Skip to main content

Risikofaktoren der Alzheimer-Krankheit

  • Chapter
Psychiatrie der Gegenwart 4
  • 59 Accesses

Zusammenfassung

Da es sich bei der Alzheimer-Demenz um eine Erkrankung handelt, die wahrscheinlich durch ein mehrjähriges, möglicherweise jahrzehntelanges, präklinisches, neuropathologisches Vorlaufstadium gekennzeichnet ist, könnte die genaue Kenntnis von spezifischen Risikofaktoren sowohl zur Frühdiagnose der Alzheimer-Demenz, als auch zur Abschätzung der individuellen Prognose beitragen. Die Reduktion spezifischer Risikofaktoren könnte dann ein wichtiger Baustein einer multifaktoriell orientierten Therapie werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Basun H, Forssel LG, Wetterberg L, Winblad B (1991) Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer’s disease. J Neural Transm 4: 231–258

    Google Scholar 

  • Breteler MMB, Duijn MC van, Chandra V et al. (1991) Medical history and the risk of Alzheimer’s disease: a collaborative re-analysis of case-control studies. Int J Epidemiol 20(Suppl 2): S36–S42

    Google Scholar 

  • **Canadian Study of Health and Aging (1994) Neurology 44: 2073– 2080

    Google Scholar 

  • Devanand DP, Sano M, Tang MX et al. (1996) Depressed mood and the incidence of Alzheimer’s disease in the elderly living in the community. Arch Gen Psychiatry 53: 175–182

    PubMed  CAS  Google Scholar 

  • Duijn CM van, Clayton D, Chandra V et al. (1991) Familial aggregation of Alzheimer’s disease and related disorders: A collaborative re-analysis of case-control studies. Int J Epidemiol 20(Suppl 2): S13–S20

    PubMed  Google Scholar 

  • **Duijn CM van, Clayton DG, Chandra V et al. (1994) Interaction between genetic and environmental risk factors for Alzheimer’s disease. Genet Epidemiol 11: 539–551

    Article  PubMed  Google Scholar 

  • Graves AB, Duijn CM van, Chandra V et al. (1991) Alcohol and tobacco consumption as risk factors for Alzheimer’s disease. Int J Epidemiol 20(Suppl 2): S48–S57

    PubMed  Google Scholar 

  • Hirst C, Yee IML, Sadovnick AD (1994) Familial risks for Alzheimer disease from a population-based series. Genet Epidemiol 11: 365–374

    Article  PubMed  CAS  Google Scholar 

  • Hofman A, Ott A, Breteler MMB et al. (1997) Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer’s disease in the Rotterdam Study. Lancet 349(9046): 152–154

    Article  Google Scholar 

  • Jorm AF, Duijn CM van, Chandra V et al. (1991) Psychiatric history and related exposures as risk factors for Alzheimer’s disease: a collaborative re–analysis of case– control studies. Int J Epidemiol 20(Suppl 2): S43–S47

    PubMed  Google Scholar 

  • *Kral V, Emery O (1989) Long term follow-up of depressive pseudode-mentia. Can J Psychiatry 34: 445–447

    PubMed  CAS  Google Scholar 

  • Kukull WA, Larson EB, Bowen JD et al. (1995) Solvent exposure as a risk factor for Alzheimer’s disease. Am J Epidemiol 141: 1059–1071

    PubMed  CAS  Google Scholar 

  • *Li G, Silverman JM, Smith CJ et al. (1995) Age at onset and familial risk in Alzheimer’s disease. Am J Psychiatry 152: 424–430

    PubMed  CAS  Google Scholar 

  • Martyn CN, Osmond C, Edwardson JA, Barker DJP, Harris EC, Lacey RF (1989) Geographical relation between Alzheimer’s disease and aluminium in drinking water. Lancet 1(8629): 59–62

    PubMed  CAS  Google Scholar 

  • Mayeux R, Ottmann R, Maestre G et al. (1995) Synergestic effects of traumatic head injury and apolipoprotein-E4 in patients with Alzheimer’s disease. Neurology 45: 555–557

    PubMed  CAS  Google Scholar 

  • McKenzie JE, Gentleman SM, Roberts GW, Graham DI, Royston MC (1994) Increased numbers of beta APP-immunoreactive neurones in the entorhinal cortex after head injury. Neuroreport 6/1: 161–4

    Article  PubMed  CAS  Google Scholar 

  • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 34/7: 939–944

    PubMed  CAS  Google Scholar 

  • Mortimer JA, Duijn CM van, Chandra V et al. (1991) Head trauma as a risk factor for Alzheimer’s disease: a collaborative re-analysis of case-control studies. Int J Epidemiol 20(Suppl 2): S28–S35

    PubMed  Google Scholar 

  • Nicolini M, Zatta PF, Corain B (eds) (1991) Aluminium in chemistry, biology and medicine. A series of advances, vol 1. Raven, New York

    Google Scholar 

  • **Ott A, Breteler MMB, van Harskamp F, Claus JJ, Cammen TJM van der, Grobbee DE, Hofman A (1995) Prevalence of Alzheimer’s disease and vascular dementia: association with education. Br Med J 310: 970–973

    CAS  Google Scholar 

  • Prince M, Cullen M, Mann A (1994) Risk factors for Alzheimer’s disease and dementia: a case-control study based on the MRC elderly hypertension trial. Neurology 44: 97–104

    PubMed  CAS  Google Scholar 

  • Rasmusson DX, Brandt J, Martin DB, Folstein MF (1995) Head injury as a risk factor in Alzheimer’s disease. Brain Injury 9: 213–219

    Article  PubMed  CAS  Google Scholar 

  • Rocca WA, Duijn CM van, Clayton D et al. (1991) Maternal age and Alzheimer’s disease: a collaborative re-analysis of case-control studies. Int J Epidemiol 20(Suppl 2): S21–S27

    PubMed  Google Scholar 

  • Snowdon DA, Kemper SJ, Mortimer JA, Greiner LH, Wekstein DR, Markesbery WR (1996) Linguistic ability in early life and cognitive function and Alzheimer’s disease in late life — Findings from the Nun Study. JAMA 275/7: 528–532

    Article  PubMed  CAS  Google Scholar 

  • *Stern Y, Tang MX, Denaro J, Mayeux R (1995) Increased risk of mortality in Alzheimer’s disease patients with more advanced educational and occupational attainment. Ann Neurol 37: 590–595

    Article  PubMed  CAS  Google Scholar 

  • Yoshitake T, Kiyohara Y, Kato I et al. (1995) Incidence and risk factors of vascular dementia and Alzheimer’s disease in a defined elderly Japanese population: the Hisayama Study. Neurology 45: 1161–1168

    PubMed  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hock, C., Müller-Spahn, F. (1999). Risikofaktoren der Alzheimer-Krankheit. In: Psychiatrie der Gegenwart 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60175-0_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-60175-0_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64291-3

  • Online ISBN: 978-3-642-60175-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics