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Vaccines pp 171–200Cite as

Herpes

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 133))

Abstract

Of the nearly 100 herpes viruses that have been described, host species include primates, other mammals such as swine and horse as well as birds and fish R(oizman and Sears 1996), indicating a long coevolution of this virus family and animal life. A typical herpesvirus consists of a core containing a linear, double-stranded DNA of 150–230 kb, an icosahedral capsid of 162 capsomeres (100–110 nm in diameter), a surrounding amorphous material (the tegument), and an envelope derived from the cellular membrane and containing viral glycoprotein spikes R(OIZMAN and SEARS 1996).

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References

  • Ades AE, Peckham CS, Dale GE, Best JM, Jeansson S (1989) Prevalence of antibodies to herpes simplex virus types 1 and 2 in pregnant women, and estimated rates of infection. J Epidemiol Community Health 43:53–60

    Article  PubMed  CAS  Google Scholar 

  • Adler SP (1995) Immunoprophylaxis against cytomegalovirus disease. Scand J Infect Dis Suppl 99:105–109

    PubMed  CAS  Google Scholar 

  • Adlish JD, Lahijani RS, St Jeor SC (1990) Identification of a putative cell receptor for human cytomegalovirus. Virology 176:337–345

    Article  PubMed  CAS  Google Scholar 

  • Adour KK, Byl FM, Hilsinger RL Jr, Kahn ZM, Sheldon MI (1978) The true nature of Bell’s palsy: analysis of 1000 consecutive patients. Laryngoscope 88:787–801

    PubMed  CAS  Google Scholar 

  • Adour KK, Hilsinger Jr RL, Byl FM (1980) Herpes simplex polyganglionitis. Otolaryngol Head Neck Surg 88:270–274

    PubMed  CAS  Google Scholar 

  • Ahlfors K, Ivarsson SA, Johnsson T, Svensson I (1978) Congenital and acquired cytomegalovirus infections. Virological and clinical studies on a Swedish infant population. Acta Paediatr Scand 67:321–328

    Article  PubMed  CAS  Google Scholar 

  • Ahn K, Meyer TH, Uebel S, Sempe P, Djaballah H, Yang Y, Peterson PA, Fruh K, Tampe R (1996) Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J 15:3247–3255

    PubMed  CAS  Google Scholar 

  • Allen EM, Weir JP, Martin S, Mercadal C, Rouse BT (1990) Role of coexpression of IL-2 and herpes simplex virus proteins in recombinant vaccinia virus vectors on levels of induced immunity. Viral Immunol 3:207–215

    Article  PubMed  CAS  Google Scholar 

  • Andersson J (1996) EBV, Everybody’s virus: the management of Epstein-Barr virus infection. Herpes 3:55–62

    Google Scholar 

  • Arnold JC, Portmann BC, O’Grady JG, Naoumov NV, Alexander GJ, Williams R (1992) Cytomegalovirus infection persists in the liver graft in the vanishing bile duct syndrome. Hepatology 16:285–292

    Article  PubMed  CAS  Google Scholar 

  • Baringer JR (1996) Herpes simplex virus and Bell palsy (editorial; comment). Ann Intern Med 124:63–65

    PubMed  CAS  Google Scholar 

  • Baringer JR, Pisani P (1994) Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 36:823–829

    Article  PubMed  CAS  Google Scholar 

  • Baringer JR, Swoveland P (1973) Recovery of herpes-simplex virus from human trigeminal ganglions. N Engl J Med 288:648–650

    Article  PubMed  CAS  Google Scholar 

  • Barnes PD, Grundy JE (1992) Down-regulation of the class I HLA heterodimer and beta 2-microglobulin on the surface of cells infected with cytomegalovirus. J Gen Virol 73:2395–2403

    Article  PubMed  CAS  Google Scholar 

  • Bastian FO, Rabson AS, Yee CL, Tralka TS (1972) Herpesvirus hominis: isolation from human trigeminal ganglion. Science 178:306–307

    Article  PubMed  CAS  Google Scholar 

  • Beersma MF, Bijlmakers MJ, Ploegh HL (1993) Human cytomegalovirus down- regulates HLA class I expression by reducing the stability of class I H chains. J Immunol 151:4455–4464

    PubMed  CAS  Google Scholar 

  • Bergstrom T, Andersen O, Vahlne A (1989) Isolation of herpes simplex virus type 1 during first attack of multiple sclerosis. Ann Neurol 26:283–285

    Article  PubMed  CAS  Google Scholar 

  • Bergstrom T, Vahlne A, Alestig K, Jeansson S, Forsgren M, Lycke E (1990) Primary and recurrent herpes simplex virus type 2-induced meningitis. J Infect Dis 162:322–330

    Article  PubMed  CAS  Google Scholar 

  • Bernstein DI, Lee FK, Echler G, Nahmias AJ (1989) Clinical and serological outcome of genital herpes simplex virus (HSV) type 2 inoculation following oral HSV type 1 infection in guinea-pigs. J Gen Virol 70:2365–2372

    Article  PubMed  Google Scholar 

  • Beswick TSL (1962) The origin and the use of the word herpes. Med Hist 6:214–232

    PubMed  CAS  Google Scholar 

  • Blyth WA, Harbour DA, Hill TJ (1984) Pathogenesis of zosteriform spread of herpes simplex virus in the mouse. J Gen Virol 65:1477–1486

    Article  PubMed  Google Scholar 

  • Borysiewicz LK, Hickling JK, Graham S, Sinclair J, Cranage MP, Smith GL, Sissons JG (1988) Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses. J Exp Med 168: 919–931

    Article  PubMed  CAS  Google Scholar 

  • Bourne N, Milligan GN, Schleiss MR, Bernstein DI, Stanberry LR (1996) DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2. Vaccine 14:1230–1234

    Article  PubMed  CAS  Google Scholar 

  • Brehm MA, Bonneau RH, Knipe DM, Tevethia SS (1997) Immunization with a replication-deficient mutant of herpes simplex virus type 1 (HSV-1) induces a CD8+ cytotoxic T-lymphocyte response and confers a level of protection comparable to that of wild-type HSV-1. J Virol 71:3534–3544

    PubMed  CAS  Google Scholar 

  • Britt WJ, Ahlford CA (1996) Cytomegalovirus. In: Fields BN (ed) Fields virology. Lippincott-Raven, New York, pp 2493–22524

    Google Scholar 

  • Britt WJ, Vugler L, Stephens EB (1988) Induction of complement-dependent and - independent neutralizing antibodies by recombinant-derived human cytomegalovirus gp55–116 (gB). J Virol 62:3309–3318

    PubMed  CAS  Google Scholar 

  • Bruggeman CA, van Dam Mieras MC (1991) The possible role of cytomegalovirus in atherogenesis. Prog Med Virol 38:1–26

    PubMed  CAS  Google Scholar 

  • Buchman TG, Roizman B, Nahmias AJ (1979) Demonstration of exogenous genital reinfection with herpes simplex virus type 2 by restriction endonuclease fingerprinting of viral DNA. J Infect Dis 140:295–304

