Zusammenfassung
Mit dem Begriff Pubertät bezeichnet man den Lebensabschnitt, in dem sich das Kind zum erwachsenen Menschen entwickelt. Diese Phase der physiologischen Wachstums- und Differenzierungsvorgänge bestimmt das gesamte 2. Lebensjahrzehnt.
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Literatur
Adelman JP, Mason AJ, Hayflick JS, Seeburg PH (1986). Isolation of the gene and hypothalamic cDNA for the common presursor of gonadotropin-releasing hormone and prolactin-release-inhibiting factor in human and rat. Proc Natl Acad Sci USA 83: 179–183
Albertsson-Wikland K, Rosberg S, Lannering B, Dunkel L, Selstam G, Norjavaara E. Twenty-four-hour profiles of luteinizing hormone, follicle-stimulating hormone, testosterone, and estradiol levels: A semilongitudinal study throughout puberty in healthy boys. J Clin Endocrinol Metab 1997; 82: 541–9
Allen LS, Gorski RA (1992) Sexual orientation and the size of the anterior commissure in the human brain. Proc Natl Acad Sci USA 89: 7199–7202
Aloi JA, Dalkin AC, Schwartz NB et al. (1995) Ovarian inhibin subunit gene expression: regulation by gonadotropins and estradiol. Endocrinology 136: 1227–1232
Arslan M, Pohl CR, Plant TM (1988) DL-2-amino-5phosphonopentanoic acid, a specific N-methyl-Daspartic acis receptor antagonist, suppresses pulsatile LH release in the rat. Neuroendocrinology 47: 465–468
Baccetti B, Burrini AG, Capitani S et al. (1993) Studies on varicocele. II. The inhibin secretion. J Submicrosc Cytol Pathol 25: 137–144
Bagatell CJ, Heiman JR, Rivier JE, Bremner WJ (1994) Effects of endogenous testosterone and estradiol on sexual behavior in normal young men. J Clin Endocrinol Metab 78: 711–716
Baien AH, Schachter ME, Montgomery D, Reid RW, Jacobs HS (1993) Polycystic ovaries are a common finding in untreated female to male transsexuals. Clin Endocrinol (Oxf) 38: 325–329
Balthazart J, Ball GF (1995) Sexual differentiation of brain and behavior in birds. Trends Endocrinol Metab 6: 21–29
Balthazart J, Foidart A (1993) Brain aromatase and the control of male sexual behavior. J Steroid Biochem Mol Biol 44: 521–540
Beck W, Wuttke W (1980) Diurnal variations of plasma luteinizing hormone, follicle-stimulating hormone, and prolactin in boys and girls from birth to puberty. J Clin Endocrinol Metab 50: 635–640
Belgorosky A, Chahin S, Chaler E, Maceiras M, Rivarola MA (1996) Serum concentrations of follicle stimulating hormone and luteinizing hormone in normal girls and boys during prepuberty and at early puberty. J Endocrinol Invest 19: 88–91
Bender BG, Harmon RJ, Linden MG, Robinson A (1995) Psychosocial adaptation of 39 adolescents with sex chromosome abnormalities. Pediatrics 96: 302–308
Beyer C, Wozniak A, Hutchison JB (1993) Sex-specific aromatization of testosterone in mouse hypothalamic neurons. Neuroendocrinology 58: 673–681
Biro FM, Lucky AW, Huster GA, Morrison JA (1995) Pubertal staging in boys. J Pediatr 127: 100–102
Black SM, Kaplan SL, Bristow JD, Grumbach MM (1994) Nitric oxide synthesized by GnRH neurons is a mediator of N-methyl-D-aspartate (NMDA)-induced GnRH secretion. Endocrinology 135: 1709–1712
Blos P (1983) Adoleszenz - eine psychoanalytische Interpretation. Klett-Cotta, Stuttgart
Boudou P, Chivot M, Vexiau P et al. (1994) Evidence for decreased androgen 5a-reduction in skin and liver of men with severe acne after 13-cis-retinoic acid treatment. J Clin Endocrinol Metab 78: 1064–1069
