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Gastroduodenal Disease and Helicobacter pylori pp 237–260Cite as

Economic Perspectives in the Management of Helicobacter pylori Infections

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 241))

Abstract

The infection with Helicobacter pylori contributes to the occurrence of at least four diseases, that is, gastric ulcer, duodenal ulcer, gastric cancer and gastric mucosa-associated lymphoma tissue lymphoma. Many gastroenterologists believe that infection with H. pylori can also result in epigastric symptoms and nonulcer dyspepsia. The health economics of H. pylori infection relates to the cost-benefit relationship of preventing, treating or curing these various conditions through medical measures directed against the infectious organism. In addition, economic analyses have addressed various other aspects of diagnosis and management of patients infected with H. pylori. A minority of analyses were based on real data generated from prospective clinical trials or retrospective analysis of utilization of health care resources, while the majority of studies used economic modeling to predict the influence of various medical measures. The models used mostly decision trees, Markov chains, the declining exponential approximation of life expectancy (DEALE), and the accounting technique of net present value. The following three sections of the present chapter are focused towards the management of the three most common conditions associated with H. pylori, that is, peptic ulcer, gastric cancer, and nonulcer dyspepsia. In a subsequent section we discuss the workup of patients with upper abdominal symptoms and a few other economic issues related to the management of patients infected with H. pylori.

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Authors and Affiliations

  1. Gastroenterology Section, Department of Veterans Affairs, Medical Center 111F, 2100 Ridgecrest Drive SE, Albuquerque, NM, 87108, USA

    A. Sonnenberg & J. M. Inadomi

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  1. A. Sonnenberg
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  2. J. M. Inadomi
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Editors and Affiliations

  1. Medical Service (111), Central Texas Veterans Health Care System, Texas A&M University, College of Medicine, 1901 S. First Street, Temple, TX, 76504, USA

    T. Ulf Westblom M.D. (Chief) (Chief)

  2. Department of Pediatrics, Division of Pediatric Gastroenterology, Rainbow Babies and Children Hospital, Case Western Reserve University, 2074 Abington Road, Cleveland, OH, 44106, USA

    Steven J. Czinn M.D.

  3. Institute of Pathology, Case Western Reserve University, Biomedical Research Building, Rm. 919, 10900 Euclid Avenue, Cleveland, OH, 44106-4943, USA

    John G. Nedrud Ph.D. (Associate Professor) (Associate Professor)

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© 1999 Springer-Verlag Berlin Heidelberg

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Sonnenberg, A., Inadomi, J.M. (1999). Economic Perspectives in the Management of Helicobacter pylori Infections. In: Westblom, T.U., Czinn, S.J., Nedrud, J.G. (eds) Gastroduodenal Disease and Helicobacter pylori . Current Topics in Microbiology and Immunology, vol 241. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60013-5_12

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  • DOI: https://doi.org/10.1007/978-3-642-60013-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64221-0

  • Online ISBN: 978-3-642-60013-5

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