    Article  PubMed  CAS  Google Scholar 

  • Cai WH, Gu B, Person S (1988) Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion. J Virol 62:2596–2604 [published erratum appears in J Virol 1988, 62(11):4438]

    Google Scholar 

  • Campadelli Fiume G, Arsenakis M, Farabegoli F, Roizman B (1988) Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus. J Virol 62:159–167 Campadelli Fiume G, Stirpe D, Boscaro A, Avitabile E, Foa Tornasi L, Barker D, Roizman B (1990) Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection. Virology 178:213–222

    PubMed  CAS  Google Scholar 

  • Campadelli Fiume G, Stirpe D, Boscaro A, Avitabile E, Foa Tomasi L, Barker D, Roizman B (1990) Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection. Virology 178:213–222

    Article  PubMed  CAS  Google Scholar 

  • Chatterjee S, Koga J, Whitley RJ (1989) A role for herpes simplex virus type 1 glycoprotein E in induction of cell fusion. J Gen Virol 70:2157–2162

    Article  PubMed  CAS  Google Scholar 

  • Chee MS, Bankier AT, Beck S, Bohni R, Brown CM, Cerny R, Horsnell T, Hutchison CA 3d, Kouzarides T, Martignetti JA et al (1990) Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. In: McDougall JK (ed) Cytomegaloviruses. Springer, Berlin Heidelberg New York, pp 125–169 (Current topics in microbiology and immunology, vol 154 )

    Google Scholar 

  • Chen F, Zou JZ, di Renzo L, Winberg G, Hu LF, Klein E, Klein G, Ernberg I (1995) A subpopulation of normal B cells latently infected with Epstein-Barr virus resembles Burkitt lymphoma cells in expressing EBNA-1 but not EBNA-2 or LMP1. J Virol 69:3752–3758

    PubMed  CAS  Google Scholar 

  • Chou J, Kern ER, Whitley RJ, Roizman B (1990) Mapping of herpes simplex virus-l neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 250: 1262–1266

    Google Scholar 

  • Chou J, Kern ER, Whitley RJ, Roizman B (1990) Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 250:1262–1266

    Article  PubMed  CAS  Google Scholar 

  • Clements GB, Subak Sharpe JH (1988) Herpes simplex virus type 2 establishes latency in the mouse footpad. J Gen Virol 69:375–383

    Article  PubMed  Google Scholar 

  • Clements GB, Jamieson FE (1989) Reactivation of latent herpes simplex virus-1 (HSV) from mouse footpad cells demonstrated by in situ hybridization. Arch Virol 104:95–106

    Article  PubMed  CAS  Google Scholar 

  • Compton T, Nowlin DM, Cooper NR (1993) Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate. Virology 193:834–841

    Article  PubMed  CAS  Google Scholar 

  • Cook ML, Stevens JG (1973) Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intraaxonal transport of infection. Infect Immun 7:272–288

    PubMed  CAS  Google Scholar 

  • Cook ML, Bastone WB, Stevens JG (1974) Evidence that neurons harbor latent herpes simplex virus. Infect Immun 9:946–951

    PubMed  CAS  Google Scholar 

  • Corey L, Spear PG (1986) Infections with herpes simplex viruses (2). N Engl J Med 314:749–757

    Article  PubMed  CAS  Google Scholar 

  • Corey L, Adams HG, Brown ZA, Holmes KK (1983) Genital herpes simplex virus infections: clinical manifestations, course, and complications. Ann Intern Med 98:958–972

    PubMed  CAS  Google Scholar 

  • Craig CP, Nahmias AJ (1973) Different patterns of neurological involvement with herpes simplex virus types 1 and 2: isolation of herpes simplex virus type 2 from the buffy coat of two adults with meningitis. J Infect Dis 127:365–372

    Article  PubMed  CAS  Google Scholar 

  • Cushing H (1905) Surgical aspect of major neuralgia of trigeminal nerve: report of 20 cases of operation upon the gasserian ganglion with anatomic and physiological notes on the consequence of its removal. JAMA 44:1002–1008

    Google Scholar 

  • Diamond DJ, York J, Sun JY, Wright CL, Forman SJ (1997) Development of a candidate HLA A*0201 restricted peptide-based vaccine against human cytomegalovirus infection. Blood 90:1751–1767

    PubMed  CAS  Google Scholar 

  • Dix RD, Waitzman DM, Follansbee S, Pearson BS, Mendelson T, Smith P, Davis RL, Mills J (1985) Herpes simplex virus type 2 encephalitis in two homosexual men with persistent lymphadenopathy. Ann Neurol 17:203–206

    Article  PubMed  CAS  Google Scholar 

  • Dobbins JG, Stewart JA, Demmler GJ (1992) Surveillance of congenital cytomegalovirus disease, 1990–1991. Collaborating Registry Group. MMWR CDC Surveill Summ 41:35–39

    PubMed  CAS  Google Scholar 

  • Edstrom S, Hanner P, Andersen O, Rosenhall U, Vahlne A, Karlsson B (1987) Elevated levels of myelin basic protein in CSF in relation to auditory brainstem responses in Bell’s palsy. Acta Otolaryngol (Stockh) 103:198–203

    Google Scholar 

  • Emini EA, Schleif WA, Armstrong ME, Silberklang M, Schultz LD, Lehman D, Maigetter RZ, Qualtiere LF, Pearson GR, Ellis RW (1988) Antigenic analysis of the Epstein-Barr virus major membrane antigen (gp350/220) expressed in yeast and mammalian cells: implications for the development of a subunit vaccine. Virology 166:387–393

    Article  PubMed  CAS  Google Scholar 

  • Emini E A, Schleif WA, Silberklang M, Lehman D, Ellis RW (1989) Vero cell- expressed Epstein-Barr virus (EBV) gp350/220 protects marmosets from EBV challenge. J Med Virol 27:120–123

    Article  PubMed  CAS  Google Scholar 

  • Epstein M, Achong B, Barr Y (1964) Virus particles in cultured lymphoblasts from Burkitt’s lymphoma. Lancet 1:702–703

    Article  PubMed  CAS  Google Scholar 

  • Epstein MA, Morgan AJ, Finerty S, Randle BJ, Kirkwood JK (1985) Protection of cottontop tamarins against Epstein-Barr virus-induced malignant lymphoma by a prototype subunit vaccine. Nature 318:287–289

    Article  PubMed  CAS  Google Scholar 

  • Finerty S, Tarlton J, Mackett M, Conway M, Arrand JR, Watkins PE, Morgan AJ (1992) Protective immunization against Epstein-Barr virus-induced disease in cottontop tamarins using the virus envelope glycoprotein gp340 produced from a bovine papillomavirus expression vector. J Gen Virol 73:449–453

    Article  PubMed  CAS  Google Scholar 

  • Fish KN, Britt W, Nelson JA (1996) A novel mechanism for persistence of human cytomegalovirus in macrophages. J Virol 70:1855–1862

    PubMed  CAS  Google Scholar 

  • Forrester A, Farrell H, Wilkinson G, Kaye J, Davis Poynter N, Minson T (1992) Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. J Virol 66:341–348

