Skip to main content
SpringerLink
Log in
Book cover

Biliary Tract Radiology pp 141–157Cite as

Nuclear Medicine in Acute and Chronic Disorders of the Hepatobiliary Tree

  • Chapter

  • 183 Accesses

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

It is estimated that approximately 10%–15% of Americans have gallstones. Of these 20 million Americans (16 million female and 4 million male), 20%–25% will develop acute cholecystitis and 20%–35% will develop symptomatic chronic cholecystitis, while the remainder remain asymptomatic (Anderson 1971; Hardy 1988).

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Achong DM, Oates E (1994) A reversed sequence of gallbladder and small bowel visualization during cholescinti- graphy: its relationship to chronic cholecystitis. Clin Nucl Med 19: 89–92

    Article  PubMed  CAS  Google Scholar 

  • Anderson WHD (1971) Pathology. Mosby, St Louis, pp 1261–1265

    Google Scholar 

  • Andren-Sandberg A, Johansson S, Bengmark S (1991) Accidental lesion of the common bile duct at cholecystectomy. Ann Surg 201: 452–455

    Article  Google Scholar 

  • Anonymous (1993) Gallstones and laparoscopic cholecystectomy. JAMA 29: 1018–1024

    Google Scholar 

  • Balon HR, Nagle CE (1992) Computer-assisted imaging and display for biliary leak detection. Clin Nucl Med 17: 336–337

    Article  PubMed  CAS  Google Scholar 

  • Bar-Meir S, Halpern Z, Bardon E, et al (1984) Frequency of papillary stenosis among cholecystectomized patients. Hepatology 4: 328–330

    Article  PubMed  CAS  Google Scholar 

  • Bobba VR, Krishnamurthy GT, Kingson E, et al (1984) Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones (concise communication). J Nucl Med 25: 21–24

    PubMed  CAS  Google Scholar 

  • Bolen G, Javitt NB (1982) Biliary dyskinesia: mechanisms and management. Hosp Pract 17: 115–130

    CAS  Google Scholar 

  • Brugge W, Brand D, Atkins H, Lane B, Abel W (1986) Gallbladder dyskinesia in chronic acalculous cholecystitis. Dig Dis Sci 31: 461–467

    Article  PubMed  CAS  Google Scholar 

  • Bushnell DL, Perlman SC, Wilson MA, Polycr RD (1986) The rim sign: association with acute cholecystitis. J Nucl Med 27: 353–356

    PubMed  CAS  Google Scholar 

  • Camishion RD, Goldstein F (1967) Partial, noncalculous cystic duct obstruction (cystic duct syndrome). Surg Clin North Am 47: 1107–1114

    PubMed  CAS  Google Scholar 

  • Carichner SL, Nagle CE (1987) Hepatobiliary scintigraphy in patients with bile leaks. J Nucl Med Technol 15: 182–186

    Google Scholar 

  • Cecil B (1979) Textbook of medicine. Saunders, Philadelphia, pp 1624–1628

    Google Scholar 

  • Choy D, Shi EC, McLean RG, Hoschl R, Murry IPC, Ham JM (1984) Cholescintigraphy in acute cholecystitis: use of intravenous morphine. Radiology 151: 203–207

    PubMed  CAS  Google Scholar 

  • Coleman RE, Freitas JE, Fink-Bennett D, Bree RL (1984) The dilated cystic duct sign - a potential cause of false negative cholescintigraphy. Clin Nucl Med 9: 134–136

    Article  PubMed  CAS  Google Scholar 

  • Cozzolino HJ, Goldstein F, Greening RR, Wirts CW (1963) The cystic duct syndrome. JAMA 185: 100–104

    Google Scholar 

  • Cuschieri A, Dubois F, Mouiel J, Mouret P, Becker H, Buess G, Trede M, Troidl H (1991) The European experience with laparoscopic cholecystectomy. Am J Surg 161: 385–387

    Article  PubMed  CAS  Google Scholar 

  • Datz FL (1986) Utility of indium-lll-labeled leukocyte imaging in acute acalculous cholecystitis. AJR 147:813- 814

    Google Scholar 

  • Datz F (1988) Handbook in radiology, nuclear medicine. Mosby Yearbook, St Louis, pp 154–155

    Google Scholar 

  • DeRidder P, Fink-Bennett D (1984) The dilated common duct sign: a potential indicator of a sphincter of oddi dyskinesia. Clin Nucl Med 9: 262–263

    Article  PubMed  CAS  Google Scholar 

  • Donohue JH, Farnell MB, Grant CS, Van Heerden JA, Wahlstrom HE, Sarr MG, Weaver AL, Ilstup DM (1992) Laparoscopic cholecystectomy; early Mayo Clinic experience. Mayo Clin Proc 67: 449–455

    PubMed  CAS  Google Scholar 

  • Dubois F, Berthelot G, Levard H (1991) Laparoscopic cholecystectomy: historic perspective and personal experience. Surg Laparosc Endosc 1: 52–57

    PubMed  CAS  Google Scholar 

  • Eikman EA, Cameron JL, Coleman M, Natarajan TK, Dugal P, Wagner HN Jr (1975) A test for patency of cystic duct in acute cholecystitis. Ann Intern Med 82: 318–322

    PubMed  CAS  Google Scholar 

  • Fink-Bennett D (1985) The role of cholecystogogues in the evaluation of biliary tract disorders. In: Freeman LM, Weissman HS (eds) Nuclear medicine annual. Raven, New York

    Google Scholar 

  • Fink-Bennett D (1991) Augmented cholescintigraphy: its role in detecting acute and chronic disorders of the hepatobiliary tree. Semin Nucl Med 21: 128–139

    Article  PubMed  CAS  Google Scholar 

  • Fink-Bennett D, Balon H (1993) The role of morphine- augmented cholescintigraphy in the detection of acute cholecystitis. Clin Nucl Med 18: 891–897

    Article  PubMed  CAS  Google Scholar 

  • Fink-Bennett D, Freitas JE, Ripley SD, Bree RL (1985a) The sensitivity of hepatobiliary imaging and real-time ultrasonogrphy in the detection of acute cholecystitis. Arch Surg 120: 904–906

    PubMed  CAS  Google Scholar 

  • Fink-Bennett D, DeRidder P, Kolozsi W, Gordon RM, Rapp J (1985b) Cholecystokinin cholescintigraphic findings in the cystic duct syndrome. J Nucl Med 26: 1123–1128

    PubMed  CAS  Google Scholar 

  • Fink-Bennett D, Clark K, Tsai D, Nuechterlein P (1991a) Indium-Ill WBC imaging in acute cholecystitis. J Nucl Med 32: 803–804

    PubMed  CAS  Google Scholar 

  • Fink-Bennett D, Balon H, Robbins T, Tsai D (1991b) Morphine augmented cholescintigraphy: its efficacy in detecting acute cholecystitis. J Nucl Med 32: 1231–1233

    PubMed  CAS  Google Scholar 

  • Fink-Bennett D, DeRidder P, Kolozsi W, Gordon R, Jaros R (1991c) Cholecystokinin cholescintigraphy: detection of abnormal gallbladder motor function in patients with chronic acalculous gallbladder disease. J Nucl Med 32: 1695–1699

    PubMed  CAS  Google Scholar 

  • Freeman L, Sugarman L, Weissman H (1981) Role of cholecystokinetic agents in 99m-Tc-IDA cholescintigraphy. Semin Nucl Med 11: 186–193

    Article  PubMed  CAS  Google Scholar 

  • Freitas JE (1982) Cholescintigraphy in acute and chronic cholecystitis. Semin Nucl Med 12: 18–26

    Article  PubMed  CAS  Google Scholar 

  • Freitas JE, Rajinder M, Gulati MD (1980) Rapid evaluation of acute abdominal pain by hepatobiliary scanning. JAMA 244: 1585–1587

    Article  PubMed  CAS  Google Scholar 

  • Freitas JE, Coleman RE, Nagle CE, Bree RL, Krewer KD (1983) Influence of scan pathologic criteria on the specificity of cholescintigraphy (concise communication). J Nucl Med 24: 876–879

    PubMed  CAS  Google Scholar 

  • Gentili A, Gilkeson RC, Adler LP (1993) Scintigraphic detec-tion of bile leaks after laparoscopic cholecystectomy. Clin Nucl Med 18: 1–6

    Article  PubMed  CAS  Google Scholar 

  • Halverson JD, Garner BA, Siegel BA, Alexander R, Edundowicz SA, Sampbell W, Miller JE (1992) The use of hepatobiliary scintigraphy in patients with acalculous biliary colic. Arch Intern Med 152: 1305–1307

    Article  PubMed  CAS  Google Scholar 

  • Hardy JD (1988) Hardy’s textbook of surgery, 2nd edn. Lippincott, Philadelphia, pp 677–690

    Google Scholar 

  • Harrison TR, Adams RD, Bennett IL, et al (1966) Principles of internal medicine. McGraw-Hill, New York, pp 1088-1093 Harvey RF, Oliver JM (1980) Cholecystokinins and the gallbladder. Gastroenterology 78: 1117–1119

    Google Scholar 

  • Hawasli A, Lloyd LR (1991) Laparoscopic cholecystectomy: the learning curve: report of 50 patients. Am J Surg 57: 542–545

