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Normal and Leukemic Human Stem Cells

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Transplantation in Hematology and Oncology

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Abstract

With the dramatic increase of interest aimed at manipulating and transplanting normal human stem cells for clinical applications and for purging or eradicating leukemic stem cells, there is great need for in vivo assays for normal and leukemic human stem cells. The recent development of methods to transplant human hematopoietic cells into immune-deficient mice provides an important approach to characterize stem cells and to develop animal models for hematopoietic diseases including leukemia

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Authors and Affiliations

  1. Department of Genetics, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada

    John E. Dick

  2. Department of Molecular and Medical Genetics, University of Toronto, Canada

    John E. Dick

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Editors and Affiliations

  1. Department of Internal Medicine Hematology/Oncology, University of Muenster, Albert-Schweitzer-Straße 33, 48129, Muenster, Germany

    W. E. Berdel (Prof. Dr. med.), Th. Büchner (Prof. Dr. med.), J. Kienast  & J. Van De Loo (Prof. Dr. med.) (Prof. Dr. med.),  (Prof. Dr. med.),  &  (Prof. Dr. med.)

  2. Department of Pediatrics, University of Münster, Albert-Schweitzer-Straße 33, 48129, Muenster, Germany

    H. Jürgens (Prof. Dr. med.), J. Ritter (Prof. Dr. med.) & J. Vormoor (Dr. med.) (Prof. Dr. med.),  (Prof. Dr. med.) &  (Dr. med.)

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© 2000 Springer-Verlag Berlin Heidelberg

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Dick, J.E. (2000). Normal and Leukemic Human Stem Cells. In: Berdel, W.E., et al. Transplantation in Hematology and Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59592-9_3

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  • DOI: https://doi.org/10.1007/978-3-642-59592-9_3

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