    PubMed  CAS  Google Scholar 

  • Fowler KB, Stagno S, Pass RF, Britt WJ, Boll TJ, Alford CA (1992) The outcome of congenital cytomegalovirus infection in relation to maternal antibodv status. N Engl J Med 326:663–667

    Article  PubMed  CAS  Google Scholar 

  • Frank AB (1938) Formalized herpes virus therapy and the neutralizing substance in herpes simplex. J Invest Dermatol 1:267–282

    Article  CAS  Google Scholar 

  • Fraser NW, Lawrence WC, Wroblewska Z, Gilden DH, Koprowski H (1981) Herpes simplex type 1 DNA in human brain tissue. Proc Natl Acad Sci USA 78:6461–6465

    Article  PubMed  CAS  Google Scholar 

  • Friedman AD, Furukawa T, Plotkin SA (1982) Detection of antibody to cytomegalovirus early antigen in vaccinated, normal volunteers and renal transplant candidates. J Infect Dis 146:255–259

    Article  PubMed  CAS  Google Scholar 

  • Fruh K, Ahn K, Djaballah H, Sempe P, van Endert PM, Tampe R, Peterson PA, Yang Y (1995) A viral inhibitor of peptide transporters for antigen presentation. Nature 375:415–418

    Article  PubMed  CAS  Google Scholar 

  • Fuller AO, Spear PG (1987) Anti-glycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surface. Proc Natl Acad Sci USA 84:5454–5458

    Article  PubMed  CAS  Google Scholar 

  • Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE (1992) Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group. J Infect Dis 166:1223–1227

    Article  PubMed  CAS  Google Scholar 

  • Gallant JE, Moore RD, Keruly J, Richman DD, Chaisson RE (1995) Lack of association between acyclovir use and survival in patients with advanced human immunodeficiency virus disease treated with zidovudine. Zidovudine Epidemiology Study Group. J Infect Dis 172:346–352

    Article  PubMed  CAS  Google Scholar 

  • Gehrz RC, Christianson WR, Linner KM, Groth KE, Balfour HH Jr (1980) Cytomegalovirus vaccine. Specific humoral and cellular immune responses in human volunteers. Arch Intern Med 140:936–939

    Article  PubMed  CAS  Google Scholar 

  • Gerdes JC, Smith DS (1983) Recurrence phenotypes and establishment of latency following rabbit keratitis produced by multiple herpes simplex virus strains. J Gen Virol 64:2441–2454

    Article  PubMed  Google Scholar 

  • Gilbert MJ, Riddell SR, Plachter B, Greenberg PD (1996) Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Nature 383:720–722

    Article  PubMed  CAS  Google Scholar 

  • Glazer JP, Friedman HM, Grossman RA, Starr SE, Barker CF, Perloff LJ, Huang ES, Plotkin SA (1979) Live cytomegalovirus vaccination of renal transplant candidates. A preliminary trial. Ann Intern Med 91:676–683

    PubMed  CAS  Google Scholar 

  • Gompels U, Minson A (1986) The properties and sequence of glycoprotein H of herpes simplex virus type 1. Virology 153:230–247

    Article  PubMed  CAS  Google Scholar 

  • Gonczol E, deTaisne C, Hirka G, Berencsi K, Lin WC, Paoletti E, Plotkin S (1991) High expression of human cytomegalovirus (HCMV)-gB protein in cells infected with a vaccinia-gB recombinant: the importance of the gB protein in HCMV immunity. Vaccine 9:631–637

    Article  PubMed  CAS  Google Scholar 

  • Gonczol E, Berensci K, Pincus S, Endresz V, Meric C, Paoletti E, Plotkin SA (1995) Preclinical evaluation of an ALVAC (canarypox)-human cytomegalovirus glycoprotein B vaccine candidate. Vaccine 13:1080–1085

    Article  PubMed  CAS  Google Scholar 

  • Gonzalez Armas JC, Morello CS, Cranmer LD, Spector DH (1996) DNA immunization confers protection against murine cytomegalovirus infection. J Virol 70:7921–7928

    PubMed  CAS  Google Scholar 

  • Goodpasture EW, Teague O (1923a) Surgical aspect of major neuralgia of trigeminal nerve: report of 20 cases of experimental production of herpetic lesions in organs and tissues of the rabbit. J Med Res 44:121–137

    CAS  Google Scholar 

  • Goodpasture EW, Teague O (1923b) Surgical aspect of major neuralgia of trigeminal nerve: report of 20 cases of transmission of the virus of herpestic febrilis along nerves in experimentally infected rabbits. J Med Res 44:139–184

    CAS  Google Scholar 

  • Griffiths PD (1993) Current management of cytomegalovirus disease. J Med Virol 1:106–111

    Article  PubMed  Google Scholar 

  • Gu SY, Huang TM, Ruan L, Miao YH, Lu H, Chu CM, Motz M, Wolf H (1995) First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen. Dev Biol Stand 84:171–177

    PubMed  CAS  Google Scholar 

  • Gudnadottir M, Helgadottir H, Bjarnason O, Jonsdottir K (1964) Virus isolated from the brain of a patient with multiple sclerosis. Exp Neurol 9:85–95

    Article  PubMed  CAS  Google Scholar 

  • Henle G, Henle W, Diehl V (1968) Relation of Burkitt’s tumour associated herpes-type virus to infectious mononucleosis. Proc Natl Acad Sci USA 59:94–101

    Article  PubMed  CAS  Google Scholar 

  • Herold BC, WuDunn D, Soltys N, Spear PG (1991) Glycoprotein C of herpes simplex virus type 1 plays a principal role in the adsorption of virus to cells and in infectivity. J Virol 65:1090–1098

    PubMed  CAS  Google Scholar 

  • Highlander SL, Cai WH, Person S, Levine M, Glorioso JC (1988) Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration. J Virol 62:1881–1888

    PubMed  CAS  Google Scholar 

  • Hill A, Jugovic P, York I, Russ G, Bennink J, Yewdell J, Ploegh H, Johnson D (1995) Herpes simplex virus turns off the TAP to evade host immunity. Nature 375:411–415

    Article  PubMed  CAS  Google Scholar 

  • Hoover DR, Saah AJ, Bacellar H, Phair J, Detels R, Anderson R, Kaslow RA (1993) Clinical manifestations of AIDS in the era of Pneumocystis prophylaxis. Multicenter AIDS Cohort Study. N Engl J Med 329:1922–1926

    Article  PubMed  CAS  Google Scholar 

  • Howard WT (1905) Further observation on the relation of lesions of the Gasserian and posterior root ganglia to herpes occurring in pneumonia and cerebrospinal meningitis. Am J Med Sci 130:1012–1019

    Article  Google Scholar 

  • Howe JG, Shu MD (1989) Epstein-Barr virus small RNA (EBER) genes: unique transcription units that combine RNA polymerase II and III promoter elements. Cell 57:825–834

    Article  PubMed  CAS  Google Scholar 

  • Hung SL, Peng C, Kostavasili I, Friedman HM, Lambris JD, Eisenberg RJ, Cohen GH (1994) The interaction of glycoprotein C of herpes simplex virus types 1 and 2 with the alternative complement pathway. Virology 203:299–312

