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Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates pp 325–338Cite as

Geography and History of the Genes in the Human MHC: Can We Predict MHC Organization in Nonhuman Primates?

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Abstract

We will provide, in this chapter, an overview of genes that are present in the human MHC and compare the organization of the human and mouse MHC. It will be shown that properties common to the human and mouse MHC correspond to a pleisomorphic, i.e., ancestral, organization. That is, these shared properties are found in all of the ancestors that led up to humans, including primate last common ancestors (belonging to the group Catarrhini).

Quand j’étais enfant, à l’école communale, je n’aimais pas la géographie. PP, Marseille, 5/12/1995

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Authors
  1. R. Tazi Ahnini
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  2. J. Henry
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  3. P. Pontarotti
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Editor information

Editors and Affiliations

  1. Laboratoire d’Immunogénétique moléculaire, Université Paul Sabatier, CHU de Toulouse Hôpital Purpan, Place du Docteur Baylac, 31059, Toulouse cedex, France

    Antoine Blancher MD, PhD

  2. Max-Planck-Institut für Biologie Abteilung Immungenetik, Correnstr. 42, 72076, Tübingen, Germany

    Jan Klein PhD

  3. Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Fl, 33101, USA

    Jan Klein PhD

  4. Laboratory for Experimental Medicine and Surgery in Primates (LEMSIP), New York University Medical Center, 10 Townsend Avenue, Upper Grandview, NY, 10960-4830, USA

    Wladyslaw Socha MD

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© 1997 Springer-Verlag Berlin Heidelberg

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Ahnini, R.T., Henry, J., Pontarotti, P. (1997). Geography and History of the Genes in the Human MHC: Can We Predict MHC Organization in Nonhuman Primates?. In: Blancher, A., Klein, J., Socha, W. (eds) Molecular Biology and Evolution of Blood Group and MHC Antigens in Primates. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59086-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-59086-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63843-5

  • Online ISBN: 978-3-642-59086-3

  • eBook Packages: Springer Book Archive

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