Abstract
Racial variability in skin function is an area in which data are often conflicting. The understanding and quantifying of racial differences in skin function are of importance for skin care and the prevention and treatment of skin diseases. A key feature that characterizes race is skin color: is deeply pigmented skin (black or brown) different than fair skin in terms of responses to chemical and environmental insults? Is skin care the same? Is there a different risk among racial groups to develop a skin disease after exposure to the same insults? The issue is difficult to define and the interpretation of pathophysiologic phenomena should consider not only anatomical and functional characteristics of ethnic groups, but also socioeconomic, hygienic and nutritional factors. Indeed, even though it is well established that all humans belong to the same species, many physical differences exist among human populations. These differences, appeared during the latest stages of evolution, could be due both to genetic and environmental factors [1]. This paper reviews and discusses recent findings as relates to claim support.
Modified with permission from [1]
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References
Shriver MD (1997) Ethnic variation as a key to the biology of human disease. Ann Intern Med 127:401–403
Freeman RG, Cockerell EG, Armstrong J et al. (1962) Sunlight as a factor influencing the thickness of epidermis. J Invest Dermatol 39:295–297
Thomson ML (1955) Relative efficiency of pigment and horny layer thickness in protecting the skin of European and Africans against solar ultraviolet radiation. J Physiol (Lond) 127:236
Weigand DA, Haygood C, Gaylor JR (1974) Cell layers and density of Negro and Caucasians stratum corneum. J Invest Dermatol 62:563–565
Rienertson RP, Wheatley VR (1959) Studies on the chemical composition of human epidermal lipids. J Invest Dermatol 32:49–51
Johnson LC, Corah NL (1963) Racial differences in skin resistance. Science 139:766–769
Corcuff P, Lotte C, Rougier A, Maibach H (1991) Racial differences in corneocytes. Acta Dermatol Venereol (Stockh) 71:146–148
Sugino K, Imokawa G, Maibach H (1993) Ethnic difference of stratum corneum lipid in relation to stratum corneum function. J Invest Dermatol 100:597
Kompaore F, Marty JP, Dupont Ch (1993) In vivo evaluation of the stratum corneum barrier function in Blacks, Caucasians and Asians with two noninvasive methods. Skin Pharmacol 6:200–207
Reed JT, Ghadially R, Elias PM (1994) Effect of race, gender and skin type on epidermal permeability barrier function. J Invest Dermatol 102:537
Anderson R, Parrish J (1981) The optics of human skin. J Invest Dermatol 77:13–17
Pathak MA, Fitzpatrick TB (1974) The role of natural photoprotective agents in human skin. In: Fitzpatrick TB, Pathak MA, Harber RC et al. (eds) Sunlight and man. University of Tokyo Press, Tokyo, pp 725–750
Everett MA, Yeagers E, Sayre RM et al. (1966) Penetration of epidermis by ultraviolet rays. Photochem Photobiol 5:533
Kaidbey KH, Poh Agin P, Sayre RM et al. (1979) Photoprotection by melanin-a comparison of black and Caucasian skin. Am Acad Dermatol 1:249
Szabo G, Gerald AB, Pathak MA (1969) Racial differences in the fate of melanosomes in human epidermis. Nature 222:1081
Hausser KW, Vahle W (1969) Sunburn and suntanning. In: Urbach F (ed) The biologic effect of ultraviolet radiation. Pergamon, London, pp 13–21
Olson RL, Gaylor J, Everett MA (1973) Skin color, melanin and erythema. Arch Dermatol 108:541–544
Stoughton RB (1969) Bioassay methods for measuring percutaneous absorption. In: Montagna W, Stoughton RB, Van Scott EJ (eds) Pharmacology of the skin. Appleton-Century-Crofts, New York, p 542
Bronaugh RL, Stewart FR, Simon M (1986) Methods for in vitro percutaneous absorption studies VII: use of excised human skin. J Pharm Sci 75:1094
Berardesca E, Maibach HI (1989) Physical antrolopgy and skin: a model for exploring skin function. In: Maibach HI, Lowe N (eds) Models in dermatology 4. Karger, Basel, pp 202–208
Wickema-Sinha WJ, Shaw SR, Weber OJ (1978) Percutaneous absorption and excretion ot tritiumlabelled diflorasone diacetate, a new topical corticosteroid in the rat, monkey and man. J Invest Dermatol 71:372–377
Hymes JA, Spraker MK (1986) Racial differences in the effectiveness of a topically applied mixture of local anesthetics. Reg Anesth 11:11–13
Wedig JH, Maibach HI (1981) Percutaneous penetration of dipyrithione in man: effect of skin color (race). Am Acad Dermatol 5:433–438
Guy RH, Tur E, Bierke S et al. (1985)Are there age and racial differences to mrthyl nicotinate-induced vasodilatation in human skin? J Am Acad Dermatol 12:1001
Berardesca E, Maibach HI (1988) Contact dermatitis in blacks. Dermatol Clin 6:363–368
Lin S, Ho H, Chien YW (1993) Development of a new nicotine transdermal delivery system: in vitro kinetics studies and clinical pharmacokinetic evaluations in two ethnic groups. J Contr Rel 26:175–193
Berardesca E,de Rigal J,Leveque JL, Maibach HI (1991) In vivo biophysical characterization of skin physiological differences in races. Dermatologica 182:89–93
Berardesca E, Maibach HI (1988) Racial differences in sodium lauryl sulphate induced cutaneous irritation: Black and white. Contact Dermatitis 18:65–70
Berardesca E, Maibach HI (1988) Sodium lauryl sulphate induced cutaneous irritation. Comparison of white and Hispanic subjects. Contact Dermatitis 19:136–140
Rietschel RL (1978) A method to evaluate skin moisturizers in vivo. J Invest Dermatol 70:152–155
Wilson D, Berardesca E, Maibach HI (1988) In vitro transepidermal water loss: differences between black and white human skin. Br J Dermatol 119:647–652
Marshall EK, Lynch V, Smith HV (1919) Variation in susceptibility of the skin to dichloroethylsulfide. J Pharmacol Exp Ther 12:291–301
Edgewood Arsenal Technical Report (1970) The cutaneous irritant reaction to agent O-chlorobenzylidene malonitrile (CS). Quantitation and racial influence in human subjects. Edgewood Arsenal Technical Report 4332, February 1970
Weigand DA, Gaylor JR (1974) Irritant reaction in Negro and Caucasian skin. South Med J 67:548–551
Frosh P, Kligman AM (1981) A method for appraising the stinging capacity of topically applied substances. J Soc Cosmet Chem 28:197
Grove GL, Soschin DM, Kligman AM (1984) Adverse subjective reactions to topical agents. In: Drill VA, Lazar P (eds) Cutaneous toxicology. Raven, New York
Kenney J (1970) Dermatoses seen in American Negroes. Int J Dermatol 9:110–113
Marshall J, Heyl T (1963) Skin diseases in the Western Cape Province. S Afr Med J 37:1308
Dogliotti M (1970) Skin disorders in the Bantu: a survey of 2000 cases from Baragwanath Hospital. S Afr Med J 44:670
Scott F (1972) Skin diseases in the South African Bantu. In: Marshall J (ed) Essays on tropical dermatology. Excerpta Medica, Amsterdam
Kligman AM, Epstein W (1975) Updating the maximization test for identifying contact allergens. Contact Dermatitis 1:231
Fisher AA (1977) Contact dermatitis in black patients. Cutis 20:303–320
Olumide YM (1985) Contact dermatitis in Nigeria. Contact Dermatitis 12:241–246
Fregert S, Hjorth N, Magnusson B et al. (1969) Epidemiology of contact dermatitis. Trans St John’s Hosp Dermatol Soc 55:17
Fisher AA (1976) Vitiligo due to contactants. Cutis 17:431–437
Kahn G (1970) Depigmentation caused by phenolic detergent germicides. Arch Dermatol 102:177–187
Verhagen AR (1974) Pomade acne in black patients. Arch Dermatol 110:465
Plewig G, Fulton JE, Kligman AM (1970) Pomade acne. Arch Dermatol 101:580
Kaidbey KH, Kligman AM (1974) A human model for coal tar acne. Arch Dermatol 109:212–215
Berardesca E, Maibach HI (1989) Cutaneous reactive hyperaemia: racial differences induced by corticoid application. Br J Dermatol 120:787–794
Andersen KE, Maibach HI (1979) Black and white human skin differences. I Am Acad Dermatol 1:276–282
Berardesca E, Maibach H (1996) Racial differences in skin pathophysiology. J Am Acad Dermatol 34:667–672
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Berardesca, E., Maibach, H.I. (1999). Racial Differences in Skin Function: Related to Claim Support. In: Elsner, P., Maibach, H.I., Merk, H.F. (eds) Cosmetics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59869-2_15
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DOI: https://doi.org/10.1007/978-3-642-59869-2_15
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