Abstract
Fluorescence correlation spectroscopy (FCS) has been developed into a versatile, specific and sensitive method applicable to the life sciences. DNADNA, protein-DNA, ligand-receptor, dye-DNA, and protein-protein interactions, among others, have been successfully analyzed using FCS [10.1–10.11]. Recently, special applications in the field of high throughput pharmaceutical screening have been described [10.12,10.13].
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References
J. Widengren and R. Rigler: Cell Mol. Biol. 44, 857 79 (1998)
U. Kettling, A. Koltermann, P. Schwille, and M. Eigen: Proc. Natl. Acad. Sci. USA 95, 1416–1420 (1998)
P. Schwille, F.-J. Meyer-Almes, and R. Rigler: Biophys. J. 72, 1878 (1997)
F.-J. Meyer-Almes, K. Wyzgol, and M.J. Powell: Biophys. Chem. 75, 151–160 (1998)
R. Rigler, Z. Földes-Papp, F.-J. Meyer-Almes, C. Sammet, M. Völcker, and A. Schnetz: J. of Biotechnology 63, 97–109 (1998)
N.G. Walter, P. Schwille, and M. Eigen: Proc. Natl. Acad. Sci. USA 93, 12805–12810 (1996)
M. Pitschke, R. Prior, M. Haupt, and D. Riesner: Nature Medicine4, 832–34 (1998)
P. Schwille, J. Bieschke, and F. Oehlenschlager: 66, 211–28 (1997)
S. Maiti, U. Haupts, and W.W. Webb: Proc. Natl. Acad. Sci. USA. 94, 11753–57 (1997)
A. Koltermann, U. Kettling, J. Bischke, T. Winkler, and M. Eigen: Proc. Natl. Acad. Sci. USA 95, 1421–1426 (1998)
T. Winkler, U. Kettling, A. Koltermann, and M. Eigen: Proc. Natl. Acad. Sci. USA 96, 1375–8 (1999)
S. Sterrer and K. Henco: J. Receptor Signal Transduction Research 17, 511–520 (1997)
M. Auer, K.J. Moore, F.-J. Meyer-Almes, R. Guenther, A.J. Pope, and K.A. Stoeckli: Drug Discovery Today 3, 457–465 (1998)
R. Uauy, D.L. Shapiro, B. Smith, and J.B. Warshaw: Pediatrics 55, 595–598 (1975)
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Meyer-Almes, F.J. (2001). Nanoparticle Immunoassays: A new Method for Use in Molecular Diagnostics and High Throughput Pharmaceutical Screening based on Fluorescence Correlation Spectroscopy. In: Fluorescence Correlation Spectroscopy. Springer Series in Chemical Physics, vol 65. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59542-4_10
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DOI: https://doi.org/10.1007/978-3-642-59542-4_10
Publisher Name: Springer, Berlin, Heidelberg
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