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Chemoprevention of Human Cancer:A Reasonable Strategy?

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Chemoprevention of Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 151))

Abstract

The field of chemoprevention of cancer in humans is at a teenage level of maturity. There is anticipation and energy, and some promising results have come in, but it’s unclear whether the entire enterprise is worth the effort. Reflecting on the status of the organism and where we are in its developmental history is therefore an important exercise at this time. Empirical and philosophical perspectives are offered for several key questions: Why prevent Cancer? What is the preclinical evidence that chemoprevention of cancer in humans should work? What is the clinical evidence that chemoprevention agents work? What is the clinical evidence that chemoprevention agent don’t work? What is the status of ongoing randomized phase III/IV chemoprevention trials? The answers to each of these questions provide a part of the scaffold for a logical platform for the launching of the chemoprevention imperative as an integral part of our approach to the overall management of human cancer.

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Author information

Authors and Affiliations

  1. Chao Family Comprehensive Cancer Center, University of California, (Irvine), Orange, CA, 92668, USA

    Frank L. Meyskens Jr.

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  1. Frank L. Meyskens Jr.
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Editor information

Editors and Affiliations

  1. Center for Tumordetection and Prevention, Rorschacherstrasse 150, CH-9006, St. Gallen, Switzerland

    Hans-Jörg Senn

  2. European Institute of Oncology, Via Ripamonti, I-20141, Milan, Italy

    Alberto Costa M.D.

  3. Robert H. Lurie Cancer Center Breast Cancer Research Program, Olson Pavilion, Northwest-University Medical School, 503 E. Chicago Ave., 60611, Chicago, IL, USA

    V. Craig Jordan

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© 1999 Springer-Verlag Berlin · Heidelberg

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Meyskens, F.L. (1999). Chemoprevention of Human Cancer:A Reasonable Strategy?. In: Senn, HJ., Costa, A., Jordan, V.C. (eds) Chemoprevention of Cancer. Recent Results in Cancer Research, vol 151. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59945-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-59945-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64192-3

  • Online ISBN: 978-3-642-59945-3

  • eBook Packages: Springer Book Archive

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