Skip to main content
SpringerLink
Log in

Genetic and Environmental Influence on Development of the Filamentous Fungus Neurospora crassa

  • Chapter
Development

Abstract

Fungi are eukaryotic, heterotrophic organisms with an absorptive mode of nutrition. Most fungi grow in yeast-like or filamentous forms which are characteristically multicellular and multinucleate. The fungal cell is, in most cases, protected by a rigid polysaccharide wall. Recently, in recognition of the unique nutritional and morphological attributes of fungi, as expressed in the immensely diverse habitats and niches various fungi accommodate, taxonomists have elevated their taxonomic ranking to a separate kingdom — The Fifth Kingdom, on equal footing with plants and animals. The genetics of naturally occurring inter- and intraspecific fungal diversity and the speciation in fungi have been reviewed by Perkins (1991).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bennet JW, Lasure LL (1991) More gene manipulations in fungi. Academic Press, San Diego

    Google Scholar 

  2. Botstein D, Chervitz SA, Cherry JM (1997) Yeast as a model organism. Science 277:1259–1260

    Article  PubMed  CAS  Google Scholar 

  3. Carlile MJ (1994) The success of the hypha and mycelium. In: Gow NAR, Gadd GM (eds) The growing fungus. Chapman and Hall, London, pp 3–20

    Chapter  Google Scholar 

  4. Metzenberg RL (1979) Implications of some genetic control mechanisms in Neurospora. Microbiol Rev 43:361–383

    PubMed  CAS  Google Scholar 

  5. Perkins DD (1991) In praise of diversity. In: Bennet JW, Lasure LL (eds) More gene manipulations in fungi. Academic Press, San Diego, pp 3–26

    Google Scholar 

  6. Beadle GW, Tatum, EL (1941) Genetic control of chemical reactions in Neurospora. Proc Natl Acad Sci USA 27:499–506

    Article  PubMed  CAS  Google Scholar 

  7. Perkins DD (1992) Neurospora: the organism behind the molecular revolution. Genetics 130:687–701

    PubMed  CAS  Google Scholar 

  8. Davis RH, de Serres FJ (1970) Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol 27A:79–143

    Article  Google Scholar 

  9. Perkins DD, Radford A, Newmeyer D, Bjorkman M (1982) Chromosomal loci of Neurospora crassa. Microbiol Rev 46:426–570

    PubMed  CAS  Google Scholar 

  10. Selker EU (1991) Repeat-induced point mutation and DNA methylation. In: Bennet JW, Lasure LL (eds) More gene manipulations in fungi. Academic Press, San Diego, pp 258–265

    Google Scholar 

  11. Springer ML (1993) Genetic control of fungal differentiation: the three sporulation pathways of Neurospora crassa. BioEssays 15:365–374

    Article  PubMed  CAS  Google Scholar 

  12. Springer ML, Yanofsky C (1989) A morphological and genetic analysis of conidiophore development in Neurospora crassa. Genes Dev 3:559–571

    Article  PubMed  CAS  Google Scholar 

  13. Beth Din A, Specht CA, Robbins PW, Yarden O (1996) chs-4, a class IV chitin synthase from Neurospora crassa. Mol. Gen. Genet. 250:214–222

    Google Scholar 

  14. Beth Din A, Yarden O (1994) The Neurospora crassa chs-2 gene encodes a non-essential chitin synthase. Microbiology 140:2189-2

    Article  Google Scholar 

  15. Chunag JS, Schekman RW (1996) Differential trafficking and timed localization of two chitin synthase proteins, Chs2p and Chs3p. J Cell Biol 135:597–610

    Article  Google Scholar 

  16. Gooday GW (1995) The dynamics of hyphal growth. Mycol Res 99:385–394

    Article  Google Scholar 

  17. Sietsma JH, Beth Din A, Ziv V, Sjollema KA, Yarden O (1996) Membranous vesicles (chitosomes) are involved in chitin synthase compartmentalization and trafficking in Neurospora crassa. Microbiology 142:1591–1596

