Fibre Type Transformation

Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 162)


Fibre type transformations are the consequence of adaptation of fibres to changed conditions. Muscle fibres are able to modify their molecular composition and their properties by altered gene expression according to the functional demands. The transformation mainly occurs in MHC isoforms. They are adaptive to the physiological changes and can transform in each other. Therefore, the MHC isoform profile is a good marker of muscle fibre type transformation. MHC isoforms expressed in a single fibre can be determined by immunohistochemical techniques. It should be noted that transformation occurs not only in MHC proteins but also in other proteins such as troponin and myosin light chains (Schiaffino and Reggiani 1996).


Fibre Type Fast Fibre Hind Limb Suspension Myosin Isoforms Fibre Type Transition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  1. 1.Faculty of Medicine Institute of AnatomyUniversity of LeipzigLeipzigGermany

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