Zusammenfassung
Dieser Beitrag fokussiert trotz seiner Überschrift auf die „neuen“ Antidepressiva. Dennoch sollen für den fachfremden Leser hier auch die wichtigsten Punkte zu den klassischen Antidepressiva kurz zusammengefasst werden.
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Literatur
Angst J, Baumann M, Hippius H, Rothweiler R (1974) Clinical aspects of resistance to imipramine therapy. Pharmakopsychiat 7: 211–216
Ansseau M, Darimont P, Lecoq A et al. (1994) Controlled comparison of Nefazodone and Amitriptyline in major depressive inpatients. Psychopharmacology 115: 254–260
Baldwin D, Rudge S (1994) Tolerability of Moclobemide. Rev Contemp Pharmacother 5: 57–65
Ban TA, Graszner P, Aguglia E et al. (1998) Clinical efficacy of reboxetine: A comparative study with desipramine, with methological considerations. Human Psychopharmacol 13: 29–39
Beckmann H (1981) Pharmacological treatment of affective disorders. Nervenarzt 52: 135–146
Berzewski H, Van Moffaert M, Gagiano CA (1997) Efficacy and tolerability of reboxetine compared with imipramine in a double-blind study in patients suffering from major depressive episodes. Eur Neuropsychopharmacol 7 [Suppl 1]: 37–47
Bolden-Watson C, Richelson E (1993) Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes. Life Sci 52 (12): 1023–1029
Boudriot S (2001) Wirksamkeitsnachweis in klinischen Studien: Vergleich der neueren Antidepressiva Reboxetin, Nefazodon and Mirtazapin. Inaugural-Dissertation. Medizinische Fakultät der Eberhard-Karls-Universität Tübingen
Bremner JD, Smith WT (1996) ORG 3770 VS Amitriptyline in the continuation treatment of depression: A placebo controlled trial. Eur J Psychiat 10: 5–15
Breyer-Pfaff U, Gaertner HJ (1987) Antidepressiva. Pharmakologie, therapeutischer Einsatz and Klinik der Depression. Wissenschaftliche Verlagsgesellschaft, Stuttgart
Bruijn JA, Moleman P, Mulder PGH, Van den Broek WW, Van Hulst AM, Van der Mast RC, Van de Wetering BJM (1996) A double-blind, fixed blood-level study comparing mirtazapine with imipramine in depressed in-patients. Psychopharmacology 127: 231–237
Burrows GD, Maguire KP, Norman TR (1998) Antidepressant efficacy and tolerability of the selective norepinephrine reuptake inhibitor Reboxetine: A review. J Clin Psychiatry 59 [Suppl 14]: 4–7
Chambers CD, Johnson KA, Dick LM, Felix RJ, Jones KL (1996) Birth outcomes in pregnant women taking fluoxetine. N Engl J Med 335 (14): 1010–1015
Claghorn JL, Lesem MD (1995) A double-blind placebo-controlled study of org 3770 in depressed patients. J Affect Disorders 34: 165–171
Clerc GE, Ruimy P, Verdeau-Palles J (1994) A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for major depression and melancholia. Int Clin Psychopharmacol 9: 139–143
Cohen LS, Sichel DA, Robertson LM, Heckscher E, Rosenbaum JF (1995) Postpartum prophylaxis for women with bipolar disorder. Am J Psychiatry 152 (11): 1641–1645
D’Amico MF, Roberts DL, Robinson DS, Schwiederski UE, Copp J (1990) Placebo-controlled dose-ranging trial designs in phase II developement of nefazodone. Psychopharmacol Bull 26: 147–150
Ellingrod VL, Perry PJ (1995) Nefazodone a new antidepressant. Am J Health-Syst Pharm 52: 2799–2812
Entsuah AR, Rudolph RL, Hackett D et al. (1996) Efficacy of venlafaxine and placebo during long-term treatment of depression: a pooled analysis of relapse rates. Int Clin Psychopharmacol 11: 137–45
Feiger A, Kiev A, Shrivastava RK, Wisselink PG, Wilcox CS (1996) Nefazodone versus sertaline in outpatients with major depression: Focus on efficacy, tolerability and effects on sexual function and satisfaction. J Clin Psychiatry 57 [Suppl]: 53–62
Feighner JP, Pambakian R, Fowler RC, Boyer WF, D’Amico MF (1989) A comparison of nefazodone, imipramine and placebo in patients with moderate to severe depression. Psychopharmacol Bull 25: 219–221
Ferrier IN (1999) Treatment of major depression: Is improvement enough? J Clin Psychiatry 60 [Suppl 6]: 10–14