    Article  PubMed  CAS  Google Scholar 

  • Javier RT, Stevens JG, Dissette VB, Wagner EK (1988) A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state. Virology 166:254–257

    Article  PubMed  CAS  Google Scholar 

  • Johnson DC, Frame MC, Ligas MW, Cross AM, Stow ND (1988) Herpes simplex virus immunoglobulin G Fc receptor activity depends on a complex of two viral glycoproteins, gE and gI. J Virol 62:1347–1354

    PubMed  CAS  Google Scholar 

  • Jones TR, Hanson LK, Sun L, Slater JS, Stenberg RM, Campbell AE (1995) Multiple independent loci within the human cytomegalovirus unique short region down- regulate expression of major histocompatibility complex class I heavy chains. J Virol 69:4830–4841

    PubMed  CAS  Google Scholar 

  • Jones TR, Wiertz EJ, Sun L, Fish KN, Nelson JA, Ploegh HL (1996) Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc Natl Acad Sci USA 93:11327–11333

    Article  PubMed  CAS  Google Scholar 

  • Kari B, Gehrz R (1992) A human cytomegalovirus glycoprotein complex designated gC-II is a major heparin-binding component of the envelope. J Virol 66:1761–1764

    PubMed  CAS  Google Scholar 

  • Kari B, Gehrz R (1993) Structure, composition and heparin binding properties of a human cytomegalovirus glycoprotein complex designated gC-II. J Gen Virol 74:255–264

    Article  PubMed  CAS  Google Scholar 

  • Keay S, Baldwin B (1991) Anti-idiotype antibodies that mimic gp86 of human cytomegalovirus inhibit viral fusion but not attachment. J Virol 65:5124–5128

    PubMed  CAS  Google Scholar 

  • Keay S, Merigan TC, Rasmussen L (1989) Identification of cell surface receptors for the 86-kilodalton glycoprotein of human cytomegalovirus. Proc Natl Acad Sci USA 86:10100–10103

    Article  PubMed  CAS  Google Scholar 

  • Kern AB, Schiff BL (1964) Vaccine therapy in recurrent herpes simplex. Arch Dermatol 89:844–845

    Article  PubMed  CAS  Google Scholar 

  • Khanna R, Slade RW, Poulsen L, Moss DJ, Burrows, SR, Nicholls J, Burrows JM (1997) Evolutionary dynamics of genetic variation in Epstein-Barr virus isolates of diverse geographical origins: evidence for immune pressure-independent genetic drift. J Virol 71:8340–8346

    PubMed  CAS  Google Scholar 

  • Kieff E (1996) Epstein-Barr virus and its replication. In: Fields BN (ed) Fields virology. Lippincott-Raven, New York, pp 2343–2396

    Google Scholar 

  • Klein RJ (1976) Pathogenetic mechansims of recurrent herpes simplex virus infections. Arch Virol 51:1–13

    Article  PubMed  CAS  Google Scholar 

  • Kriesel JD, Spruance SL, Daynes RA, Araneo BA (1996) Nucleic acid vaccine encoding gD2 protects mice from herpes simplex virus type 2 disease. J Infect Dis 173:536–541

    Article  PubMed  CAS  Google Scholar 

  • Kristensson K, Lycke E, Sjostrand J (1971) Spread of herpes simplex virus in peripheral nerves. Acta Neuropathol (Berl) 17:44–53

    Article  CAS  Google Scholar 

  • Kristensson K, Vahlne A, Persson LA, Lycke E (1978) Neural spread of herpes simplex virus types 1 and 2 in mice after corneal or subcutaneous (footpad) inoculation. J Neurol Sci 35:331–340

    Article  PubMed  CAS  Google Scholar 

  • Kristensson K, Svennerholm B, Persson L, Vahlne A, Lycke E (1979) Latent herpes simplex virus trigeminal ganglionic infection in mice and demyelination in the central nervous system. J Neurol Sci 43:253–263

    Article  PubMed  CAS  Google Scholar 

  • Kristensson K, Nennesmo L, Persson L, Lycke E (1982a) Neuron to neuron transmission of herpes simplex virus. Transport of virus from skin to brainstem nuclei. J Neurol Sci 54:149–156

    Article  CAS  Google Scholar 

  • Kristensson K, Svennerholm B, Vahlne A, Nilheden E, Persson L, Lycke E (1982b) Virus-induced demyelination in herpes simplex virus-infected mice. J Neurol Sci 53:205–216

    Article  CAS  Google Scholar 

  • Kristensson K, Lycke E, Roytta M, Svennerholm B, Vahlne A (1986) Neuritic transport of herpes simplex virus in rat sensory neurons in vitro. Effects of substances interacting with microtubular function and axonal flow [nocodazole, taxol and erythro-9-3-(2-hydroxynonyl)adenine]. J Gen Virol 67:2023–2028

    Article  PubMed  CAS  Google Scholar 

  • Kuhn JE, Kramer MD, Willenbacher W, Wieland U, Lorentzen EU, Braun RW (1990) Identification of herpes simplex virus type 1 glycoproteins interacting with the cell surface. J Virol 64:2491–2497

    PubMed  CAS  Google Scholar 

  • Kuklin N, Daheshia M, Karem K, Manickan E, Rouse BT (1997) Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization. J Virol 71:3138–3145

    PubMed  CAS  Google Scholar 

  • Langeland N, Holmsen H, Lillehaug JR, Haarr L (1987) Evidence that neomycin inhibits binding of herpes simplex virus type 1 to the cellular receptor. J Virol 61:3388–3393

    PubMed  CAS  Google Scholar 

  • Langeland N, Moore LJ, Holmsen H, Haarr L (1988) Interaction of polylysine with the cellular receptor for herpes simplex virus type 1. J Gen Virol 69:1137–1145

    Article  PubMed  CAS  Google Scholar 

  • Langeland N, Oyan AM, Marsden HS, Cross A, Glorioso JC, Moore LJ, Haarr L (1990) Localization on the herpes simplex virus type 1 genome of a region encoding proteins involved in adsorption to the cellular receptor. J Virol 64:1271–1277

    PubMed  CAS  Google Scholar 

  • Lee FK, Pereira L, Griffin C, Reid E, Nahmias A (1986) A novel glycoprotein for detection of herpes simplex virus type 1-specific antibodies. J Virol Methods 14:111–118

    Article  PubMed  CAS  Google Scholar 

  • Lewis ME, Leung WC, Jeffrey VM, Warren KG (1984) Detection of multiple strains of latent herpes simplex virus type 1 within individual human hosts. J Virol 52:300–305

    PubMed  CAS  Google Scholar 

  • Lipschutz B (1921) Untersuchungen über die Atiologie der Krankenheit der Herpesgruppe (herpes zoster, herpes genitalis, herpes febrilis). Arch Derm Syphilol 136:428–482

    Article  Google Scholar 

  • Liu YN, Curtsinger J, Donahue PR, Klaus A, Optiz G, Cooper J, Karr RW, Bach FH, Gehrz RC (1993) Molecular analysis of the immune response to human cytomegalovirus glycoprotein B. I. Mapping of HLA-restricted helper T cell epitopes on gp93. J Gen Virol 74:2207–2214

    Article  PubMed  CAS  Google Scholar 

  • Lowe RS, Keller PM, Keech BJ, Davison AJ, Whang Y, Morgan AJ, Kieff E, Ellis RW (1987) Varicella-zoster virus as a live vector for the expression of foreign genes. Proc Natl Acad Sci USA 84:3896–3900

    Article  PubMed  CAS  Google Scholar 

  • Lowhagen GB, Jansen E, Nordenfelt E, Lycke E (1990) Epidemiology of genital herpes infections in Sweden. Acta Derm Venereol (Stockh) 70:330–334

    CAS  Google Scholar 

  • Lundstrom M, Olofsson S, Jeansson S, Lycke E, Datema R, Mansson JE (1987) Host cell-induced differences in O-glycosylation of herpes simplex virus gC-1. I. Structures of nonsialylated HPA- and PNA-binding carbohydrates. Virology 161:385–394

    Article  PubMed  CAS  Google Scholar 

  • Lycke E, Kristensson K, Svennerholm B, Vahlne A, Ziegler R (1984) Uptake and transport of herpes simplex virus in neurites of rat dorsal root ganglia cells in culture. J Gen Virol 65:55–64

    Article  PubMed  Google Scholar 

  • Lycke E, Johansson M, Svennerholm B, Lindahl U (1991) Binding of herpes simplex virus to cellular heparan sulphate, an initial step in the adsorption process. J Gen Virol 72:1131–1137

    Article  PubMed  CAS  Google Scholar 

  • Mackett M, Conway MJ, Arrand JR, Haddad RS, Hutt Fletcher LM (1990) Characterization and expression of a glycoprotein encoded by the Epstein-Barr virus BamHI I fragment. J Virol 64:2545–2552

    PubMed  CAS  Google Scholar 

  • Madej M, Conway MJ, Morgan AJ, Sweet J, Wallace L, Qualtiere LF, Arrand JR, Mackett M (1992) Purification and characterization of Epstein-Barr virus gp340/220 produced by a bovine papillomavirus virus expression vector system. Vaccine 10:777–782

    Article  PubMed  CAS  Google Scholar 

  • Manickan E, Yu Z, Rouse RJ, Wire WS, Rouse BT (1995) Induction of protective immunity against herpes simplex virus with DNA encoding the immediate early protein ICP 27. Viral Immunol 8:53–61

    Article  PubMed  CAS  Google Scholar 

  • Manservigi R, Spear PG, Buchan A (1977) Cell fusion induced by herpes simplex virus is promoted and suppressed by different viral glycoproteins. Proc Natl Acad Sci USA 74:3913–3917

    Article  PubMed  CAS  Google Scholar 

  • Manzella JP, McConville JH, Valenti W, Menegus MA, Swierkosz EM, Arens M (1984) An outbreak of herpes simplex virus type I gingivostomatitis in a dental hygiene practice. JAMA 252:2019–2022

    Article  PubMed  CAS  Google Scholar 

  • Marshall GS (1997) Cytomegalovirus vaccines - two decades of progress. Herpes 4:20–24

    Google Scholar 

  • Marshall GS, Plotkin SA (1990) Progress toward developing a cytomegalovirus vaccine. Infect Dis Clin North Am 4:283–298

    PubMed  CAS  Google Scholar 

  • Marshall GS, Ricciardi RP, Rando RF, Puck J, Ge RW, Plotkin SA, Gonczol E (1990) An adenovirus recombinant that expresses the human cytomegalovirus major envelope glycoprotein and induces neutralizing antibodies. J Infect Dis 162:1177–1181

    Article  PubMed  CAS  Google Scholar 

  • Martin JR (1982) Spinal cord and optic nerve demyelination in experimental herpes simplex virus type 2 infection. J Neuropathol Exp Neurol 41:253–266

    Article  PubMed  CAS  Google Scholar 

  • Martin JR, Stoner GL (1984) The nervous system in genital herpes simplex virus type 2 infections in mice. Lethal panmyelitis or nonlethal demyelinative myelitis or meningitis. Lab Invest 51:556–566

    PubMed  CAS  Google Scholar 

  • Martin JR, Holt RK, Webster HD (1988) Herpes-simplex-related antigen in human demyelinative disease and encephalitis. Acta Neuropathol (Berl) 76:325–337

    Article  CAS  Google Scholar 

  • Mastrolorenzo A, Tiradritti L, Salimbeni L, Zuccati G (1995) Multicentre clinical trial with herpes simplex virus vaccine in recurrent herpes infection. Int J STD AIDS 6:431–435

    PubMed  CAS  Google Scholar 

  • Mauri DN, Ebner R, Montgomery RI, Kochel KD, Cheung TC, Yu GL, Ruben S, Murphy M, Eisenberg RJ, Cohen GH, Spear PG, Ware CF (1998) LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator. Immunity 8:21–30

    Article  PubMed  CAS  Google Scholar 

  • McCormick DP (1972) Herpes-simplex virus as a cause of Bell’s palsy. Lancet 1:937–939

    Article  PubMed  CAS  Google Scholar 

  • McDermott MR, Graham FL, Hanke T, Johnson DC (1989) Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing HSV glycoprotein B. Virology 169:244–247

    Article  PubMed  CAS  Google Scholar 

  • McLaughlin Taylor E, Pande H, Forman SJ, Tanamachi B, Li CR, Zaia JA, Greenberg PD, Riddell SR (1994) Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8+ virus-specific cytotoxic T lymphocytes. J Med Virol 43:103–110

    Article  PubMed  CAS  Google Scholar 

  • McLennan JL, Darby G (1980) Herpes simplex virus latency: the cellular location of virus in dorsal root ganglia and the fate of the infected cell following virus activation. J Gen Virol 51:233–243

    Article  PubMed  CAS  Google Scholar 

  • Meignier B, Longnecker R, Roizman B (1988) In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodents. J Infect Dis 158:602–614

    Article  PubMed  CAS  Google Scholar 

  • Meignier B, Martin B, Whitley RJ, Roizman B (1990) In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020. II. Studies in immunocompetent and immunosuppressed owl monkeys (Aotus trivirgatus). J Infect Dis 162:313–321

    Article  PubMed  CAS  Google Scholar 

  • Mocarski ES, Post LE, Roizman B (1980) Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions. Cell 22:243–255

    Article  PubMed  CAS  Google Scholar 

  • Mocarski ES Jr (1996) Cytomegaloviruses and their replication. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, New York, pp 2447–2492

    Google Scholar 

  • Montgomery RI, Warner MS, Lum BJ, Spear PG (1996) Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell 87:427–436

    Article  PubMed  CAS  Google Scholar 

  • Morgan C, Rose HM, Mednis B (1968) Electron microscopy of herpes simplex virus. I. Entry. J Virol 2:507–516

    PubMed  CAS  Google Scholar 

  • Morgan AJ, Mackett M, Finerty S, Arrand JR, Scullion FT, Epstein MA (1988) Recombinant vaccinia virus expressing Epstein-Barr virus glycoprotein gp340 protects cottontop tamarins against EB virus-induced malignant lymphomas. J Med Virol 25 189–195

    Article  PubMed  CAS  Google Scholar 

  • Morgan JA (1992) Epstein-Barr virus vaccines. Vaccine 10:563–571

    Article  PubMed  CAS  Google Scholar 

  • Morrison LA, Knipe DM (1994) Immunization with replication-defective mutants of herpes simplex virus type 1: sites of immune intervention in pathogenesis of challenge virus infection. J Virol 68:689–696

    PubMed  CAS  Google Scholar 

  • Moss DJ, Schmidt C, Elliott S, Suhrbier A, Burrows S, Khanna R. (1996) Strategies involved in developing an effective vaccine for EBV-associated diseases. Adv Cancer Res 69:213–245

    Article  PubMed  CAS  Google Scholar 

  • Murphy FA (1996) Virus taxonomy. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, New York, pp 15–58

    Google Scholar 

  • Nahmias AJ, Dowdle WR (1968) Antigenic and biological differences in herpesvirus hominis. Prog Med Virol 10:110–159

    PubMed  CAS  Google Scholar 

  • Navarro D, Paz P, Tugizov S, Topp K, La Vail J, Pereira L (1993) Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells. Virology 197:143–158

    Article  PubMed  CAS  Google Scholar 

  • Nicholls SM, Blyth WA (1989) Quantification of herpes simplex virus infection in cervical ganglia of mice. J Gen Virol 70:1779–1788

    Article  PubMed  Google Scholar 

  • Nilheden E, Jeansson S, Vahlne A (1985) Herpes simplex virus latency in a hyperresistant clone of mouse neuroblastoma (C1300) cells. Arch Virol 83:319–325

    Article  PubMed  CAS  Google Scholar 

  • Olding LB, Kingsbury DT, Oldstone MB (1976) Pathogenesis of cytomegalovirus infection. Distribution of viral products, immune complexes and autoimmunity during latent murine infection. J Gen Virol 33:267–280

    Article  PubMed  CAS  Google Scholar 

  • Olofsson S, Lundstrom M, Marsden H, Jeansson S, Vahlne A (1986) Characterization of a herpes simplex virus type 2-specified glycoprotein with affinity for N-acetylgalactosamine-specific lectins and its identification as g92 K or gG. J Gen Virol 67:737–744

    Article  PubMed  CAS  Google Scholar 

  • Pande H, Campo K, Tanamachi B, Forman SJ, Zaia JA (1995) Direct DNA immunization of mice with plasmid DNA encoding the tegument protein pp65 (ppUL83) of human cytomegalovirus induces high levels of circulating antibody to the encoded protein. Scand J Infect Dis [Suppl] 99:117–120

    CAS  Google Scholar 

  • Pereira L (1994) Function of glycoprotein B homologues of the family herpesviridae. Infect Agents Dis 3:9–28

    PubMed  CAS  Google Scholar 

  • Plotkin SA, Huang ES (1985) Cytomegalovirus vaccine virus (Towne strain) does not induce latency. J Infect Dis 152:395–397

    Article  PubMed  CAS  Google Scholar 

  • Plotkin SA, Huygelen C (1976) Cytomegalovirus vaccine prepared in WI-38. Dev Biol Stand 37:301–305

    PubMed  CAS  Google Scholar 

  • Plotkin SA, Farquhar J, Horberger E (1976) Clinical trials of immunization with the Towne 125 strain of human cytomegalovirus. J Infect Dis 134:470–475

    Article  PubMed  CAS  Google Scholar 

  • Plotkin SA, Smiley ML, Friedman HM, Starr SE, Fleisher GR, Wlodaver C, Dafoe DC, Friedman AD, Grossman RA, Barker CF (1984) Prevention of cytomegalovirus disease by Towne strain live attenuated vaccine. Birth Defects 20:271–287

    PubMed  CAS  Google Scholar 

  • Plotkin SA, Starr SE, Friedman HM, Gonczol E, Brayman K (1990) Vaccines for the prevention of human cytomegalovirus infection. Rev Infect Dis 12 [Suppl 7]:S827–S838

    Article  PubMed  Google Scholar 

  • Plotkin SA, Starr SE, Friedman HM, Brayman K, Harris S, Jackson S, Tustin NB, Grossman R, Dafoe D, Barker C (1991) Effect of Towne live virus vaccine on cytomegalovirus disease after renal transplant. A controlled trial. Ann Intern Med 114:525–531

    PubMed  CAS  Google Scholar 

  • Plotkin SA, Higgins R, Kurtz JB, Morris PJ, Campbell DA Jr, Shope TC, Spector SA, Dankner WM (1994) Multicenter trial of Towne strain attenuated virus vaccine in seronegative renal transplant recipients. Transplantation 58:1176–1178

    PubMed  CAS  Google Scholar 

  • Post LE, Roizman B (1981) A generalized technique for deletion of specific genes in large genomes: alpha gene 22 of herpes simplex virus 1 is not essential for growth. Cell 25:227–232

    Article  PubMed  CAS  Google Scholar 

  • Quinnan GV Jr, Delery M, Rook AH, Frederick WR, Epstein JS, Manischewitz JF, Jackson L, Ramsey KM, Mittal K, Plotkin SA et al (1984) Comparative virulence and immunogenicity of the Towne strain and a nonattenuated strain of cytomegalovirus. Ann Intern Med 101:478–483

    PubMed  Google Scholar 

  • Ragot T, Finerty S, Watkins PE, Perricaudet M, Morgan AJ (1993) Replication- defective recombinant adenovirus expressing the Epstein-Barr virus (EBV) envelope glycoprotein gp340/220 induces protective immunity against EBV-induced lymphomas in the cottontop tamarin. J Gen Virol 74:501–507

    Article  PubMed  CAS  Google Scholar 

  • Rasmussen L, Resta S, Merigan T (1991) Human cytomegalovirus glycoprotein-receptor interactions. Transplant Proc 23:60–63

    PubMed  CAS  Google Scholar 

  • Reeves WC, Corey L, Adams HG, Vontver LA, Holmes KK (1981) Risk of recurrence after first episodes of genital herpes. Relation to HSV type and antibody response. N Engl J Med 305:315–319

    Article  PubMed  CAS  Google Scholar 

  • Ribbert H (1904) Über protozoanartige Zellen in der Niere eines syphilitischen Neugeboren und in der Parotis von Kindern. Zentralbl Allg Path Path Anat 15:945–948

    Google Scholar 

  • Rickinson AB, Kieff E (1996) Epstein-Barr Virus. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, New York, pp 2397–2446

    Google Scholar 

  • Roizman B, Sears AE (1996) Herpes simplex viruses and their replication. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, New York, pp 2231–2295

    Google Scholar 

  • Rosenhall U, Edstrom S, Hanner P, Badr G, Vahlne A (1983) Auditory brain stem response abnormalities in patients with Bell’s palsy. Otolaryngol Head Neck Surg 91:412–416

    PubMed  CAS  Google Scholar 

  • Rosenthal SL, Stanberry LR, Biro FM, Slaoui M, Francotte M, Koutsoukos M, Hayes M, Bernstein DI. (1997) Seroprevalence of herpes simplex virus types 1 and 2 and cytomegalovirus in adolescents. Clin Infect Dis 24:135–139

    Article  PubMed  CAS  Google Scholar 

  • Rowe WP, Hartley JW, Waterman S, Turner HC, Huebner RJ (1956) Cytopathogenic agents resembling human salivary gland virus recovered from tissue cultures of human adenoids. Proc Soc Exp Biol Med 92:418–424

    PubMed  CAS  Google Scholar 

  • Rowe M, Rowe DT, Gregory CD, Young LS, Farrell PJ, Rupani H, Rickinson AB (1987) Differences in B cell growth phenotype reflect novel patterns of Epstein- Barr virus latent gene expression in Burkitt’s lymphoma cells. EMBO J 6:2743–2751

    PubMed  CAS  Google Scholar 

  • Rustigan R, Smulow JB, Tye M, Gibson WA, Shindell E (1966) Studies on latent infection of skin and oral mucosa in individuals with recurrent herpes simplex. J Invest Dermatol 47:218–221

    Google Scholar 

  • Rymo L (1979) Identification of transcribed regions of Epstein-Barr virus DNA in Burkitt lymphoma-derived cells. J Virol 32:8–18

    PubMed  CAS  Google Scholar 

  • Sedmak DD, Guglielmo AM, Knight DA, Birmingham DJ, Huang EH, Waldman WJ (1994) Cytomegalovirus inhibits major histocompatibility class II expression on infected endothelial cells. Am J Pathol 144:683–692

    PubMed  CAS  Google Scholar 

  • Sjoblom I, Lundstrom M, Sjogren Jansson E, Glorioso JC, Jeansson S, Olofsson S (1987) Demonstration and mapping of highly carbohydrate-dependent epitopes in the herpes simplex virus type 1-specified glycoprotein C. J Gen Virol 68:545–554

    Article  PubMed  Google Scholar 

  • Skinner GR, Turyk ME, Benson CA, Wilbanks GD, Heseltine P, Galpin J, Kaufman R, Goldberg L, Hartley CE, Buchan A (1997) The efficacy and safety of Skinner herpes simplex vaccine towards modulation of herpes genitalis; report of a prospective double-blind placebo-controlled trial. Med Microbiol Immunol (Berl) 186:31–36

    Article  CAS  Google Scholar 

  • Skoldenberg B, Jeansson S, Wolontis S (1973) Herpes simplex virus type 2 in acute aseptic meningitis. BMJ 2:611

    Article  PubMed  CAS  Google Scholar 

  • Smith MG (1956) Propagation in tissue cultures of a cytopathogenic virus from human salivary gland virus disease. Proc Soc Exp Biol Med 92:424–430

    PubMed  CAS  Google Scholar 

  • Söderberg C (1995) Thesis. Karolinska institutet, Stockholm

    Google Scholar 

  • Söderberg Naucler C, Fish KN, Nelson JA (1997) Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors. Cell 91:119–126

    Article  PubMed  Google Scholar 

  • Soffer D, Martin JR (1988) Remyelination of central nervous system lesions in experimental genital herpes simplex virus infection. J Neurol Sci 86:83–95

    Article  PubMed  CAS  Google Scholar 

  • Spear PG (1985) Glycoproteins specified by herpes simplex virus. In: Roizman B (ed) The herpesviruses. Plenum, New York, pp 315–356

    Chapter  Google Scholar 

  • Stagno S, Reynolds DW, Huang ES, Thames SD, Smith RJ, Alford CA (1977) Congenital cytomegalovirus infection. N Engl J Med 296:1254–1258

    Article  PubMed  CAS  Google Scholar 

  • Stagno S, Pass RF, Cloud G, Britt WJ, Henderson RE, Walton PD, Veren DA, Page F, Alford CA (1986) Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus, and clinical outcome. JAMA 256:1904–1908

    Article  PubMed  CAS  Google Scholar 

  • Starr SE, Glazer JP, Friedman HM, Farquhar JD, Plotkin SA (1981) Specific cellular and humoral immunity after immunization with live Towne strain cytomegalovirus vaccine. J Infect Dis 143:585–589

    Article  PubMed  CAS  Google Scholar 

  • Stevens JG (1975) Herpes simplex viral latency - a review. IARC Sci Publ 11 (2): 67–72

    PubMed  Google Scholar 

  • Stevens JG, Newburn AB, Cook ML (1972) Latent herpes simplex virus from trigeminal ganglia of rabbits with recurrent eye infection. Nat New Biol 235:216–217

    PubMed  CAS  Google Scholar 

  • Straus SE, Wald A, Kost RG, McKenzie R, Langenberg AG, Hohman P, Lekstrom J, Cox E, Nakamura M, Sekulovich R, Izu A, Dekker C, Corey L (1997) Immunotherapy of recurrent genital herpes with recombinant herpes simplex virus type 2 glycoproteins D and B: results of a placebo-controlled vaccine trial. J Infect Dis 176:1129–1134

    Article  PubMed  CAS  Google Scholar 

  • Sturn B, Schneweis KE (1978) Protective effect of an oral infection with herpes simplex virus type 1 against subsequent genital infection with herpes simplex virus type 2. Med Microbiol Immunol (Berl) 165:119–127

    Article  CAS  Google Scholar 

  • Svennerholm B, Vahlne A, Lycke E (1981) Persistent reactivable latent herpes simplex virus infection in trigeminal ganglia of mice treated with antiviral drugs. Arch Virol 69:43–48

    Article  PubMed  CAS  Google Scholar 

  • Svennerholm B, Olofsson S, Lunden R, Vahlne A, Lycke E (1982) Adsorption and penetration of enveloped herpes simplex virus particles modified by tunicamycin or 2-deoxy-D-glucose. J Gen Virol 63:343–349

    Article  PubMed  CAS  Google Scholar 

  • Svennerholm B, Olofsson S, Jeansson S, Vahlne A, Lycke E (1984) Herpes simplex virus type-selective enzyme-linked immunosorbent assay with Helix pomatia lectin-purified antigens. J Clin Microbiol 19:235–239

    PubMed  CAS  Google Scholar 

  • Svennerholm B, Jeansson S, Vahlne A, Lycke E (1991) Involvement of glycoprotein C (gC) in adsorption of herpes simplex virus type 1 (HSV-1) to the cell. Arch Virol 120:273–279

    Article  PubMed  CAS  Google Scholar 

  • Taylor HP, Cooper NR (1990) The human cytomegalovirus receptor on fibroblasts is a 30-kilodalton membrane protein. J Virol 64:2484–2490

    PubMed  CAS  Google Scholar 

  • Thomander L, Aldskogius H, Vahlne A, Kristensson K, Thomas E (1988) Invasion of cranial nerves and brain stem by herpes simplex virus inoculated into the mouse tongue. Ann Otol Rhinol Laryngol 97:554–558

