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Lactate, Lactate/Pyruvate Ratio, Low Tissue Perfusion and Outcome

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 2001

Part of the book series: Yearbook of Intensive Care and Emergency Medicine 2001 ((YEARBOOK,volume 2001))

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Abstract

The measurement of arterial lactate concentrations is of clinical relevance because hyperlactatemia can be both a sign of inadequate perfusion and a predictor of a worse outcome. The relationship between inadequate tissue perfusion and hyperlactatemia in clinical shock is accepted by most clinicians. Nevertheless, the etiology of hyperlactatemia is multifactorial. In addition to anaerobic glycolysis due to hypoperfusion, increased aerobic glycolysis in hypermetabolic states [1] or in patients treated with catecholamines [2], metabolic alterations in sepsis [1] and hyperventilation [3] may be associated with hyperlactatemia.

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Authors
  1. S. M. Jakob
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  2. M. Suistomaa
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  3. J. Takala
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2001 Springer-Verlag Berlin Heidelberg

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Jakob, S.M., Suistomaa, M., Takala, J. (2001). Lactate, Lactate/Pyruvate Ratio, Low Tissue Perfusion and Outcome. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2001. Yearbook of Intensive Care and Emergency Medicine 2001, vol 2001. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59467-0_23

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  • DOI: https://doi.org/10.1007/978-3-642-59467-0_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41407-0

  • Online ISBN: 978-3-642-59467-0

  • eBook Packages: Springer Book Archive

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