Zusammenfassung
Der komplexe Heilungsprozeß von Wunden ist von zwei Komponenten abhängig, der Matrixsynthese und der Angiogenese. Insbesondere vascular endothelial growth factor (VEGF), insulin-like growth factor-I (IGF-I), fibroblast growth factor (FGF) und transforming growth factor-beta (TGF-β) nehmen eine zentrale Rolle bei der Regulation der Wundheilung ein. TGF-β und IGF-I stimulieren die Kollagensynthese. Kollagen wird für die Blutgefäßbildung benötigt [3] sowie für die Gewebsreparation.
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© 1999 Springer-Verlag Berlin Heidelberg
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Wagner, S. et al. (1999). Transforming growth factor-beta (TGF-β) und Insulin-like growth factor-I (IGF-I) in Wunden bei chirurgischen Patienten. In: Rühland, D., Rothmund, M., Hartel, W., Beger, H.G. (eds) Chirurgisches Forum ’99 für experimentelle und klinische Forschung. Deutsche Gesellschaft für Chirurgie, vol I/99. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60133-0_30
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DOI: https://doi.org/10.1007/978-3-642-60133-0_30
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