    CAS  Google Scholar 

  • Hogan W, Green J, Dodds I, et al (1982) Paradoxical response to cholecystokinin (CCK-OP) in patients with suspected sphincter-of-Oddi dysfunction (abstract). Gastroenterology 82: 1085

    Google Scholar 

  • Ivy AC, Oldbert E (1928) A hormone mechanism for gallblad-der contraction and evacuation. Am J Physiol 86: 599–613

    CAS  Google Scholar 

  • Jopes JE, Mutt V (1961) The gastrointestinal hormones, secretin and cholecystokinin-pancreomyzin. Ann Intern Med 55: 395–405

    Google Scholar 

  • Kane RA, Costello P, Duszlak E (1983) Computed tomography in acute cholecystitis: new observations. AJR 141: 697–701

    PubMed  CAS  Google Scholar 

  • Kaplun L, Weissman HS, Rosenblatt RR, Freeman LM (1985) The early diagnosis of common bile duct obstruction using cholescintigraphy. JAMA 254: 2431–2434

    Article  PubMed  CAS  Google Scholar 

  • Keller I A, Weissman HS, Kaplan LL, et al (1984) The use of water ingestion to distinguish the gallbladder and duodenum on cholescintigrams. Radiology 152: 151

    Google Scholar 

  • Keslar PJ, Turbiner EH (1987) Hepatobiliary imaging and the use of intravenous morphine. Clin Nucl Med 12: 592–596

    Article  PubMed  CAS  Google Scholar 

  • Kim EE, Pjura G, Lowry P, Nguyen M, Pollack M (1986) Mor-phine-augmented cholescintigraphy in the diagnosis of acute cholecystitis. AJR 147: 1177–1179

    PubMed  CAS  Google Scholar 

  • Kim CK, et al (1990) Delayed biliary-to-bowel transit in cholescintigraphy after cholecystokinin treatment. Radiology 176: 533–556

    Google Scholar 

  • Krishnamurthy S, Krishnamurthy K (1988) Quantitative as-sessment of hepatobiliary diseases with Tc99m-IDA scintigraphy. In: Freeman LM, Weissman HS (eds) Nuclear Medicine Annual. Raven, New York, pp 309–313

    Google Scholar 

  • Krishnamurthy GT, Bobba VR, Kingston E (1981) Radionuclide ejection fraction: a technique for quantitative analysis of motor function of the human gallbladder. Gastroenterology 80: 482–490

    PubMed  CAS  Google Scholar 

  • Krishnamurthy GT, Bobba VR, McConnell D, et al (1983) Quantitative biliary dynamics: introduction of a new noninvasive scintigraphic technique. J Nucl Med 24: 217–3

    PubMed  CAS  Google Scholar 

  • Lechin F, Van Der Dijs B, Bentolila A, Pena F (1978) Adrener-gic influences on the gallbladder emptying. Am J Gastroenterol 69: 662–668

    PubMed  CAS  Google Scholar 

  • Lette J, Morin M, Heyen F, Paquet A, Levasseur A (1990) Standing views to differentiate gallbladder or bile leak from duodenal activity on cholescintigrams. Clin Nucl Med 15: 231–236

    Article  PubMed  CAS  Google Scholar 

  • McFarland JO, Currin J (1965) Cholecystokinin and the cystic duct syndrome. Clinical experience in a community hospital. Am J Gastroenterol 515–522

    Google Scholar 

  • Meyers WC, Branum GD, Farduk M, et al (1991) A prospective analysis of 1518 laparoscopic cholecystectomies. N Engl J Med 324: 1073–1078

    Article  Google Scholar 

  • Miller DR, Egbert RM, Braunstein P (1984) Comparison of ultrasound and hepatobiliary imaging in the early detection of acute total common bile duct obstruction. Arch Surg 119: 1233–1237

    PubMed  CAS  Google Scholar 

  • Mishra DC, Blooson GB, Fink-Bennett DF, Glover JJ (1991) Results of surgical therapy for biliary dyskinesia. Arch Surg 26: 957–959

    Google Scholar 

  • Morley JE (1982) The ascent of cholecystokinin (CCK)–from gut to brain. Life Sci 30: 479 - 493

    Article  PubMed  CAS  Google Scholar 

  • Moss AA, Gamsu G, Genant HK (1983) Computed tomography of the body. Saunders, Philadelphia, pp 14–18, 691–697

    Google Scholar 

  • Nagle CE, Fink-Bennett D, Freitas JE (1985) Bile ascites in adults: diagnosis using hepatobiliary scintigraphy. Clin Nucl Med 10: 403–405

