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Hormonregulation des Salz- und Wasserhaushalts

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Endokrinologie des Kindes- und Jugendalters

Zusammenfassung

Die neuroendokrine Regulation des Salz- und Wasserhaushalts ist Teil eines sehr komplexen Systems, das den arteriellen Blutdruck und die Konstanz des „inneren Milieus“ (Osmolalität der Körperflüssigkeiten, Natriumbestand des Extrazellularraums) reguliert. Die endokrine Regulation ist daher nur in Kenntnis der engen Verknüpfung von Volumen- und Kreislaufregulation über neuroendokrine Systeme und deren Wirkung auf die Zielorgane, wie z. B. Herz, Kreislauf und Nieren, zu interpretieren.

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Literatur

  1. Aronson AS, Svenningsen NW (1974) DDAVP test for estimation of renal concentrating capacity in infants and children. Arch Dis Child 49: 654–659

    Article  PubMed  CAS  Google Scholar 

  2. Aynsley-Green A, Pickering D (1974) Use of central and peripheral temperature measurement in care of the critically ill child. Arch Dis Child 49: 477–481

    Article  PubMed  CAS  Google Scholar 

  3. Ayus JC, Krothapalli RK, Arieff AI (1987) Treatment of symptomatic hyponatremia and its relation to brain damage. N Engl J Med 317: 1190–1195

    Article  PubMed  CAS  Google Scholar 

  4. Berry PL, Belsha CW (1990) Hyponatremia. Pediatr Clin North Am 37: 351–363

    CAS  Google Scholar 

  5. Birnbaumer M, Seibold A, Gilbert S et al. (1992) Molecular cloning of the receptor for human antidiuretic hormone. Nature 357: 333–335

    Article  PubMed  CAS  Google Scholar 

  6. Conley SB (1990) Hypernatremia. Pediatr Clin North Am 37: 365–372

    CAS  Google Scholar 

  7. Cowley AW (1982) Vasopressin in cardiovascular regulation. In: Guyton AC, Hall JE (eds) Cardiovascular physiology IV, International Review of Physiology, vol 26. University Park Press, Baltimore, pp 189–242

    Google Scholar 

  8. Cowley AM, Switzer SJ, Guinn MM (1980) Evidence and quantification of the vasopressin arterial pressure control system in the dog. Circ Res 46: 58–67

    PubMed  CAS  Google Scholar 

  9. Daniel SS, Stark RI, Husain MK, Sanocka UM, James LS (1984) Excretion of vasopressin in the hypoxic lamb: comparison between fetus and newborn. Pediatr Res 18: 227–231

    Article  PubMed  CAS  Google Scholar 

  10. Deen PMT, Verdijk MAJ, Knoers NVAM et al. (1994) Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine. Science 264: 92–95

    Article  PubMed  CAS  Google Scholar 

  11. De Robertis FR, Michelis MF, Davis BB (1974) „Essential“ hypernatremia: report of three cases and review of the literature. Arch Intern Med 134: 889–895

    Article  Google Scholar 

  12. De Vane GW, Porter JC (1980) An apparent stress-induced release of arginine vasopressin by human neonates. J Clin Endocrinol Metab 51: 1412–1416

    Article  Google Scholar 

  13. De Vane GW, Naden RP, Porter JC, Rosenfeld CR (1982) Mechanism of arginine-vasopressin release in the sheep fetus. Pediatr Res 16: 504–507

    Google Scholar 

  14. Feigin RD, McCracken GH, Klein JO (1992) Diagnosis and managemant of meningitis. Pediatr Infect Dis J 11: 785–814

    Article  PubMed  CAS  Google Scholar 

  15. Fujiwara TM, Morgan K, Bichet DG (1995) Molecular biology of diabetes insipidus. Ann Rev Med 46: 331–343

    Article  PubMed  CAS  Google Scholar 

  16. Gerigk M, Bald M, Feth F, Rascher W (1993) Clinical settings and vasopressin function in hyponatremia. Eur J Pediatr 152: 301–305

    Article  PubMed  CAS  Google Scholar 

  17. Gerigk M, Glanzmann R, Rascher W, Gnehm HE (1995) Hyponatremia and hyperkalemia in acute pyelonephritis without urinary tract anomalies. Eur J Pediatr 154: 582–584

    Article  PubMed  CAS  Google Scholar 

  18. Gerigk M, Gnehm HPE, Rascher W (1996) Arginine vasopressin and renin in acutely ill children: implication for fluid therapy. Acta Paediatr 85 (in press)

    Google Scholar 

  19. Gomez-Sanchez EP, Foecking MF, Sellers D, Blankenship MS, Gomez-Sanchez CE (1994) Is the circulating ouabainlike compound ouabain? Am J Hypertens 7: 647–650

