Abstract
Relief of obstructive jaundice by insertion of a biliary endoprosthesis consisting of a tube or metallic stent is an extremely useful palliative therapy for inoperable advanced malignant biliary strictures and has come to be widely employed (UCHIDA et al. 1975; YOSHIOKA et al. 1990). Since 1987 we have used metallic stents as biliary endoprostheses in approximately 200 patients with inoperable advanced malignant biliary strictures. However, to prevent tumor ingrowth into the metallic stent and to enhance the therapeutic results, antitumor treatment is needed, and recently a therapeutic effect has been achieved with the combination of radiation therapy and infusion chemotherapy.
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References
Buskirk SJ, Gunderson LL, Adson MA, et al (1984) Analysis of failure following curative irradiation of gallbladder and extrahepatic bile duct carcinoma.Int J Radiat Oncol Biol Phys 10: 2013–2023
Cameron JL, Broe P, Zuidema GD (1982) Proximal bile duct tumors.Ann Surg 196: 412–419
Falkson G, Maclntyre JM, Moertel C (1984) Eastern cooperative oncology group experience with chemotherapy for inoperable gallbladder and bile duct cancer.Cancer 54: 965–969
Fields JN, Emami B (1987) Carcinoma of the extrahepatic biliary system - results of primary and adjuvant radio-therapy.Int J Radiat Oncol Biol Phys 13: 331–338
Fletcher MS, Brinkley D, Dawson JL, et al (1983) Treatment of hilar carcinoma by bile drainage combined with internal radiotherapy using 192iridium wire.Br J Surg 70: 733–735
Fritz P, Brambs H, Schraube P, et al (1994) Combined external beam radiotherapy and intraluminal high dose rate brachytherapy on bile duct carcinomas.Int J Radiat Oncol Biol Phys 29: 855–861
Harvey JH, Smith FP, Schein PS (1984) 5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract. J Clin Oncol 2:1245–1248
Hendrickx P, Luska G, Junker D et al (1990) Ergebnisse der perkutan transluminal Bestrahlung von Gallenwegskarzinomen mit 192-iridium.Strahlenther Onkol 166: 392–396
Ikeda H, Kuroda C, Uchida H, et al (1979) Intraluminal irradiation with iridium-192 wires for extrahepatic bile duct carcinoma - a preliminary report.Nippon Acta Radiol 39: 1356–1358
Kajanti M, Pyrhonen S (1994) Epirubicin-sequential methotrexate-5-fluorouracil-leucovorin treatment in ad-vanced cancer of the extrahepatic biliary system.Am J Clin Oncol 17: 223–226
Maeda M, Timmermans HA, Uchida BT, et al (1992) In vitro comparison of the spiral z stent and the Gianturco z stent.J Vase Interv Radiol 3: 565–569
Oberfield RA, Rossi RL (1988) The role of chemotherapy in the treatment of bile duct cancer.World J Surg 12: 105–108
Okada S, Ishii H, Nose H, et al (1994) A phase II study of cisplatin in patients with biliary tract carcinoma.Oncology 51: 515–517
Smith JW, Bukowski RM, Hewlett JS, et al (1984) Hepatic artery infusion of 5-fluorouracil and mitomycin C in cho-langiocarcinoma and gallbladder carcinoma.Cancer 54: 1513–1516
Taal BG, Audisio RA, Bleiberg H, et al for the Gastrointestinal Tract Cancer Cooperative Group (1993) Phase II trial of mitomycin C in advanced gallbladder and biliary tree car-cinoma. An EORTC gastrointestinal tract cancer cooperative group study. Ann Oncol 4:607–609
Tamada T, Yoshimura H, Yoshioka T, et al (1991) High dose rate 60Co-RALS intraluminal radiation therapy for advanced biliary tract cancer with obstructive jaundice.J Jpn Soc Ther Radiol Oncol 3: 251–263
Tamada T, Yoshimura H, Iwata K, et al (1995) The influence of the metallic stent for irradiation - experimental study by phantom and normal bile duct of dogs.J Jpn Soc Ther Radiol Oncol 7: 39–46
Uchida H, Kuroda C, Nakamura H, et al (1975) Percutaneous external and internal drainage of biliary tract with special reference to technique and diagnostic evaluation of follow- up cholangiography.Nippon Acta Radiol 35: 53–67
Yoshimura H, Sakaguchi H, Tamada T, et al (1989) Afterloading intracavitary irradiation and expandable stent for malignant biliary obstruction.Radiat Med 7: 36–41
Yoshioka T, Sakaguchi H, Yoshimura H, et al (1990) Expandable metallic biliary endoprostheses: preliminary clinical evaluation.Radiology 177: 253–257
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© 1997 Springer-Verlag Berlin Heidelberg
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Yoshimura, H., Sakaguchi, H., Uchida, H. (1997). Endoluminal Radiation Therapy and Infusion Chemotherapy for Malignant Biliary Strictures. In: Rossi, P., Bezzi, M. (eds) Biliary Tract Radiology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60343-3_32
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DOI: https://doi.org/10.1007/978-3-642-60343-3_32
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-64363-7
Online ISBN: 978-3-642-60343-3
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