Skip to main content
SpringerLink
Log in

Leitlinien zur Diagnostik und Therapie von Lebermetastasen

  • Chapter
Book cover LeberMetastasen

  • 58 Accesses

Zusammenfassung

Leitlinien sind systematisch entwickelte Entscheidungshilfen für Arzt und Patient. I Leitlinien sollten von einer optimalen Behandlungsqualität ausgehen. Sie finden ihre Begründung in Situationen, bei denen eine hohe Variabilität der Behandlungsqualität besteht, wenn Maßnahmen mit fraglicher Indikation oder ohne Wirkungsnachweis zur Anwendung kommen oder bei unzureichender Verfügbarkeit begründeter Maßnahmen. In Anbetracht der zahlreichen Therapieoptionen bei Lebermetastasen war es das Ziel der Deutschen Krebsgesellschaft (DKG) in Zusammenarbeit mit der Deutschen Gesellschaft für Chirurgie (DGCH) Entscheidungshilfen für die Diagnostik und Therapie bei Patienten mit Lebermetastasen im interdisziplinären Expertenkonsens zu formuliereren (Kurzgefasste Interdisziplinäre Leitlinien 2000).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Allen-Mersh TG, Earlam S, Fordy C, Abrams K, Houghton J (1994) Quality of life and survival with continuous hepatic-artery floxuridine infusion for colorectal liver metastasis. Lancet 344: 1255–1260

    Article  PubMed  CAS  Google Scholar 

  • Bismuth H, Adam R, Levi F et al. (1996) Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg 4: 509–522

    Article  Google Scholar 

  • Butler J, Attiyeh FF, Daly JM (1986) Hepatic resection for metastases of the colon and rectum. Surgery 2: 109–113

    Google Scholar 

  • Cady B, Stone MD, McDermott Jr WV et al. (1992) Technical and biological factors in disease-free survival after hepatic resection for colorectal cancer metastases. Arch Surg 127: 561–569

    PubMed  CAS  Google Scholar 

  • Chang AE, Schneider PD, Sugarbaker PH et al. (1987) A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg 206: 685–693

    Article  PubMed  CAS  Google Scholar 

  • Charnley RM, Morris DL, Dennison AR, Amar SS, Hardcastle JD (1991) Detection of colorectal liver metastases using intraoperative ultrasonography. Br J Surg 1: 45–48

    Article  Google Scholar 

  • Civalleri D, Pector JC, Hakansson L, Arnaud JP, Duez N, Buyse M (1994) Treatment of patients with irresectable liver metastases from colorectal cancer by chemo-occlusion with degradable starch micropheres. Br J Surg 81: 1338–1341

    Article  PubMed  CAS  Google Scholar 

  • Clarke MP, Kane RA, Stelle G Jr, Hamilton ES, Ravikumar ThS, Onik G, Clouse ME (1989) Prospective comparison of preoperative imaging and intraoperative ultrasonography in the detection of liver tumors. Surgery 5: 849–855

    Google Scholar 

  • Cunningham D, Pyrhönen S, James RD et al. (1998) Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 10: 1413–1418

    Article  Google Scholar 

  • Curley SA, Izzo F, Delrio P et al. (1999) Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies. Ann Surg 1: 1–8

    Article  Google Scholar 

  • Doci F, Gennari L, Bignami P, Montalto F, Morabito A, Bozzetti F (1991) One hundred patients with hepatic metastases from colorectal cancer treated by resection: Analysis of prognostic determinants. Br J Surg 7: 797–801

    Article  Google Scholar 

  • Fernandez-Trigo V, Shamsa F, Sugarbaker PH (1995) Repeat liver resections from colorectal metastases. Surgery 3: 296–304

    Article  Google Scholar 

  • Ferrucci JT (1990) Liver tumor imaging: Current concepts. AJR Am J Roentgenol 155: 473–484

    PubMed  CAS  Google Scholar 

  • Finlay IG, McArdle CS (1986) Occult hepatic metastases in colorectal carcinoma. Br J Surg 9: 732–735

    Article  Google Scholar 

  • Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH (1998) Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer. Ann Surg 9: 309–321

    Google Scholar 

  • Foroutani A, Garland AM, Berber E et al. (2000) Laparoscopic ultrasound vs triphasic computed tomography for detecting liver tumors. Arch Surg 8: 933–938

    Google Scholar 

  • Fortner JG (1988) Recurrence of colorectal cancer after hepatic resection. Am J Surg 155: 378–382

    Article  PubMed  CAS  Google Scholar 

  • Gayowski TJ, Iwatsuki S, Madariaga JR, Selby R, Todo S, Irish W, Starzl TE (1994) Experience in hepatic resection for metastatic colorectal cancer: Analysis of clinical and pathologic risk factors. Surgery 10: 703–711

    Google Scholar 

  • Gibbs JF, Weber ThK, Rodriguez-Bigas MA, Driscoll DL, Petrelli NJ (1998) Intraoperative determinants of unresectability for patients with colorectal hepatic metastases. Am Cancer Soc 7: 1244–1249

    Google Scholar 

  • Giovannini M, Seitz JF (1994) Ultrasound-guided percutaneous alcohol injection of small liver metastases. Cancer 2: 294–297

    Article  Google Scholar 

  • Heiken JP, Weyman PhJ, Lee JKT, Balfe DM, Picus D, Brunt EM, Flye MW (1989) Detection of focal hepatic masses: Prospective evaluation with CT, delayed CT, CT during arterial portography, and MR imaging. Radiology 171: 47–51

    PubMed  CAS  Google Scholar 

  • Heisterkamp J, v. Hillegersberg R, Ijzermans JNM (1999) Interstitial laser coagulation for hepatic tumours. Br J Surg 86: 293–304

    Article  PubMed  CAS  Google Scholar 

  • Hohn DC, Stagg RJ, Friedman MA et al. (1987) The NCOG randomized trial. Proc Am Soc Oncol 6: 85

    Google Scholar 

  • Hohn DC, Stagg RJ, Friedman MA et al. (1989) A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: The Northern California Oncology Group trial. J Clin Oncol 7: 645–654

    Google Scholar 

  • Hughes KS, Simon R, Songorabodi S et al. (1986) Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of patterns of recurrence. Surgery 2: 278–284

    Google Scholar 

  • Kemeny N, Daly J. Reichman B, Geller N, Botet J, Odermann P (1987) Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma. A randomized trial. Ann Intern Med 107: 459–465

    PubMed  CAS  Google Scholar 

  • Kemeny N, Huang Y, Cohen AM et al. (1999) Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med 27: 2039–2048

    Article  Google Scholar 

  • Knol JA, Marn CS, Francis IR, Rubin JM, Bromberg J, Chang AE (1993) Comparisons of dynamic infusions and delayed computed tomography, intraoperative ultrasound and palpation in the diagnosis of liver metastases. Am J Surg 165: 81

    Article  PubMed  CAS  Google Scholar 

  • Kurzgefaßte Interdisziplinäre Leitlinien (2000) Zuckschwerdt, München Bern Wien New York

    Google Scholar 

  • Lai DTM, Fulham M, Stephen MS et al. (1996) The role of whole-body positron emission tomography with [18F] fluorodeoxyglucose in identifying operable colorectal cancer metastases to the liver. Arch Surg 7: 703–706

    Google Scholar 

  • Livraghi T, Vettori C, Lazzaroni S (1991) Liver metastases: Results of percutaneous ethanol injection in 14 patients. Radiology 179: 709–712

    PubMed  CAS  Google Scholar 

  • Livraghi T, Goldberg SN, Monti F et al. (1997) Saline-enhanced radio-frequency tissue ablation in the treatment of liver metastases. Radiology 202: 205–210