    Article  PubMed  CAS  Google Scholar 

  • Newman P, Browne MK, Mowat W (1983) A simple technique for quantitative cholecystokinin-HIDA scanning. Br J Radiol 56: 500–502

    Article  PubMed  CAS  Google Scholar 

  • Pickelman J, Peiss R, Henkin R, et al (1985) The role of sincalide cholescintigraphy in the evaluation of patients with acalculous gallbladder disease. Arch Surg 120: 693–697

    Google Scholar 

  • Rayter Z, Tonge C, Bennett CE, Robinson PS, Thomas MH (1989) Bile leaks after simple cholecystectomy. Br J Surg 76: 1046–1048

    Article  PubMed  CAS  Google Scholar 

  • Rhoads JE, Allen JG, Harkins HN, Moyer CA (1970) Surgery: principles and practice. Saunders, Philadelphia Samuels BI, Freitas JE, Bree RL, Schwab RE, Heller ST (1983) A comparison of radionuclide hepatobiliary imaging and real-time ultrasound for the detection of acute cholecystitis. Radiology 147: 207–210

    Google Scholar 

  • Shaffer PB, Olsen JO (1982) Differentiation of the gallbladder from the duodenum on cholescintigrams by dynamic display. Radiology 145: 217

    PubMed  CAS  Google Scholar 

  • Shih WJ, Magoun S, Mills BJ, Pulmano C (1993) Bile leak from gallbladder perforation mimicking bowel activity and a false-negative result in a morphine-augmented choles-cintigraphy. J Nucl Med 33: 131–133

    Google Scholar 

  • Siddiqui AR, Ellis JH, Madura JA (1986) Different patterns for bile leakage following cholecystectomy demonstrated by hepatobiliary imaging. Clin Nucl Med 11: 751–753

    Article  PubMed  CAS  Google Scholar 

  • Sostre S, Kalloo A, Speigler E, Camaigo E, Wagner H (1992) A noninvasive test of sphincter of Oddi dysfunction in post cholecystectomy patients: the scintigraphic score. J Nucl Med 33: 1216–1222

    PubMed  CAS  Google Scholar 

  • Steinberg WM (1988) Sphincter of Oddi dysfunction: a clinical controversy. Gastroenteroloy 95: 1409–1415

    CAS  Google Scholar 

  • Vasques TE, Greenspan G, Evans DG, Halpern SE, Ashburn WL (1988) Clinical efficacy of intravenous morphine administration in hepatobiliary imaging for acute cholecystitis. Clin Nucl Med 13: 4–6

    Article  Google Scholar 

  • Walker AT, Shapiro AW, Brooks DC, Braver JM, Tumeh SS (1992) Bile duct disruption and biloma after laparoscopic cholecystectomy: imaging evaluation. AJR 158: 785–789

    PubMed  CAS  Google Scholar 

  • Weissman H (1981) The clinical role of technetium-99m iminodiacetic acid cholescintigraphy. In: Freeman LM, Weissman HS (eds) Nuclear medicine annual. Raven, New York, pp 35–90

    Google Scholar 

  • Yap L, Wycherley AG, Morphett AD, Toouli J (1991) Acalculous biliary pain: cholecystectomy alleviates symptoms in patients with abnormal cholescintigraphy. Gastroenterology 101: 786–793

    PubMed  CAS  Google Scholar 

  • Zech ER, Simmons LB, Kendrick RR, Soballe PW, Olcese JAM, Goff WB, II, Lawrence DP, DeWeese RA (1991) Cholecystokinin enhanced hepatobiliary scanning with ejection fraction calculation as an indicator of disease of the gallbladder. Surg Gynecol Obstet 172: 21–22

    PubMed  CAS  Google Scholar 

  • Zeissman H, Fahey F, Hilson, D (1992) Calculation of a gallbladder ejection fraction: advantage of continuous sincalide infusion over the three-minute infusion method. J Nucl Med 33: 537–541

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, William Beaumont Hospital, 3601 West 13 Mile Road, Royal Oak, MI, 48073-6769, USA

    D. Fink-Bennett MD & H. Balon MD

Authors
  1. D. Fink-Bennett MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Balon MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Radiology, University of Rome “La Sapienza”, Policlinico Umberto I, 00161, Rome, Italy

    Plinio Rossi MD (Professor and Chairman) & Mario Bezzi MD (Assistant Professor) (Professor and Chairman) &  (Assistant Professor)

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Fink-Bennett, D., Balon, H. (1997). Nuclear Medicine in Acute and Chronic Disorders of the Hepatobiliary Tree. In: Rossi, P., Bezzi, M. (eds) Biliary Tract Radiology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60343-3_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-60343-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64363-7

  • Online ISBN: 978-3-642-60343-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation