From a Laboratory Tool to a Clinical Application

  • Richard Ben Borgens
Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 171)


All of the studies in rats and guinea pigs noted above, save one, have been conducted using the imposition of DC electrical fields. That is all that is required if one is study­ing the effects of one polarity of voltage applied across axons of one projection, or a behavior (such as the CTM reflex), dependent on spinal cord axons that are of one projection within white matter. While this has been a good way to explore the biolo­gy of applied voltages and nerve regeneration in animals, a clinical tool would not be obvious from such techniques, especially in the injured spinal cord where regenera­tion of both ascending and descending projections are required within the long tracts.

Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Richard Ben Borgens
    • 1
    • 2
  1. 1.School of Veterinary MedicinePurdue UniversityWest LafayetteUSA
  2. 2.School of EngineeringPurdue UniversityWest LafayetteUSA

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