    PubMed  CAS  Google Scholar 

  20. Gozal D, Colin AA, Jaffe M, Hochberg Z (1990) Water, electrolyte and endocrine homeostasis in infants with bronchiolitis. Pediatr Res 27: 204–209

    Article  PubMed  CAS  Google Scholar 

  21. Hadeed AJ, Leake RD, Weitzmann RE, Fisher DA (1979) Possible mechanisms of high blood levels of vasopressin during neonatal period. J Pediatr 94: 805–808

    Article  PubMed  CAS  Google Scholar 

  22. Hamlyn JM, Manunta P (1992) Ouabain, digitalis-like factor and hypertension. J Hypertens 10 (Suppl7): 99–111

    Google Scholar 

  23. Hammond DN, Moll GW, Robertson GL, Chelmicka-Schorr E (1986) Hypodipsic hypernatremia with normal osmoregulation of vasopressin. N Engl J Med 315: 433–436

    Article  PubMed  CAS  Google Scholar 

  24. Haycock GB (1995) The syndrome of inappropriate secretion of antidiuretic hormone. Pediatr Nephrol 9: 375–381

    Article  PubMed  CAS  Google Scholar 

  25. Hazinski TA, Blalock WA, Engelhardt B (1988) Control of Water balance in infants with bronchopulmonary dysplasia: role of endogenous vasopressin. Pediatr Res 23: 86–88

    Article  PubMed  CAS  Google Scholar 

  26. van der Heijden AJ, Versteeg FGA, Wolff EO, Sukhai RN, Scholtmeijer RJ (1985) Acute tubular dysfunction in infants with obstructive uropathy. Acta Paediatr Scand 74: 589–594

    Article  Google Scholar 

  27. Hirasawa A, Shibata K, Kotosai K, Tsujimoto G (1994) Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor. Biochem Biopys Res Commun 203:72–79

    Article  CAS  Google Scholar 

  28. Judd BA, Haycock GB, Dalton N, Chantler C (1987) Hyponatremia in premature babies and following surgery in older children. Acta Paediatr Scand 76: 385–393

    Article  PubMed  CAS  Google Scholar 

  29. Judd BA, Haycock GB, Dalton RN, Chantler C (1990) Antidiuretic hormone following surgery in children. Acta Paediatr Scand 79: 461–466

    Article  PubMed  CAS  Google Scholar 

  30. Kojima T, Fukuda Y, Hirata Y, Matsuzaki S, Kobayashi Y (1990) Changes in vasopressin, atrial natriuretic factor and water homeostasis in the early stage of bronchopulmonary dysplasia. Pediatr Res 27: 260–263

    Article  PubMed  CAS  Google Scholar 

  31. Land H, Schütz G, Schmale H, Richter D (1982) Nucleotide sequence of cloned cDNA encoding bovine argini-ne vasopressin-neurophysin II precursor. Nature 295: 299–303

    Article  PubMed  CAS  Google Scholar 

  32. Lewis LK, Yandle TG, Lewis JG, Richards AM, Pidgeon GB, Kaaja RJ, Nicholls G (1994) Ouabain is not detectable in human plasma. Hypertension 24: 549–555

    PubMed  CAS  Google Scholar 

  33. van Lieburg AF, Verdijk MAJ, Knoers NVAM et al. (1994) Patients with autosomal nephrogenic diabetes insipidus: homozygous for mutations in the aquaporin 2 water channel gene. Am J Human Genet 55: 648–652

    Google Scholar 

  34. Melzi ML, Guez S, Sersale G et al. (1995) Acute pyelonephritis as a cause of hyponatremia/hyperkalemia in young infants with urinary tract malformations. Pediatr Infect Dis J 14: 56–59

    Article  PubMed  CAS  Google Scholar 

  35. Möhring J, Glänzer K, Maciel JA Jr, Düsing R, Kramer HJ, Arbogast R, Koch-Weser J (1980) Greatly enhanced pressor response to antidiuretic hormone in patients with impaired cardiovascular reflexes due to idiopathic orthostatic hypotension. J Cardiovasc Pharmacol 2: 367–376

    Article  PubMed  Google Scholar 

  36. Pohjavuori M, Fyhrquist F (1980) Hemodynamic significance of vasopressin in the newborn infant. J Pediatr 97: 462–465

    Article  PubMed  CAS  Google Scholar 

  37. Powell KR, Sugarman LI, Eskenazi AE et al. (1990) Normalization of plasma arginine vasopressin concentrations when children with meningitis are given maintenance plus replacement therapy. J Pediatr 117: 515–522

    Article  PubMed  CAS  Google Scholar 

  38. Quillen EW, Cowley AM (1983) Influence of volume changes on osmolality-vasopressin relationship in conscious dogs. Am J Physiol 244: H73–H79

    PubMed  CAS  Google Scholar 

  39. Rao M, Eid M, Herrod L, Parekh A, Steiner P (1986) Antidiuretic hormone response in children with bronchopulmonary dysplasia during episodes of acute respiratory distress. Am J Dis Child 140: 825–828

    PubMed  CAS  Google Scholar 

  40. Rascher W (1985) Kardiovaskuläre Wirkung des antidiuretischen Hormons Arginin-Vasopressin. Klin Wochenschr 63: 989–999

    Article  PubMed  CAS  Google Scholar 

  41. Rascher W (1993) Blutdruck-and Volumenregulation beim nephrotischen Syndrom. Nieren-and Hochdruckkrankheiten 22: 435–439

    Google Scholar 

  42. Rascher W, Tulassay T (1987) Hormonal regulation of water metabolism in children with nephrotic syndrome. Kidney Intern 32 (Suppl 21): S83–S89

    Google Scholar 

  43. Rascher W, Meffle H, Gross F (1985) Hemodynamic effects of arginine vasopressin in conscious water-deprived rats. Am J Physiol 249: H29–H33

    PubMed  CAS  Google Scholar 

  44. Rascher W, Tulassay T, Lang RE (1985) Atrial natriuretic peptide in plasma of volume-overloaded children with chronic renal failure. Lancet 2: 303–305

    Article  PubMed  CAS  Google Scholar 

  45. Rascher W, Rosendahl W, Henrichs JA, Maier R, Seyberth HW (1987) Congenital nephrogenic diabetes insipidus - vasopressin and prostaglandin in response to treatment with hydrochlorothiazid and indomethacin. Pediatr Nephrol 1: 485–490

    Article  PubMed  CAS  Google Scholar 

  46. Rascher W, Rauh W, Brandeis WE, Huber KH, Schärer K (1986) Determinants of plasma arginine-vasopressin in children. Acta Paediatr Scand 75: 111–117

    Article  PubMed  CAS  Google Scholar 

  47. Rascher W, Bello AB, Lettgen B, Guth-Tougelidis B, Müller ST, Reiners Chr, Löhr E (1990) Diagnostische Bedeutung der Captopril-Radionuklidnephrographie für die renovaskuläre Hypertonie im Kindesalter. Monatsschr Kinderheilkd 138: 268–273

    PubMed  CAS  Google Scholar 

  48. Rees L, Forsling ML, Brook CGD (1980) Vasopressin concentration in the neonatal period. Clin Endocrinol 12: 357–362

    Article  CAS  Google Scholar 

  49. Robertson GL (1984) Abnormalities of thirst regulation. Kidney Int 25: 460–469

    Article  PubMed  CAS  Google Scholar 

  50. Rosenthal W, Seibold A, Antaramian A et al. (1992) Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus. Nature 359: 233–235

    Article  PubMed  CAS  Google Scholar 

  51. Rowe JW, Shelton RL, Helderman JH, Vestal RE, Robertson GL (1979) Influence of the emetic reflex on vasopressin release in man. Kidney Int 16: 729–735

    Article  PubMed  CAS  Google Scholar 

  52. Ruskoaho H (1992) Atrial natriuretic peptide: synthesis, release and metabolism. Pharmacol Rev 44: 479–602

    PubMed  CAS  Google Scholar 

  53. Samani NJ, Swales JD (1991) Molecular biology of the vascular renin angiotensin system. Blood Vessels 28: 210–216

    PubMed  CAS  Google Scholar 

  54. Schaff-Blass E, Robertson GL, Rosenfield RL (1983) Chronic hypernatremia resulting from a congenital defect in osmoregulation of thirst and vasopressin. J Pediatr 102: 703–708

    Article  PubMed  CAS  Google Scholar 

  55. Schrier RW (1985) Treatment of hyponatremia. N Engl J Med 312: 1121–1123

    Article  PubMed  CAS  Google Scholar 

  56. Schrier RW (1988) Pathogenesis of sodium and water retention in high-output and low-output cardiac failure, nephrotic syndrome, cirrhosis and pregnancy. N Engl J Med 319: 1065–1072 and 1127–1134

    Article  PubMed  CAS  Google Scholar 

  57. Schrier RW, Berl T, Anderson RJ (1979) Osmotic and non-osmotic control of vasopressin release. Am J Physiol 236: F321–F332

    PubMed  CAS  Google Scholar 

  58. Singhi SC, Singhi PD, Srinivas B, Narakesri HP, Ganguli NK, Sialy R, Walia BNS (1995) Fluid restriction does not improve the outcome os acute meningitis. Pediatr Infect Dis J 14: 495–503

    Article  PubMed  CAS  Google Scholar 

  59. Skorecki KL, Brenner BM (1981) Body fluid homeostasis in man. Am J Med 70: 77–88

    Article  PubMed  CAS  Google Scholar 

  60. Speer ME, Gorman WA, Kaplan SL, Rudolph AJ (1984) Elevation of plasma concentration of arginine vasopressin following perinatal asphyxia. Acta Paediatr Scand 73: 610–614

    Article  PubMed  CAS  Google Scholar 

  61. Thibonnier M, Auzan C, Madhun Z, Wilkins P, Berti-Mattera L, Clauser E (1994) Molecular cloning, sequencing, and functional expression of a cDNA encoding the human VI vasopressin receptor. J Biol Chem 269: 3304–3310

    PubMed  CAS  Google Scholar 

  62. Timmermans PBMW, Wong PC, Chiu AT et al. (1993) Angiotensin II receptors and angotensin II receptor antagonists. Pharmacol Rev 45: 205–251

    PubMed  CAS  Google Scholar 

  63. Tulassay T, Rascher W (1986) Atriales natriuretisches Peptid. Monatsschr Kinderheilkd 134: 710–715

    PubMed  CAS  Google Scholar 

  64. Tulassay T, Seri I, Rascher W (1987) Atrial natriuretic peptide and extracellular volume contraction after birth. Acta Pediatr Scand 76: 444–446

    Article  CAS  Google Scholar 

  65. Tulassay T, Rascher W, Lang RE, Seyberth HW, Schärer K (1987) Atrial natriuretic peptide and other vasoactive hormones in nephrotic syndrome. Kidney Int 31: 1391–1395

    Article  PubMed  CAS  Google Scholar 

  66. Tulassay T, Ruskoaho H, Toth M, Rascher W (1988) Atrial natriuretic peptid in volume expansion-induced natriuresis in man. Clin Exp Hypertens A10: 363–380

    Article  CAS  Google Scholar 

  67. Waeber B, Nussberger J, Hofbauer KG, Nicod P, Brunner H (1986) Clinical studies with a vascular vasopressin antagonist. J Cardiovasc Pharmaco l8 (Suppl 7): S1115116

    Google Scholar 

  68. Weitzmann RE, Reviczky A, Oddie TH, Fisher DA (1980) Effect of osmolality on arginine vasopressin and renin release after hemorrhage. Am J Physiol 238: E62–E68

    Google Scholar 

  69. Woolfson RG, Poston L, DeWardener HE (1994) Digoxinlike inhibitor of active sodium transport and blood pressure: the current status. Kidney Intern 46: 297–309

    Article  CAS  Google Scholar 

  70. Worgall S, Hänze J, Wagner R, Peiser C, Lang RE, Sulyok E, Rascher W (1996) Characterization of ouabain-like immunoreactivity in human urine. J Hypertens 14: 623–628

    Article  PubMed  CAS  Google Scholar 

  71. Young DB, Pan YJ, Guyton AC (1977) Control of extracellular sodium concentration by antidiuretic hormone-thirst feedback mechanism. Am J Physiol 232: R145–R149

    PubMed  CAS  Google Scholar 

  72. Zerbe RL, Robertson GL (1981) A comparison of plasma measurements with a standard indirect test in the differential diagnosis of polyuria. N Engl J Med 305: 1539–1546

    Article  PubMed  CAS  Google Scholar 

  73. Zerbe RL, Robertson GL (1983) Osmoregulation of thirst and vasopressin secretion in human subjects: effects of various solutes. Am J Physiol 244: E607–E614

    PubMed  CAS  Google Scholar 

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Authors
  1. W. Rascher
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Editors and Affiliations

  1. Klinik für Kinder- und Jugendmedizin, Klinikum der Universität Essen (GHS), Hufelandstraße 55, D-45122, Essen, Germany

    H. Stolecke (Ehem. Direktor der Abt. Pädiatrische Endokrinologie) (Ehem. Direktor der Abt. Pädiatrische Endokrinologie)

  2. Postfach 1302, D-49574, Ankum, Germany

    H. Stolecke (Ehem. Direktor der Abt. Pädiatrische Endokrinologie) (Ehem. Direktor der Abt. Pädiatrische Endokrinologie)

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© 1997 Springer-Verlag Berlin Heidelberg

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Rascher, W. (1997). Hormonregulation des Salz- und Wasserhaushalts. In: Stolecke, H. (eds) Endokrinologie des Kindes- und Jugendalters. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59043-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-59043-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-61855-3

  • Online ISBN: 978-3-642-59043-6

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