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Autologous Peripheral Blood Stem Cell Transplantation in Childhood Metastatic Osteosarcoma

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Transplantation in Hematology and Oncology

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Abstract

Over the past few years the outcome of patients with high grade osteosarcoma (OST) improved dramatically, with survival rates rising from 15% up to 70% [1]. The relatively large series of subjects reported by the Rizzoli Institute and Scandinavian Sarcoma Group confirm that the results of treatment improve with increasing aggressiveness of the chemotherapy, showing a dose-response relationship regarding tumor response and survival [2,3]. By contrast, patients with overt metastatic disease at diagnosis as well as those with disease recurrence have a poor prognosis [1–3].

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References

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Author information

Authors and Affiliations

  1. Department of Pediatric Oncology, University of Turin, Italy

    R. Miniero, A. Busca, A. Brach del Prever, E. Vassallo, F. Fagioli, E. Incarbone & F. Nesi

  2. Istituto Ortopedico Rizzoli, Bologna, Italy

    G. Bacci, P. Picci & E. Madon

Authors
  1. R. Miniero
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  2. A. Busca
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  3. A. Brach del Prever
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  4. E. Vassallo
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  5. F. Fagioli
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  6. E. Incarbone
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  7. F. Nesi
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  8. G. Bacci
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  9. P. Picci
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  10. E. Madon
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine Hematology/Oncology, University of Muenster, Albert-Schweitzer-Straße 33, 48129, Muenster, Germany

    W. E. Berdel (Prof. Dr. med.), Th. Büchner (Prof. Dr. med.), J. Kienast  & J. Van De Loo (Prof. Dr. med.) (Prof. Dr. med.),  (Prof. Dr. med.),  &  (Prof. Dr. med.)

  2. Department of Pediatrics, University of Münster, Albert-Schweitzer-Straße 33, 48129, Muenster, Germany

    H. Jürgens (Prof. Dr. med.), J. Ritter (Prof. Dr. med.) & J. Vormoor (Dr. med.) (Prof. Dr. med.),  (Prof. Dr. med.) &  (Dr. med.)

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© 2000 Springer-Verlag Berlin Heidelberg

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Miniero, R. et al. (2000). Autologous Peripheral Blood Stem Cell Transplantation in Childhood Metastatic Osteosarcoma. In: Berdel, W.E., et al. Transplantation in Hematology and Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59592-9_33

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  • DOI: https://doi.org/10.1007/978-3-642-59592-9_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64041-4

  • Online ISBN: 978-3-642-59592-9

  • eBook Packages: Springer Book Archive

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