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The Pineal Gland, Melatonin, and Neoplastic Growth: Morphological Approach

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The Pineal Gland and Cancer

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Abstract

The relationship between the pineal gland and neoplastic growth was suggested as early as 1929. However, real progress in this area of research has only been made in the last two decades. Although studies on the link between the pineal gland and tumorigenesis do not always yield consistent results, the majority of reports have pointed to the oncostatic action of the pineal gland. However, very few studies on tumor morphology after pinealectomy or melatonin administration and on pineal morphology in tumor-bearing animals have been performed. In this review, the data (including the author’s own) on morphological aspects of the pineal gland and melatonin influence on neoplastic growth as well as on pineal morphology in tumor-bearing animals are presented.

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Authors
  1. Michal Karasek
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Editor information

Editors and Affiliations

  1. Centre for Research in Medical and Natural Sciences, University of Tübingen, Ob dem Himmelreich 7, Tübingen, 72074, Germany

    Christian Bartsch  & Hella Bartsch  & 

  2. Laboratory of Experimental Neuroendocrinology/Oncology, Bassett Research Institute, One Atwell Road, Cooperstown, NY, 13326, USA

    David E. Blask Ph.D.,M.D. (Senior Research Scientist) (Senior Research Scientist)

  3. Department of Physiology Faculty of Medicine, University of Buenos Aires, Paraguay 2155, Buenos Aires, 121, Argentina

    Daniel P. Cardinali M.D.,Ph.D.

  4. WJB Dorn VA Medical Center, University of South Carolina, 6439 Garners Ferry Road, Columbia, SC, 29209, USA

    William J. M. Hrushesky M.D. (Director of Research (151) (Director of Research (151)

  5. Institute of Physiological Chemistry, University of Tübingen, Hoppe-Seyler-Str. 4, Tübingen, 72076, Germany

    Dieter Mecke (Director) (Director)

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© 2001 Springer-Verlag Berlin Heidelberg

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Karasek, M. (2001). The Pineal Gland, Melatonin, and Neoplastic Growth: Morphological Approach. In: Bartsch, C., Bartsch, H., Blask, D.E., Cardinali, D.P., Hrushesky, W.J.M., Mecke, D. (eds) The Pineal Gland and Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59512-7_9

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  • DOI: https://doi.org/10.1007/978-3-642-59512-7_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64003-2

  • Online ISBN: 978-3-642-59512-7

  • eBook Packages: Springer Book Archive

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