Bourguignon J-P (1991) Growth and timing of puberty: reciprocal effects. Horm Res 36: 131–135
Bourguignon J-P (1995) The neuroendocrinology of puberty. Growth Gen Horm 11 (3): 1–6
Bourguignon J-P, Gerard A, Mathieu J, Mathieu A, Franchimont P (1990) Maturation of the hypothalamic control of pulsatile gonadotropin-releasing hormone secretion at onset of puberty. I. Increased activation of N-methyl-D-aspartate receptors. Endocrinology 127: 873–881
Bourguignon J-P, Gerard A, Gonzalez M-LA, Purnelle G, Franchimont P (1995) Endogenous glutamate involvement in pulsatile secretion of gonadotropin-releasing hormone: evidence from effect of glutamine and developmental changes. Endocrinology 136: 911–916
Brennemann W, Klingmüller D, Eter N, Bidlingmaier F (1995) Immunoreactive inhibin concentrations in human gonads and adrenals during the first years of life. Horm Res 44: 115–120
Bridges NA, Hindmarsh PC, Matthews DR, Brook CGD (1994) The effect of changing gonadotropin-releasing hormone pulse frequency on puberty. J Clin Endocrinol Metab 79: 841–847
Bridges NA, Matthews DR, Hindmarsh PC, Brook CGD (1994) Changes in gonadotropin secretion during childhood and puberty. J Endocrinol 141: 169–176
Carley KP, Valk TW, Kelch RP, Marshall JC (1981) Estimation of GnRH pulse amplitude during pubertal development. Pediatr Res 15: 157–160
Chen C-LC (1993) Inhibin and activin as paracrine/ autocrine factors. Endocrinology 132: 4–5
Chowen JA, Busiguina S, Garcia-Segura LM (1995) Sexual dimorphism and sex steroid modulation of glial fibrillary acidic protein messenger RNA and immunoreactivity levels in the rat hypothalamus. Neuroscience 69: 519–532
Clancy AN, Michael RP (1994) Effects of testosterone and aromatase inhibition on estrogen receptor-like immunoreactivity in male rat brain. Neuroendocrinology 59: 552–560
Clancy AN, Zumpe D, Michael RP (1995) Intracerebral infusion of an aromatase inhibitor, sexual behavior and brain estrogen receptor-like immunoreactivity in intact male rats. Neuroendocrinology 61: 98–111
Clayton RN (1989) Gonadotropin-releasing hormone: its actions and receptors. J Endocrinol 120: 11–16
Cohen HN, Hay ID, Annesley TM et al. (1982) Serum immunoreactive melatonin in boys with delayed puberty. Clin Endocrinol (Oxf) 17: 517–521
Cuttler L, Rosenfield RL, Ehrmann DA et al. (1993) Maturation of gonadotropin and sex steroid responses to gonadotropin-releasing hormone agonist in males. J Clin Endocrinol Metab 76: 362–366
Deridder CM, Thijssen JHH, Bruning PF, Van den Brande JL, Zonderland ML, Erich WBM (1992) Body fat mass, body fat distribution, and pubertal development: a longitudinal study of physical and hormonal sexual maturation of girls. J Clin Endocrinol Metab 75: 442–446
Döhler KD, New MI (1989) Sexualentwicklung. In: Hesch RD (Hrsg) Innere Medizin der Gegenwart, Bd Endokrinologie A. Urban & Schwarzenberg, München, S 501–512
Dunkel L, Alfthan H, Stenman U-H, Tapanainen P, Perheentupa J (1990) Pulsatile secretion of LH and FSH in prepubertal and early pubertal boys revealed by ultrasensitive time resolving immunofluorometric assays. Pediatr Res 27: 215–219
El-Migdadi F, Gallant S, Brownie AC (1995) Sex differences in cytochromes oxidase and P 45011 in the rat adrenal cortex. Mol Cell Endocrinol 112: 185–194
