Abstract
Survival in untreated patients with metastatic carcinoma of the bladder is poor, the median survival being 3 months (Babaian et al. 1980). The current therapy of choice is combination chemotherapy, which is given with palliative intent, although some long-term survivors have been reported after achieving a complete response on chemotherapy. No clinical trials have been performed on treatment with chemotherapy versus best supportive care. Nevertheless, results from studies on prognostic factors and from phase III clinical trials support a beneficial effect of chemotherapy on survival in metastatic urothelial cancer. In most studies, data on urothelial cancer from different localizations have been clustered, as no differences in prognosis seem to exist between them.
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Van Der Rijt, C.C.D., Splinter, T.A.W. (1998). Management of Patients with Metastatic Carcinoma of the Bladder. In: Petrovich, Z., Baert, L., Brady, L.W. (eds) Carcinoma of the Bladder. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60258-0_28
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DOI: https://doi.org/10.1007/978-3-642-60258-0_28
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