    PubMed  CAS  Google Scholar 

  • Lorenz M, Müller HH, Schramm H et al. (1998) Randomized trial of surgery versus surgery followed by adjuvant hepatic arterial infusion with 5-fluorouracil and folinic acid for liver metastases of colorectal cancer. Ann Surg 6: 756–762

    Article  Google Scholar 

  • Machi J, Isomoto H, Yamashita Y, Kurohiji T, Shirouzu K, Kakegawa T (1987) Intraoperative ultrasonography in Screening for liver metastases from colorectal cancer: Comparative accuracy with traditional procedures. Surgery 6: 678–684

    Google Scholar 

  • Majno PE, Adam R, Bismuth H et al. (1997) Influence of preoperative transarterial lipiodol chemoembolization on resection and transplantation for hepatocellular carcinoma in patients with cirrhosis. Ann Surg 6: 688–703

    Article  Google Scholar 

  • Makuuchi M, Hasegawa H, Yamazaki S, Takayasu K, Moriyama N (1987) The use of operative ultrasound as an aid to liver resection in patients with hepatocellular carcinoma. World J Surg 11: 615–621

    Article  PubMed  CAS  Google Scholar 

  • Martin JK Jr, O’Connell MJ, Wieand HS et al. (1990) Intra-arterial floxuridine vs systemic fluorouracil for hepatic metastases from colorectal cancer. A randomized trial. Arch Surg 125: 1022–1027

    Google Scholar 

  • Mazziotti A, Grazi GL, Gardini A et al. (1998) An appraisal of percutaneous treatment of liver metastases. Liver Transplant Surg 4: 271–275

    Article  CAS  Google Scholar 

  • Moran BJ, O’Rourke N, Plant GR, Rees M (1995) Computed tomographic portography in preoperative imaging of hepatic neoplasms. Br J Surg 82: 669

    Article  PubMed  CAS  Google Scholar 

  • Nagorney D, Povoski SP, Fong Y, Sgouros SC, Kemeny NE, Downey RJ, Blumgart LH (1998) Role of ehest CT in patients with negative ehest X-rays referred for hepatic colorectal metastases. Ann Surg Oncol 5: 9–15

    Article  Google Scholar 

  • Nordlinger B, Guiguet M, Vaillant JC, Balladur P, Boudjema P, Bachellier P, Jaeck D (1996) Surgical resection of colorectal carcinoma metastases to the liver. Cancer 7: 1254–1262

    Article  Google Scholar 

  • Olsen AK (1990) Intraoperative ultrasonography and the detection of liver metastases in patients with colorectal cancer. Br J Surg 9: 998–999

    Article  Google Scholar 

  • Pohlen U, Berger G, Binnenhei M, Buhr HJ (1999) Ein neues Konzept zur regionalen Chemotherapie kolorektaler Lebermetastasen. Deutsche Gesellschaft für Chirurgie (Kongressband), S 1286–1288

    Google Scholar 

  • Rafaelsen SR, Kronborg O, Larsen C, Fenger C (1995) Intraoperative ultrasonography in detection of hepatic metastases from colorectal cancer. Dis Colon Rectum 38: 355

    Article  PubMed  CAS  Google Scholar 

  • Rosen CB, Nagorney DM, Taswell HF, Helgeson SL, Ilstrup DM, van Heerden JA, Adson MA (1992) Perioperative blood transfusion and determinants of survival after liver resection for metastatic colorectal carcinoma. Ann Surg 10: 493–505

    Article  Google Scholar 

  • Rossi S, Buscarini E, Garbagnati F et al. (1998) Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR Am J Roentgenol 170: 1015–1022

    PubMed  CAS  Google Scholar 

  • Rougier P, Laplanche A, Huguier M et al. (1992) Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: Long-term results of a prospective randomized trial. J Clin Oncol 10: 1112–1118

    PubMed  CAS  Google Scholar 

  • Scheele J, Stang R, Altendorf-Hofmann A, Paul M (1995) Resection of colorectal liver metastases. World J Surg 19: 59–71