    Article  PubMed  CAS  Google Scholar 

  18. Wessels JGH (1990) Role of cell wall architecture in fungal tip growth generation. In: Heath IB (ed) Tip growth in plant and fungal cells. Academic Press, New York, pp 1–29

    Google Scholar 

  19. Yarden O, Yanofsky C (1991) Chitin synthase 1 plays a major role in cell wall biogenesis in Neurospora crassa. Genes Dev 5:2420–2430

    Article  PubMed  CAS  Google Scholar 

  20. Glass NL, Staben C (1990) Genetic control of mating in Neurospora crassa. Semin Dev Biol 1:177–184

    Google Scholar 

  21. Raju NB (1992) Genetic control of the sexual cycle in Neurospora. Mycol Res 96:241–262

    Article  Google Scholar 

  22. Springer ML (1993) Genetic control of fungal differentiation: the three sporulation pathways of Neurospora crassa. BioEssays 15:365–374

    Article  PubMed  CAS  Google Scholar 

  23. Ebbole DJ (1996) Morphogenesis and vegetative differentiation in filamentous fungi. J Genet 75:361–374

    Article  Google Scholar 

  24. Keller NP, Hohn TM(1997) Metabolic pathway gene clusters in filamentous fungi. Fung Genet Biol 21:17–29

    Article  CAS  Google Scholar 

  25. Russo VEA, Pandit NN (1992) Development in Neurospora crassa. In: Russo VEA, Brody S, Cove D, Ottolenghi S (eds) Development the molecular genetic approach. Springer, Berlin Heidelberg New York, pp 88–102

    Google Scholar 

  26. Bell-Pedersen D, Dunlap JC, Loros JJ (1992) The Neurospora circadian clock-controlled gene, ccg-2, is allelic to eas and encodes a fungal hydrophobin required for formation of the conidial rodlet layer. Genes Dev 6:2382–2394

    Article  PubMed  CAS  Google Scholar 

  27. Berlin V, Yanofsky C (1985 a) Protein changes during the asexual cycle of Neurospora crassa. Mol Cell Biol 5:839–848

    PubMed  CAS  Google Scholar 

  28. Berlin V, Yanofsky C (1985 b) Isolation and characterization of genes differentially expressed during conidiation of Neurospora crassa. Mol Cell Biol 5:849–855

    PubMed  CAS  Google Scholar 

  29. Corrochano LM, Lauter F-R, Ebbole D, Yanofsky C (1995) Light and developmental regulation of the gene con-10 of Neurospora crassa. Dev Biol 167:190–200

    Article  PubMed  CAS  Google Scholar 

  30. Ebbole DJ (1997) Hydrophobins and fungal infection of plants and animals. Trends Microbiol 5:405–408

    Article  PubMed  CAS  Google Scholar 

  31. Ebbole DJ (1996) Morphogenesis and vegetative differentiation in filamentous fungi. J Genet 75:361–374

    Article  Google Scholar 

  32. Lauter F-R, Russo VEA, Yanofsky C (1992) Developmental and light regulation of eas, the structural gene for the rodlet protein of Neurospora. Genes Dev 6:2372–2381

    Article  Google Scholar 

  33. Lauter F-R, Yanofsky C (1993) Day/night and circadian rhythem control of con gene expression in Neurospora. Proc Natl Acad Sci USA 90:8249–8253

    Article  PubMed  CAS  Google Scholar 

  34. Selitrennikoff CP (1976) Easily-wettable, a new mutant. Neurospora Newsl 23:23

    Google Scholar 

  35. Springer ML, Yanofsky C (1992) Expression of con genes along the three sporulation pathways of Neurospora crassa. Genes Dev 6:1052–1057

    Article  PubMed  CAS  Google Scholar 

  36. Alex LA, Borkovich KA, Simon MI (1996) Hyphal development in Neurospora crassa: involvement of a twocomponent histidine kinase. Proc Natl Acad Sci USA 93:3416–3421

