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Bildgebung der Leberzirrhose und ihrer Komplikationen

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Book cover LeberMetastasen

Zusammenfassung

Die Leberzirrhose ist eine pathologisch-anatomische Diagnose, die mit charakteristischen klinischen Manifestationen einhergeht (Podolsky u. Isselbacher 1987). Histologisch finden sich Leberzellnekrosen neben Hepatozyten mit zytoplasmatischen Fettvakuolen (Steatose). Die von Fibrosesträngen abgegrenzten Regeneratknoten bestehen aus Hepatozyten, Gallengängen und Kupffer-Zellen. Definitionsgemäß unterscheidet man makroskopisch die feinknotige (Knoten <3 mm) von der grobknotigen Leberzirrhose (Knoten >3 mm; Cotran et al. 1989). Ungefähr ein Drittel der Patienten mit Leberzirrhose entwickeln eine sog. konfluierende Fibrose (Dodd et al. 1993), bevorzugt in den Segmenten 4, 5 und 8 (Ohtomo et al. 1993). Im Verlauf der Leberzirrhose kommt es zunächst zur Hepatomegalie, später zur segmentalen Atrophie (typischerweise Segmente 4–8) bzw. Hypertrophie (typischerweise Segmente 1–3; Torres et al. 1986). Abdominelle Lymphknotenvergrößerungen, insbesondere in der Leberpforte, sind bei ca. 65% der Patienten mit Leberzirrhose vorhanden (Orrego et al. 1979).

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Authors
  1. M. Laniado
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Editors and Affiliations

  1. Zentrum der Radiologie, Institut für Diagnostische und Interventionelle Radiologie, Klinikum der J.-W.-Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany

    Thomas J. Vogl , Martin G. Mack  & Jörn O. Balzer ,  & 

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Laniado, M. (2002). Bildgebung der Leberzirrhose und ihrer Komplikationen. In: Vogl, T.J., Mack, M.G., Balzer, J.O. (eds) LeberMetastasen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59385-7_14

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  • DOI: https://doi.org/10.1007/978-3-642-59385-7_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63958-6

  • Online ISBN: 978-3-642-59385-7

  • eBook Packages: Springer Book Archive

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