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Schizophrenie

  • A. Stevens

Zusammenfassung

Die Frage nach einem morphologischen Substrat der schizophrenen Psychose ist alt und wurde immer kontrovers diskutiert. In Deutschland stand die Münchner Schule mit W. Spielmeyer, W. Scholz und G. Peters mit ihrer weitgehenden Ablehnung eines morphologischen Substrats der Schule von O. Vogt gegenüber, die topistische wie zytologische Eigenarten in Gehirnen von Patienten mit schizophrener Psychose erkannte. Seither hat sich nicht nur die Datenerhebung - durch mikroskopisch bzw. makroskopisch quantitative Verfahren -, sondern vor allem die Befundauswertung grundlegend verändert. Während vormals die Zytologie (z.B. der „Schwundzelle“) im Vordergrund stand, geringe Fallzahlen zur Untersuchung kamen und die Ergebnisse narrativ, ohne vergleichende Statistik vorgelegt wurden, spielt die Zytologie heute nur eine geringe Rolle; es dominieren statistisch aufwendige morphometrische Verfahren.

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© Springer-Verlag Berlin Heidelberg 2002

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  • A. Stevens

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