    Article  PubMed  CAS  Google Scholar 

  • Schmidt J, Strotzer M, Fraunhofer St, Boedeker H, Zirngibl H (2000) Intraoperative ultrasonography versus helical computed tomography and computed tomography with arterioportography in diagnosing colorectal liver metastases: Lesion-by-lesion analysis. World J Surg 24: 43–48

    Article  PubMed  CAS  Google Scholar 

  • Scudamore CH, Patterson E, Shapiro AM, Buczkowski AK (1997) Liver tumor ablation techniques. J Invest Surg 10: 157–164

    Article  PubMed  CAS  Google Scholar 

  • Society of American Gastrointestinal Endoscopic Surgeons (1999) Guidelines for diagnostic laparoscopy, SAGES Guidelines. Surg Endosc 13: 202–203

    Article  Google Scholar 

  • Solbiati L, Ierace T, Goldberg SN et al. (1997) Percutaneous US-guided radio-frequency tissue ablation of liver metastases: Treatment and follow-up in 16 patients. Radiology 202: 195–203

    PubMed  CAS  Google Scholar 

  • Soyer P, Levesque M, Elias D, Zeitoun G (1992) Detection of liver metastases from colorectal cancer: Comparison of intraoperative US and CT during arterial portography. Radiology 183: 541–544

    PubMed  CAS  Google Scholar 

  • Soyer P, Bluemke DA, Hruban RH, Sitzmann JV, Fishman EK (1994) Primary malignant neoplasms of the liver: Detection with helical CT during arterial portography. Radiology 192: 389–392

    PubMed  CAS  Google Scholar 

  • Steele G Jr, Bleday R, Mayer RJ, Lindblad A, Petrelli N, Weaver D (1991) A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: Gastrointestinal Tumor Study Group Protocol 6584. J Clin Oncol 7: 1105–1112

    Google Scholar 

  • Sugihara K, Hojo K, Moriya Y, Yamasaki S, Kosuge T, Takayama T (1993) Pattern of recurrence after hepatic resection for colorectal metastases. Br J Surg 8: 1032–1035

    Article  Google Scholar 

  • Takeuchi N, Ramirez JM, Mortensen NJ, Cobb R, Whittlestone T (1996) Intraoperative ultrasonography in the diagnosis of hepatic metastases during surgery for colorectal cancer. Int J Colorectal Dis 11: 92

    PubMed  CAS  Google Scholar 

  • Tellez C, Benson AB III, Lyster MT et al. (1998) Phase II trial of chemoembolisation for the treatment of metastatic colorectal carcinoma of the liver and review of the literature. Cancer 82: 1250–1259

    Article  PubMed  CAS  Google Scholar 

  • Vogl TJ, Mack MG, Straub R, Engelmann K, Zangos S, Eichler K (1999) Interventionelle MR-gesteuerte laserinduzierte Thermotherapie bei onkologischen Fragestellungen. Radiologe 39: 764–771

    Article  PubMed  CAS  Google Scholar 

  • Wagner JS, Adson MA, van Heerden JA, Adson MH, Ilstrup DM (1984) The natural history of hepatic metastases from colorectal cancer. Ann Surg 5: 502–507

    Article  Google Scholar 

  • Wernecke K, Vassallo P, Bick U, Diederich St, Peters PE(1992) The distinction between benign and malignant liver tumors on sonography: Value of a hypoechoic halo. American Roentgen Ray Society 159: 1005–1009

    CAS  Google Scholar 

Download references

Authors
  1. Th. Junginger
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Zentrum der Radiologie, Institut für Diagnostische und Interventionelle Radiologie, Klinikum der J.-W.-Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany

    Thomas J. Vogl , Martin G. Mack  & Jörn O. Balzer ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Junginger, T. (2002). Leitlinien zur Diagnostik und Therapie von Lebermetastasen. In: Vogl, T.J., Mack, M.G., Balzer, J.O. (eds) LeberMetastasen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59385-7_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59385-7_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63958-6

  • Online ISBN: 978-3-642-59385-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation