects of Herbal Drugs. Adverse Effects of Herbal Drugs, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60367-9_19

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