    PubMed  CAS  Google Scholar 

  • Thomas E, Lycke E, Vahlne A (1985) Retrieval of latent herpes simplex virus type 1 genetic information from murine trigeminal ganglia by superinfection with heterotypic virus in vivo. J Gen Virol 66:1763–1770

    Article  PubMed  Google Scholar 

  • Tomazin R, Hill AB, Jugovic P, York I, van Endert P, Ploegh HL, Andrews DW, Johnson DC (1996) Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP. EMBO J 15:3256–3266

    PubMed  CAS  Google Scholar 

  • Trybala E, Bergstrom T, Svennerholm B, Jeansson S, Glorioso JC, Olofsson S (1994) Localization of a functional site on herpes simplex virus type 1 glycoprotein C involved in binding to cell surface heparan sulphate. J Gen Virol 75:743–752

    Article  PubMed  CAS  Google Scholar 

  • Tullo AB, Easty DL, Hill TJ, Blyth WA (1982) Ocular herpes simplex and the establishment of latent infection. Trans Ophthalmol Soc UK 102:15–18

    PubMed  Google Scholar 

  • Vahlne A, Nystrom B, Sandberg M, Hamberger A, Lycke E (1978) Attachment of herpes simplex virus to neurons and glial cells. J Gen Virol 40:359–371

    Article  PubMed  CAS  Google Scholar 

  • Vahlne A, Svennerholm B, Lycke E (1979) Evidence for herpes simplex virus type-selective receptors on cellular plasma membranes. J Gen Virol 44:217–225

    Article  PubMed  CAS  Google Scholar 

  • Vahlne A, Svennerholm B, Sandberg M, Hamberger A, Lycke E (1980) Differences in attachment between herpes simplex type 1 and type 2 viruses to neurons and glial cells. Infect Immun 28:675–680

    PubMed  CAS  Google Scholar 

  • Vahlne A, Edstrom S, Arstila P, Beran M, Ejnell H, Nylen O, Lycke E (1981a) Bell’s palsy and herpes simplex virus. Arch Otolaryngol 107:79–81

    CAS  Google Scholar 

  • Vahlne A, Nilheden E, Svennerholm B (1981b) Multiplicity activation of herpes simplex virus in mouse neuroblastoma (CI 300) cells. Arch Virol 70:345–356

    Article  CAS  Google Scholar 

  • Vahlne A, Edstrom S, Hanner P, Andersen O, Svennerholm B, Lycke E (1985) Possible association of herpes simplex virus infection with demyelinating disease. Scand J Infect Dis Suppl 47:16–21

    PubMed  CAS  Google Scholar 

  • von Glahn WC, Pappenheimer AM (1925) Intranuclear inclusions in visceral disease. Am J Pathol 1:445–465

    Google Scholar 

  • Wang JB, Adler SP, Hempfling S, Burke RL, Duliege AM, Starr SE, Plotkin SA (1996) Mucosal antibodies to human cytomegalovirus glycoprotein B occur following both natural infection and immunization with human cytomegalovirus vaccines. J Infect Dis 174:387–392

    Article  PubMed  CAS  Google Scholar 

  • Warren AP, Ducroq DH, Lehner PJ, Borysiewicz LK (1994) Human cytomegalovirus- infected cells have unstable assembly of major histocompatibility complex class I complexes and are resistant to lysis by cytotoxic T lymphocytes. J Virol 68:2822–2829

    PubMed  CAS  Google Scholar 

  • Wechsler SL, Nesburn AB, Watson R, Slanina SM, Ghiasi H (1988) Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related RNAs containing open reading frames. J Virol 62:4051–4058

    PubMed  CAS  Google Scholar 

  • Weitgasser H (1977) Controlled clinical study of the herpes antigens (Lupidon H, Lupidon G). Z Hautkr 52:625–628

    PubMed  CAS  Google Scholar 

  • Weller TTH, Macaulay JC, Craig JM, Wirth P (1957) Isolation of intranuclear inclusion producing agents from infants with illnesses resemling cytomegalic inclusion disease. Proc Soc Exp Biol Med 94:4–12

    PubMed  Google Scholar 

  • Weller TTH, Hanshaw JB, Scott DE (1960) Cytopathogenic agents resembling human salivary gland virus recovered from tissue cultures of human adenoids. Virologv 12:130–132

    Article  CAS  Google Scholar 

  • Whitley RJ (1996) Herpes simplex virus. In: Fields BN, Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, New York, pp 2297–2342

    Google Scholar 

  • Whitley RJ (1997) Herpes simplex vaccines. In: Levine MM, Woodrow GC, Kaper JB, Cobon GS (eds) New generation vaccines. Dekker, New York, pp 727–747

    Google Scholar 

  • Whitley RJ, Soong SJ, Linneman C Jr, Liu C, Pazin G, Alford CA (1982) Herpes simplex encephalitis. Clinical assessment. JAMA 247:317–320

    Article  PubMed  CAS  Google Scholar 

  • Wiertz EJ, Jones TR, Sun L, Bogyo M, Geuze HJ, Ploegh HL (1996a) The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84:769–779

    Article  CAS  Google Scholar 

  • Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, Jones TR, Rapoport TA, Ploegh HL (1996b) Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 384:432–438

    Article  CAS  Google Scholar 

  • Wiertz EJ, Mukherjee S, Ploegh HL (1997) Viruses use stealth technology to escape from the host immune system. Mol Med Today 3:116–123

    Article  PubMed  CAS  Google Scholar 

  • Wilcox CL, Johnson EM Jr (1987) Nerve growth factor deprivation results in the reactivation of latent herpes simplex virus in vitro. J Virol 61:2311–2315

    PubMed  CAS  Google Scholar 

  • Wu CT, Levine M, Homa F, Highlander SL, Glorioso JC (1990) Characterization of the antigenic structure of herpes simplex virus type 1 glycoprotein C through DNA sequence analysis of monoclonal antibody-resistant mutants. J Virol 64:856–863

    PubMed  CAS  Google Scholar 

  • WuDunn D, Spear PG (1989) Initial interaction of herpes simplex virus with cells is binding to heparan sulfate. J Virol 63:52–58

    PubMed  CAS  Google Scholar 

  • York IA, Roop C, Andrews DW, Riddell SR, Graham FL, Johnson DC (1994) A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes. Cell 77:525–535

    Article  PubMed  CAS  Google Scholar 

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  1. A. Vahlne
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  2. T. Bergström
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  1. The Wenner-Gren Institute Department of Immunology The Arrhenius Laboratories F5, Stockholm University, S-106 91, Stockholm, Sweden

    Peter Perlmann (Professor) (Professor)

  2. MTC, Karolinska Institute, S-171 77, Stockholm, Sweden

    Hans Wigzell (Professor) (Professor)

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Vahlne, A., Bergström, T., Svennerholm, B. (1999). Herpes. In: Perlmann, P., Wigzell, H. (eds) Vaccines. Handbook of Experimental Pharmacology, vol 133. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59955-2_7

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