El-Migdadi F, Gallant S, Brownie AC (1995) Sex differences in the steroidogenic and respiratory electron transport chains in the rat adrenal cortex. Endocr Res 21: 109–114
Emans SJ, Woods ER, Allred EN, Grace E (1994) Hymenal findings in adolescent women: impact of tampon use and consensual sexual activity. J Pediatr 125: 153–160
Erickson GF, McLachlan RI, McClure N, Healy DL, Burger HG (1995) The ovary: basic principles and concepts; A. Physiology, B. Clinical. In: Felig P, Baxter JD, Frohman LA (eds) Endocrinology and metabolism. McGraw-Hill, New York London Milan Toronto Tokyo Sydney, pp 973–1052
Fiddes JC, Talmadge K (1984) Structure, expression, and evolution of the genes for human glycoprotein hormones. Rec Progr Horm Res 40: 43–78
Findlay JK (1993) An update on the roles of inhibin, activin, and follistatin as local regulators of folliculoge-nesis. Biol Reprod 48: 15–23
Forest MG (1990) Pituitary gonadotropin and sex steroid secretion during the first two years of life. In: Grumbach MM, Sizonenko PC, Aubert ML (eds) Con-trol of the onset of puberty. Williams & Wilkins, Baltimore, pp 451–478
Genazzani AR, Palumbo MA, De Micheroux AA et al. (1995) Evidence for a role for the neurosteroid allopregnanolone in the modulation of reproductive function in female rats. Eur J Endocrinol 133: 375–380
Ghai K, Rosenfield RL (1994) Maturation of the normalpituitary-testicular axis, as assessed by gonadotropinreleasing hormone agonist challenge. J Clin Endocrinol Metab 78: 1336–1340
Giusti M, Falivene MR, Carraro A, Cuttica CM, Valenti S, Giordano G (1995) The effect of non-steroidal anti-androgen flutamide on luteinizing hormone pulsatile secretion in male-to-female transsexual subjects. JEndocrinol Invest 18: 420–426
Godwin J, Crews D (1995) Sex differences in estrogen and progesterone receptor messenger ribonucleic acid regulation in the brain of little striped whiptail lizards. Neuroendocrinology 62 293–300
Goji K, Tanikaze S (1993) Spontaneous gonadotropin and testosterone concentration profiles in prepubertal63. and pubertal boys: temporal relationship between luteinizing hormone and testosterone. Pediatr Res 34: 229–236
Gorski RA (1993) Estradiol acts via the estrogen recep-tor in the sexual differentiation of the rat brain, but what does this complex do. Endocrinology 133: 431–432
Grumbach MM, Kaplan SL (1990) The neuroendocrinology of human puberty: an ontogenetic perspective. In:z 65. Grumbach MM, Sizonenko PC, Aubert ML (eds) Control of the onset of puberty. Williams & Wilkins, Baltimore, pp 1–68
Grumbach MM, Styne DM (1992) Puberty: ontogeny, neuroendocrinology, physiology, and disorders. In: Wilson JD, Foster DW (eds) Williams textbook of endocrinology. WB Saunders, Philadelphia London Toronto, pp 1139–1221
Gunasegaram R, Loganath A, Peh KL, Ratnam SS (1995) Aromatization of [4–14C]testosterone to [14C]estradiol- 170 by testicular tissue from male-to-female transsexuals on estrogen therapy. Arch Androl 35: 127–133
Hamer DH, Hu S, Magnuson V, Hu N, Pattatucci AML (1993) Male sexual orientation and genetic evidence. Science 262: 2063–2065
Hammond GL, Bocchinfuso WP (1996) Sex hormone-binding globulin: gene organization and structure fun-ction analyses. Horm Res 45: 197–201
