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Control of Japanese Encephalitis in Japan: Immunization of Humans and Animals, and Vector Control

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Japanese Encephalitis and West Nile Viruses

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 267))

Abstract

Japanese encephalitis (JE) is a serious acute viral encephalitis with high case fatality; approximately half of the survivors suffer from grave sequelae accompanied by neuropsychiatric disorders. Its causative agent, JE virus, is a member of the genus Flavivirus of the family Flaviviridae, and is a typical mosquito-borne arbovirus according to its mode of transmission. Its principal vector is Culex tritaeniorhynchus and related species, and its major amplifier is swine. Humans are relatively insensitive to JE virus and are considered as dead-end hosts in the transmission cycle. Based on the mode of transmission, three strategies have been considered for the control of human JE: (1) vector control, (2) swine immunization, and (3) human immunization. All of them have been carried out in the epidemiological settings of Japan, and the findings are described briefly below.

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Author notes

  1. A. Igarashi

    Present address: School of Social Welfare Planning, Department of Social Welfare, Kyushu University of Health and Welfare, Takahashi Educational Institutions, 1714-1 Yoshino-cho, Nobeoka City, Miyazaki, 882-8508, Japan

Authors and Affiliations

  1. Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan

    A. Igarashi

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  1. A. Igarashi
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Editors and Affiliations

  1. Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia

    John S. Mackenzie

  2. Departments of Pathology and Microbiology and Immunology, School of Medicine, The University of Texas Medical Branch of Galveston, Galveston, 77555-0605, USA

    Alan D. T. Barrett

  3. Centre de Recherche Mérieux Pasteur à Lyon, 21 Avenue Tony Garnier, 69365, Lyon cedex 7, France

    Vincent Deubel

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© 2002 Springer-Verlag Berlin Heidelberg

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Igarashi, A. (2002). Control of Japanese Encephalitis in Japan: Immunization of Humans and Animals, and Vector Control. In: Mackenzie, J.S., Barrett, A.D.T., Deubel, V. (eds) Japanese Encephalitis and West Nile Viruses. Current Topics in Microbiology and Immunology, vol 267. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59403-8_7

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  • DOI: https://doi.org/10.1007/978-3-642-59403-8_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63966-1

  • Online ISBN: 978-3-642-59403-8

  • eBook Packages: Springer Book Archive

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