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Introduction

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Part of the book series: Advances in Anatomy Embryology and Cell Biology ((ADVSANAT,volume 165))

Abstract

In the mature brain, calcium ions play pivotal roles in transmembrane and intracellular transmission of signals. Thus, calcium is involved in numerous neuronal functions including neurotransmitter release, enzyme regulation, modulation of neuronal excitability, gene expression, microtubular transport, or synaptic plasticity (Miller 1991). Many of these calcium-dependent processes are mediated or modulated by a number of cytosolic calcium-binding proteins (CaBPs). All nerve cells contain the calcium-binding protein calmodulin. Other CaBPs are restricted to certain nerve cell types, i.e., parvalbumin (PV), calbindin (CB) and calretinin (CR) (Baimbridge et al. 1992).

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© 2002 Springer-Verlag Berlin Heidelberg

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Ulfig, N. (2002). Introduction. In: Calcium-Binding Proteins in the Human Developing Brain. Advances in Anatomy Embryology and Cell Biology, vol 165. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59425-0_1

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  • DOI: https://doi.org/10.1007/978-3-642-59425-0_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-43463-4

  • Online ISBN: 978-3-642-59425-0

  • eBook Packages: Springer Book Archive

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