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Neuroimmunomodulation Via the Autonomic Nervous System

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The Pineal Gland and Cancer

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Abstract

The existence of an intense dialogue between the brain and the immune system is well-established, and the role of the autonomic nervous system as the translator for both systems is becoming increasingly evident. The development and functions of lymphocytes are influenced by transmitters of the autonomic nervous system. On the other hand, the “feedback” of the activated immune system to the brain is also modulated by autonomic mechanisms. Finally, besides expressing adrenergic and cholinergic receptors, lymphocytes were recently shown to synthesize and release catecholamines and acetylcholine, pointing to a possible role of these mediators in the intrinsic regulation of the immune system. In this review, we will discuss data to these points as obtained in experimental studies in the rat model.

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Authors
  1. Konrad Schauenstein
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  2. Ingo Rinner
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  3. Peter Felsner
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  4. Albert Wölfler
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  5. Helga S. Haas
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  6. J. Ross Stevenson
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  7. Werner Korsatko
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  8. Peter M. Liebmann
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Editor information

Editors and Affiliations

  1. Centre for Research in Medical and Natural Sciences, University of Tübingen, Ob dem Himmelreich 7, Tübingen, 72074, Germany

    Christian Bartsch  & Hella Bartsch  & 

  2. Laboratory of Experimental Neuroendocrinology/Oncology, Bassett Research Institute, One Atwell Road, Cooperstown, NY, 13326, USA

    David E. Blask Ph.D.,M.D. (Senior Research Scientist) (Senior Research Scientist)

  3. Department of Physiology Faculty of Medicine, University of Buenos Aires, Paraguay 2155, Buenos Aires, 121, Argentina

    Daniel P. Cardinali M.D.,Ph.D.

  4. WJB Dorn VA Medical Center, University of South Carolina, 6439 Garners Ferry Road, Columbia, SC, 29209, USA

    William J. M. Hrushesky M.D. (Director of Research (151) (Director of Research (151)

  5. Institute of Physiological Chemistry, University of Tübingen, Hoppe-Seyler-Str. 4, Tübingen, 72076, Germany

    Dieter Mecke (Director) (Director)

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© 2001 Springer-Verlag Berlin Heidelberg

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Schauenstein, K. et al. (2001). Neuroimmunomodulation Via the Autonomic Nervous System. In: Bartsch, C., Bartsch, H., Blask, D.E., Cardinali, D.P., Hrushesky, W.J.M., Mecke, D. (eds) The Pineal Gland and Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59512-7_18

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  • DOI: https://doi.org/10.1007/978-3-642-59512-7_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64003-2

  • Online ISBN: 978-3-642-59512-7

  • eBook Packages: Springer Book Archive

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