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The Production and Analysis of Helminth Excretory-Secretory (ES) Products

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Part of the book series: Springer Lab Manuals ((SLM))

Abstract

Parasitic helminths secrete and excrete a wide range of molecules during culture in vitro. Given the limitation of these culture conditions, one must presume that the molecules secreted have a biological function, and a role to play in maintaining the homeostasis of the host/parasite relationship. In the present chapter we have attempted to review the conditions already used to maintain a range of parasites considered to be of medical, economic and biological importance. In doing so, we have also attempted to draw the attention of the reader to some of the more chemically defined molecules found in culture supernates or excretory-secretory (ES) products. Particular importance has been placed on molecules considered to be essential to the maintenance of the life cycle of these parasites, as these molecules probably represent an “Achilles heel” of many of the parasite species described.

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Brown, A., Griffiths, G., Brophy, P.M., Furmidge, B.A., Pritchard, D.I. (1997). The Production and Analysis of Helminth Excretory-Secretory (ES) Products. In: Rogan, M.T. (eds) Analytical Parasitology. Springer Lab Manuals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60345-7_4

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