    Article  PubMed  CAS  Google Scholar 

  37. Dickman MB, Yarden O (1999) Serine/threonine protein kinases and phosphatases in filamentous fungi. Fung Genet Biol 26:99–117

    Article  CAS  Google Scholar 

  38. Lauter F-R, Marchfelder U, Russo VEA, Yamashiro CT, Yatzkan E, Yarden O (1998) Photoregulation of cot-1, a kinase-encoding gene involved in hyphal growth in Neurospora crassa. Fung Genet Biol 23:300–310

    Article  CAS  Google Scholar 

  39. Plamann M, Minke PF, Tinsley JH, Bruno KS (1994) Cytoplasmic dyanin and actin-related protein Arpl are required for normal nuclear distribution in filamentous fungi. J Cell Biol 127:139–149

    Article  PubMed  CAS  Google Scholar 

  40. Vierula PJ (1996) The genetics of morphogenesis in Neurospora crassa. In: Chiu SW, Moore D (eds) Patterns in fungal development. Cambridge University Press, Cambridge, pp 87–104

    Google Scholar 

  41. Stark MJ (1996) Yeast protein serine/threonine phosphatases: multiple roles and diverse regulation. Yeast 12:1647–1675

    Article  PubMed  CAS  Google Scholar 

  42. Xu JR, Hamer JE (1996) MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev 10:2692–2706

    Google Scholar 

  43. Yarden O, Plamann M, Ebbole DJ, Yanofsky C (1992) cot-1, a gene of Neurospora crassa required for hyphal elongation, encodes a protein kinase. EMBOJ 11:2159–2166

    CAS  Google Scholar 

  44. Assaad FF, Tucker KL, Singer ER (1993) Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis. Plant Mol Biol 22:1067–1085

    Article  PubMed  CAS  Google Scholar 

  45. Chernov AV, Vollmayr P, Walter J, Trautner TA (1997) Masc2, a C5-DNA-methyltransferase from Ascobulus immersus with similarity to methyltransferases of higher organisms. J Biol Chem 378:1467–1473

    Article  CAS  Google Scholar 

  46. Cogoni C, Irelan JT, Schumacher M, Schmidhauser TJ, Selker EU, Macino G (1996) Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBOJ 15:3153–3163

    CAS  Google Scholar 

  47. Malagnac F, Wendel B, Goyon C, Faugeron G, Zickler D, Rossignol J-L, Noyer-Weidner M, Vollmayr P, Trautner TA, Walter J (1997) A gene essential for de novo methylation and development in Ascobulus reveals a novel type of eukaryotic DNA methyltransferase structure. Cell 91:281–290

    Article  PubMed  CAS  Google Scholar 

  48. Napoli C, Lemieux C, Jorgensen R (1990) Introduction of a chimeric chalcone synthase into petunia reults in reversible co-suppression of homologous genes in trans. Plant Cell 2:279–289

    Article  PubMed  CAS  Google Scholar 

  49. Pandit NN, Russo VEA (1992) Reversible inactivation of a foreign gene, hph, during the asexual cycle in Neurospora crassa transformants. Mol Gen Genet 234:412–422

    Article  PubMed  CAS  Google Scholar 

  50. Russell PJ, Rodland KD, Rachlin EM, McClosky JA (1987) Differential DNA methylation during the vegetative life cycle of Neurospora crassa. J Bacteriol 169:2902–2905

    PubMed  CAS  Google Scholar 

  51. Russo VEA, Martienssen RA, Riggs AD (1996) Epigenetic mechanisms of gene regulation, Cold Spring Harbor Laboratory Press, Cold Spring Harbor

    Google Scholar 

  52. Selker EU (1991) Repeat-induced point mutation and DNA methylation. In: Bennet JW, Lasure LL (eds) More gene manipulations in fungi. Academic Press, San Diego, pp 258–265

    Google Scholar 

  53. Waddington CH (1956) Principles of embryology. Macmillan, New York

    Google Scholar 

  54. Adams TH (1994) A sexual sporulation in higher fungi. In: Gow NAR, Gadd GM (eds) The growing fungus. Chapman and Hall, London, pp 367-382

    Google Scholar 

  55. Degli-Innocenti F, Russo VEA (1984) Genetic analysis of blue light induced response in Neurospora crassa. In: Senger H (ed) Blue light effects in biological systems. Springer, Berlin Heidelberg New York, pp 214–219

    Google Scholar 

  56. Ricci M, Krappmann D, Russo VEA (1991) Nitrogen and carbon starvation regulate conidia and protoperithecia formation of Neurospora crassa grown on solid media. Fungal Genet Newsl 38:87–88

    Google Scholar 

  57. Sokolowsky VY, Lauter F-R, Mueller-Roeber B, Ricci M, Schmidhauser TJ, Russo VEA (1992) Nitrogen regulation of blue-light-regulated genes in Neurospora crassa. J Gen Microbiol 138:2045–2049

    Google Scholar 

  58. Springer ML (1993) Genetic control of fungal differentiation: the three sporulation pathways of Neurospora crassa. BioEssays 15:365–374

    Article  PubMed  CAS  Google Scholar 

  59. Ballario P, Vittorioso P, Magrelli A, Talora C, Cabibbo A, Macino G (1996) White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein. EMBOJ 15:1650–1657

    CAS  Google Scholar 

  60. Clutterbuck AJ, Timberlake WE (1992) Genetic regulation of sporulation in the fungus Aspergillus nidulans. In: Russo VEA, Brody S, Cove D, Ottolenghi S (eds) Development the molecular genetic approach. Springer, Berlin Heidelberg New York, pp 103-120

    Google Scholar 

  61. Lauter F-R (1996) Molecular genetics of fungal photobiology. J Genet 75:375–386

    Article  CAS  Google Scholar 

  62. Linden H, Macino G (1997) White collar 2, a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa. EMBOJ 16:98–109

    Article  CAS  Google Scholar 

  63. Perkins DD, Radford A, Newmeyer D, Bjorkman M (1982) Chromosomal loci of Neurospora crassa. Microbiol Rev 46:426–570

    PubMed  CAS  Google Scholar 

  64. Russo VEA, Pandit NN (1992) development in Neurospora crassa. In: Russo VEA, Brody S, Cove D, Ottolenghi S (eds) Development the molecular genetic approach. Springer, Berlin Heidelberg New York, pp 88–102

    Google Scholar 

  65. Went FAFC (1904) Uber den Einfluss des Lichtes auf die Entstehung des Carotins und die Zersetzung der Enzyme. Reel Trav Bot Neerl 1:106–119.

    Google Scholar 

Download references

Authors
  1. Oded Yarden
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vincenzo E. A. Russo
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. MPI für Molekulare Genetik, Ihnestraße 73, D-14195, Berlin, Germany

    Vincenzo E. A. Russo

  2. Leeds Institute of Plant Biochemistry and Agriculture, University of Leeds, Leeds, LS29JT, Great Britain

    David J. Cove

  3. Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, 80302, CO, USA

    Lois G. Edgar

  4. Whitehead Institute, Nine Cambridge Center, Cambridge, 02141, MA, USA

    Rudolf Jaenisch

  5. MPI für Züchtungsforschung, Carl-von-Linné-Weg 10, Köln, D-50829, Germany

    Francesco Salamini

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin · Heidelberg New York

About this chapter

Cite this chapter

Yarden, O., Russo, V.E.A. (1999). Genetic and Environmental Influence on Development of the Filamentous Fungus Neurospora crassa . In: Russo, V.E.A., Cove, D.J., Edgar, L.G., Jaenisch, R., Salamini, F. (eds) Development. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59828-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59828-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64141-1

  • Online ISBN: 978-3-642-59828-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation