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Japanese Encephalitis and West Nile Viruses pp 91–103Cite as

Immune Responses to Japanese Encephalitis Virus

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 267))

Abstract

Japanese encephalitis (JE) is an acute viral encephalitis transmitted by mosquitoes, mainly Culex tritaeniorhyncus infected with JE virus. The ratio of asymptomatic to symptomatic infection is estimated to be 100:1–1000:1 (Vaughn and Hoke 1992). However, once symptoms develop, JE is a serious viral encephalitis with a high mortality rate and high percentage of neuropsychiatric sequelae (Hoke 1992; Monath and Heinz 1996; see chapter by Solomon and Vaughn, this volume). Japanese data during the past 20 years demonstrated that the mortality rate was 17%, 48% of the patients recovered with neuropsychiatric sequalae, and only 31% recovered completely (Matsunaga et al. 1999).

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Author information

Authors and Affiliations

  1. Department of Virology 1, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan

    I. Kurane

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  1. I. Kurane
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Editors and Affiliations

  1. Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia

    John S. Mackenzie

  2. Departments of Pathology and Microbiology and Immunology, School of Medicine, The University of Texas Medical Branch of Galveston, Galveston, 77555-0605, USA

    Alan D. T. Barrett

  3. Centre de Recherche Mérieux Pasteur à Lyon, 21 Avenue Tony Garnier, 69365, Lyon cedex 7, France

    Vincent Deubel

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© 2002 Springer-Verlag Berlin Heidelberg

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Kurane, I. (2002). Immune Responses to Japanese Encephalitis Virus. In: Mackenzie, J.S., Barrett, A.D.T., Deubel, V. (eds) Japanese Encephalitis and West Nile Viruses. Current Topics in Microbiology and Immunology, vol 267. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59403-8_5

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  • DOI: https://doi.org/10.1007/978-3-642-59403-8_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63966-1

  • Online ISBN: 978-3-642-59403-8

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