Hardelin JP, Levilliers J, Young J et al. (1993) Xp 22.3 deletions in isolated familial Kallmann’s syndrome. J Clin Endocrinol Metab 76: 827–831
Healy E, Simpson N (1994) Fortnightly review: Acne vulgaris. BMJ 308: 831–833
.Hee JP, MacNaughton J, Bangah M et al. (1993) Follicle-stimulating hormone induces dose-dependant stimulation of immunoreactive inhibin secretion during the follicular phase of the human menstrual cycle. J Clin Endocrinol Metab 76: 1340–1343
Hu S-B, Nowak FV (1995) Sex-specific changes in pre-optic regulatory factor-1 and preoptic regulatory factor-2 mRNA expression in the rat brain during development. Endocrine 3: 421–424
Hu S, Pattatucci AML, Patterson C et al. (1995) Linkage between sexual orientation and chromosome Xq28 in males but not in females. Nature Genet 11: 248–256
Jackacki RI, Kelch RP, Sauder SE, Lloyd JS, Hopwood NJ, Marshall JC (1982) Pulsatile secretion of luteinizing hormone in children. J Clin Endocrinol Metab 55: 453–458
Juarez J, Corsi-Cabrera M, Del Río-Portilla I (1995) Effects of prenatal testosterone treatment on sex differences in the EEG activity of the rat. Brain Res 694: 21–28
Kletter GB, Padmanabhan V, Brown MB, Reiter EO, Sizonenko PC, Beitins IZ (1993) Serum bioactive gonadotropins during male puberty: a longitudinal study. J Clin Endocrinol Metab 76: 432–438
Krummen LA, Woodruff TK, DeGuzman G et al. (1993) Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids. Endocrinology 132: 431–443
: Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ (1994) Sex differences in the development of estrogen receptors in the rat brain. Horm Behav 28: 483–491
Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ (1995) Sexual differentiation of estrogen receptor concentrations in the rat brain: effects of neonatal testosterone exposure. Brain Res 691: 229–234
Kuhnle U, Bullinger M, Schwarz HP, Knorr D (1993) Partnership and sexuality in adult female patients with congenital adrenal hyperplasia. First results of a cross-sectional quality-of-life evaluation. J Steroid Biochem Mol Biol 45: 123–126
Kuhn HE, Grumbach MM, Kaplan SL (1969) Changing sensivity of pubertal gonadal hypothalamic feedback mechanism in man. Science 166: 1012–1018
Kuljis RO, Advis JP (1989) Immunocytochemical and physiological evidence of a synapse between dopamine-and luteinizing hormone releasing hormone-containing neurons in the ewe median eminence. Endocrinology 124: 1579–1581
Labhard A (1986) Clinical Endocrinology. Theory and praxis. Springer, Berlin Heidelberg New York
Largo RH, Prader A (1983) Pubertal development in Swiss boys. Helv Paediatr Acta 38: 211–228
Largo RH, Prader A (1983) Pubertal development in Swiss girls. Helv Paediatr Acta 38: 229–243
Largo RH, Prader A (1987) Somatische Pubertätsentwicklung bei Mädchen. Monatschr Kinderheilkd 135: 479–484
Leranth C, MacLusky NJ, Sakamoto H et al. (1985) Glu-tamic acid decarboxylase-containing axons synapse on LHRH-neurons in the rat medial preoptic area. Neuro-endocrinology 40: 536–539
Lisciotto CA, Morrell JI (1994) Sex differences in the distribution and projections of testosterone target neurons in the medial preoptic area and the bed nucleus of the stria terminalis of rats. Horm Behav 28: 492–502
Lucky AW (1995) Hormonal correlates of acne and hirsutism. Am J Med 98 (Suppl) 1A: 89S–94S
Mahachoklertwattana P, Sanchez J, Kaplan SL, Grumbach MM (1994) N-methyl-D-aspartate (NMDA) receptors mediate the release of gonadotropin-releasing hormone (GnRH) by NMDA in a hypothalamic GnRH neuronal cell line (GT1–1). Endocrinology 134: 1023–1030
Malhotra A, Poon E, Tse W-Y, Pringle PJ, Hindmarsh PC, Brook CGD (1993) The effects of oxandrolone on the growth hormone and gonadal axes in boys with constitutional delay of growth and puberty. Clin Endocrinol (Oxf) 38: 393–398
Manasco PK, Umbach DM, Muly SM et al. (1995) Ontogeny of gonadotropin, testosterone, and inhibin secretion in normal boys through puberty based on overnight serial sampling. J Clin Endocrinol Metab 80: 2046–2052
Maszak G, Becker K, Conway S (1995) The development of sexually dimorphic sensitivity to growth hormone (GH) feedback of the clonidine-induced GH surge in the rat. Neuroendocrinology 62: 301–307
Matuszczyk JV, Larsson K (1995) Sexual preference and feminine and masculine sexual behavior of male rats prenatally exposed to antiandrogen or antiestrogen. Horm Behav 29: 191–206
Mauras N, Veldhuis JD, Rogol AD (1986) Role of endogenous opiates in pubertal maturation: opposing actions of naltrexone in prepubertal and late pubertal boys. J Clin Endocrinol Metab 62: 1256–1263
Mauras N, Rogol AD, Haymond MW, Veldhuis JD (1996) Sex steroids, growth hormone, insulin-like growth factor-1: neuroendocrine and metabolic regulation in puberty. Horm Res 45: 74–80
Mayo KE (1994) Inhibin and activin: molecular aspects of regulation and function. Trends Endocrinol Metab 5: 407–415
McCormick CM, Smythe JW, Beers D (1994) Sex differences in type I corticosteroid receptor binding in selective brain areas of rats. Ann NY Acad Sci 746: 431–433
Metzger DL, Kerrigan JR, Rogol AD (1994) Gonadal steroid hormone regulation of the somatotropic axis during puberty in humans: mechanisms of androgen and estrogen action. Trends Endocrinol Metab 5: 290–296
Möcks P, Schmidt MH (1990) Die regelhafte Pubertät - psychologische and psychosoziale Aspekte. In: Burmeister W, Heimann G, Sitzmann FC (Hrsg) Jugendmedizin - Band 94 Bücherei des Pädiaters. Enke, Stuttgart, pp 11–21
Montano MM, Welshons WV, Vom Saal FS (1995) Free estradiol in serum and brain uptake of estradiol during fetal and neonatal sexual differentiation in female rats. Biol Reprod 53: 1198–1207
Moodbidri SB, Garde SV, Sheth AR (1992) Inhibin: unity in diversity. Arch Androl 28: 149–157
Panzica GC, Aste N, Viglietti-Panzica C, Ottinger MA (1995) Structural sex differences in the brain: influence of gonadal steroids and behavioral correlates. J Endocrinol Invest 18: 232–252
Pattatucci AML, Hamer DH (1995) Development and familiality of sexual orientation in females. Behav Genet 25: 407–420
Penny R, Olambiwonu NO, Frasier SD (1977) Episodic fluctuations of serum gonadotropins in pre-and postpubertal girls and boys. J Clin Endocrinol Metab 45: 307–312
Perheentupa A, Bergendahl M, De Jong FH, Huhtaniemi I (1993) Differential regulation of FSH and inhibin gene expression and synthesis by testosterone in immature and mature male rats. J Endocrinol 137: 69–79
Plant TM (1988) Puberty in primates. In: Knobil E, Neill JD (eds) The physiology of reproduction. Raven, New York, pp 1763–1788
Plant TM, Gay VL, Marshall GR et al. (1989) Puberty in monkeys is triggered by chemical stimulation of the hypothalamus. Proc Natl Acad Sci USA 86: 2506–2510