Gillin JC, Rapaport M, Erman MK et al. (1997) A comparison of nefazodone and fluoxetine on mood and on objective, subjective, and clinician-ratedd measures of sleep in depressed patients: a double-blind, 8-week clinical trial. J Clin Psychiatry 58: 185–92
Gleiter ChH, Volz HP, Möller HJ (1999) Serotonin-Wiederaufnahmehemmer. Pharmakologie and therapeutischer Einsatz. Wissenschaftliche Verlagsgesellschaft, Stuttgart
Halikas JA (1995) Org 3770 (Mirtazapine) versus Trazodone: A placebo controlled trial in depressed elderly patients. Human Psychopharmacol 10: S215–S133
Hoyberg OJ,Maragakis B, Mullin J (1996) A double-blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients. Acta Psychiatr Scand 93: 184–90
Hyttel J (1994) Pharmacological characterization of selective serotonin reuptake inhibitors (CSSRIs). Int Clin Psychopharmacol 9 Suppl 1: 19–26
Kasper S, Praschak-Rieder N, Tauscher J et al. (1997) A risk-benefit assessment of mirtazapine in the treatment of depression. Drug Saf 17: 251–64
Kasper S (1995) Clinical efficacy of mirtazapine: a review of meta-analysis of pooled data. Int Clin Psychopharmacol 10 [Suppl 4]: 25–35
Kent J (2000) SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression. Lancet 355: 911
Massana J, Möller H-J, Burrows GD, Montenegro RM (1999) Reboxetine: A double-blind comparison with fluoxetine in major depressive disorder. International Clinical Psychopharmacology 14: 73–80
Montgomery SA, Reimitz PE, Zivkov M (1998) Mirtazapine versus amitriptyline in a long-term treatment od depression: a double-blind, placebo-controlled study. Int Clin Psychopharmacol 18: 63–73
Montgomery SA (1997) Is there a role for a pure noradrenergic drug in the treatment of depression? European Neuropsychopharmacology 7 [Suppl]: 3–9
Montgomery SA (1998) Chairman’s overview. The place of Reboxetne in antidepressant therapy. J Clin Psychiatry 59 [Suppl]: 26–29
Nulman I, Rovet J, Stewart DE, Wolpin J, Gardner HA, Theis JG, Kuhn N, Koren G (1997) Neurodevelopment of children exposed in utero to antidepressant drugs. N Engl J Med 336 (4): 258–262
Reynaert C, Janne P, Zdanowicz N mit der Venlafaxine 600A-GAP-BE Study Group (2000) Cliniques Universitaires de Montgodinne, Yvoir, Belgium, Wyeth Lederle Belgium, Louvain-la Neuve, Belgium. Poster. 13. ECNP Kongress, München 9.-13. 9. 2000
Schmauss M, Kapfhammer HP, Meyr P, Hoff P (1988) Combined MAO-inhibitor and tri- (tetra) cyclic antidepressant treatment in therapy resistant depression. Prog Neuropsychopharmacol Biol Psychiatry 12 (4): 523–532
Smith WT, Glaudin V, Panagides J, Gilvary E (1990) Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder. Psychopharmacology Bull 26: 191–196
Thase ME (1997) Efficacy and tolerability of once-daily venlafaxine extended release (XR) in outpatients with major depression: the Venlafaxine XR 209 Study Group. J Clin Psychiatry 14: 392–398
Versiani M, Amin M, Chouinard G (2000) Double-blind, placebo-controlled study with Reboxe- tine in inpatients with severe major depressive disorder. J Clin Psychopharmacol 20: 28–34
Versiani M, Mehilane L, Graszner P, Arnaud-Castiglioni R (1999) Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term-treatment of major depressive disorder. J Clin Psychiatry 60 (6): 400–406
Wheatly DP, Van Moffaert M, Timmerman L, Kremer ME (1998) Mirtazapine: Efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive Disorder. J Clin Psychiatry 59: 306–312
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Gaertner, H.J., Boudriot, S., Gaertner, I. (2001). Alte und neue Antidepressiva. In: Batra, A., Buchkremer, G. (eds) Die therapeutische Vielfalt in der Depressionsbehandlung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59494-6_3
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DOI: https://doi.org/10.1007/978-3-642-59494-6_3
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