Abstract
We recently reported population data on the incidence and outcomes of pediatric sepsis and multiple organ failure (MOF) in the US in abstract form at two meetings [1, 2]. The data from 1995 hospital discharge summaries was linked to 1995 US census data and severe sepsis was defined as the presence of one or more organ failures and bacterial or fungal disease. Compared to adults, there was an age-specific decreased incidence in severe sepsis (5.3/1000 <1 year, 0.2/1000 5–14 years, vs 5.3/1000 60–64 years, and 26.2/1000 ≥ 85 years). Mortality rates also decreased in an age-specific manner (13% at < 1 year, ≤ 10% at 1–14 years, vs 22% at 30–35 years, and 37% at ≥ 85 years). The 10.3% overall mortality rate in infants and children was markedly reduced compared to the 97% mortality rate reported by the University of Minnesota Hospitals in children with Gram-negative bacteremia in 1967 [3]. Despite this remarkable reduction in mortality, the data suggest that more children in the US die from severe sepsis than die from cancer.
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Carcillo, J.A. (2001). Pediatric Sepsis and Multiple Organ Failure at the Millenium: A US Perspective. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2001. Yearbook of Intensive Care and Emergency Medicine 2001, vol 2001. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59467-0_3
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DOI: https://doi.org/10.1007/978-3-642-59467-0_3
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