Plymate SR, Paulsen CA, McLachlan RI (1992) Relationship of serum inhibin levels to serum follicle stimulating hormone and sperm production in normal men and men with varicoceles. J Clin Endocrinol Metab 74: 859–864
Pool R (1993) Evidence for homosexuality gene. Science 261: 291–292
Prader A, Largo RH, Wolf C (1984) Timing of pubertal growth and maturation in the first Zurich longitudinal growth study. Acta Paediatr Hung 25: 155–159
Prader A, Largo RH, Molinari L, Issler C (1989) Physical growth of Swiss children from birth to 20 years of age - first Zurich longitudinal study of growth and development. Helv Paediatr Acta (Suppl) 52: 1–125
Reite M, Sheeder J, Teale P, Richardson D, Adams M, Simon J (1995) Meg based brain laterality: sex differences in normal adults. Neuropsychologia 33: 1607–1613
Reiter RJ (1980) The pineal and its hormones in the control of reproduction in mammals. Endocr Rev 1:109–131
Relkin R (1983) The pineal gland. In: Relkin R (ed) Current endocrinology. Elsevier, New York, pp 121–163
Roberts VJ, Peto CA, Vale W, Sawchenko PE (1992) Inhibin/activin subunits are costored with FSH and LH in secretory granules of the rat anterior pituitary gland. Neuroendocrinology 56: 214–224
Robertson DM, Sullivan J, Watson M, Cahir N (1995) Inhibin forms in human plasma. J Endocrinol 144: 261–269
Roelfsema F, Van den Berg G, Frölich M et al. (1993) Sex-dependent alteration in cortisol response to endogenous adrenocorticotropin. J Clin Endocrinol Metab 77: 234–240
Roselli CE, Resko JA (1993) Aromatase activity in the rat brain: hormonal regulation and sex differences. J Steroid Biochem Mol Biol 44: 499–508
Ruf KB (1973) How does the brain control the process of puberty? J Neurol 204: 95–101
Santen RJ (1995) The testis. In: Felig P, Baxter JD, Froh-man LA (eds) Endocrinology and metabolism. McGraw-Hill, New York London Milan Tokyo Sydney Toronto, pp 885–972
Schwanzel-Fuduka M, Bick MD, Pfaff DW (1989) Luteinizing hormone-releasing hormone (LHRH)- expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome. Mol Brain Res 6: 311–326
Sholl SA, Goy RW, Kim KL (1989) 5-alpha-reductase, aromatase, and androgen receptor levels in the monkey brain during fetal development. Endocrinology 124: 627–634
Spiteri-Grech J, Nieschlag E (1992) The role of growth hormone and insulin-like growth factor I in the regulation of male reproductive function. Horm Res 38 (Suppl 1):22–27
Stolecke H (1987) Klinische und endokrinologische Merkmale der weiblichen Pubertät. In: Stolecke H, Terruhn V (Hrsg) Pädiatrische Gynäkologie. Springer, Berlin Heidelberg New York, S 83–103
Stolecke H (1990) Spezielle klinische Probleme - Abschn. 3.1: Akne. In: Burmeister W, Heimann G, Sitzmann FC (Hrsg) Jugendmedizin; Bd 94 Bücherei des Pädiaters. Enke, Stuttgart, S 26–27
Stolecke H (1990) Die regelhafte Pubertät, Abschn. 1.2: Klinischer Ablauf der Reifeentwicklung. In: Burmeister W, Heimann C, Sitzmann FC (Hrsg) Jugendmedizin; Bd 94 Bücherei des Pädiaters. Enke, Stuttgart, S 1–21
Stolecke H, Terruhn V (Hrsg) (1987) Pädiatrische Gynäkologie. Springer, Berlin Heidelberg New York
Stolecke H (1997) Progression der geschlechtsspezifischen Entwicklung. In: Ranke MB, Stolecke H: Pubertätsentwicklung. Dokument + Bild, Ankum-Kettenkamp, p. 19–35
