Abstract
Fibre type transformations are the consequence of adaptation of fibres to changed conditions. Muscle fibres are able to modify their molecular composition and their properties by altered gene expression according to the functional demands. The transformation mainly occurs in MHC isoforms. They are adaptive to the physiological changes and can transform in each other. Therefore, the MHC isoform profile is a good marker of muscle fibre type transformation. MHC isoforms expressed in a single fibre can be determined by immunohistochemical techniques. It should be noted that transformation occurs not only in MHC proteins but also in other proteins such as troponin and myosin light chains (Schiaffino and Reggiani 1996).
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© 2002 Springer-Verlag Berlin Heidelberg
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Punkt, K. (2002). Fibre Type Transformation. In: Fibre Types in Skeletal Muscles. Advances in Anatomy Embryology and Cell Biology, vol 162. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59399-4_6
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DOI: https://doi.org/10.1007/978-3-642-59399-4_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-42603-5
Online ISBN: 978-3-642-59399-4
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