Tanner JM (1973) Trend toward earlier menarche in London, Oslo, Copenhagen, The Netherlands and Hungary. Nature 243: 95–97
Tanner JM, Eveleth PB (1975) Changes at age in menarche in Scandinavian countries, 1840–1978. In: Berenberg SR (ed) Puberty, biologic and psychosocial components. HE Stenfert Krose, Leiden, pp 256
Thind KK, Goldsmith PC (1988) Infundibular gonadotropin releasing hormone neurons are inhibited by direct opioid and autoregulatory synapses in juvenile monkeys. Neuroendocrinology 47: 203–216
Thorner MO, Vance ML, Horvath E, Kovacs K (1992) The anterior pituitary. In: Wilson JD, Foster DW (eds) Williams textbook of endocrinology. WB Saunders, Philadelphia London Toronto Sydney Tokyo, pp 221–310
Tilbrook AJ, De Kretser DM, Clarke IJ (1993) Human recombinant inhibin A and testosterone act directly at the pituitary to suppress plasma concentrations of FSH in castrated rams. J Endocrinol 138: 181–189
Travers SH, Jeffers BW, Bloch CA, Hill JO, Eckel RH (1995) Gender and Tanner stage differences in body composition and insulin sensitivity in early pubertal children. J Clin Endocrinol Metab 80: 172–178
VanFurth WR, Wolterink G, Van Ree JM (1995) Regulation of masculine sexual behavior: involvement of brain opioids and dopamine. Brain Res Rev 21: 162–184
VanWayjen RGA, Van den Ende A (1995) Experience in the long-term treatment of patients with hirsutism and/ or acne with cyproterone acetate-containing preparations: efficacy, metabolic and endocrine effects. Exp Clin Endocrinol Diabetes 103: 241–251
Vaughan GM, Meyer GG, Reiter RJ (1978) Evidence for a pineal-gonadal relationship. In: Reiter RJ (ed) The pineal and reproduction. Karger, Basel, pp 191–233
Vieira JGH, Nishida SK, Pereira AB, Arraes RF, Verreschi ITN (1994) Serum levels of prostate-specific antigen in normal boys throughout puberty. J Clin Endocrinol Metab 78: 1185–1187
Warkins PC, Eddy R, Beck AK et al. (1987) DNA sequence and regional assignment of the human follicle-stimulating hormone 3-subunit gene to the short arm of human chromosome 11. DNAcid 6: 205–212
Weissberger AJ, Ho KKY (1993) Activation of the somatotropic axis by testosterone in adult males: evidence for the role of aromatization. J Clin Endocrinol Metab 76: 1407–1412
Wu FCW, Brown DC, Butler GE, Stirling HF, Kelnar CJH (1993) Early morning plasma testosterone is an accurate predictor of imminent pubertal development in prepubertal boys. J Clin Endocrinol Metab 76: 26–31
Yahr P, Greene SB (1992) Effects of unilateral hypothalamic manipulations on the sexual behaviors of rats. Behav Neurosci 106: 698–709
Zacharias LM, Rand M, Wurtman R (1976) A prospective study of sexual development in American girls: the statistics of menarche. Obstet Gynecol Sury 31: 325–337
Zhou JN, Hofman MA, Gooren LJG, Swaab DF (1995) A sex difference in the human brain and its relation to transsexuality. Nature 378: 68–70
Ziegler NI von, Lichtensteiger W (1992) Asymmetry of brain aromatase activity: region-and sex-specific developmental patterns. Neuroendocrinology 55: 512–518
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Stolecke, H. (1997). Physiologie und klinischer Ablauf der Pubertät. In: Stolecke, H. (eds) Endokrinologie des Kindes- und Jugendalters. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59043-6_14
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