Abstract
The genus Alkanna (family Boraginaceae) consists of 25 species widely distributed in the Mediterranean regions and Asia. The species Alkanna tinctoria (L.) Taush (2n = 30) also has a wide geographical distribution; in particular, it grows wild in arid maritime areas of southern Europe. The plants are perennial herbs with prostrate bushy stems, blooming between March and May with small (6–7 mm) blue flowers (Fig. 1). The propagation of the plant occurs naturally from seeds that are included in monospermic achenes. The percentage of seed germination is very low, which is true also for other Boraginaceae species (Qi et al. 1993). Alkanna tinctoria has been known since ancient times for the presence in its root of the red pigment alkannin, used since antiquity for its therapeutical properties and as a natural dye.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
De Leo P, Miceli A, Gerardi C (1992) Extraction and purification of alkannin from Alkanna tinctoria Tausch: its location in the plant and time course accumulation in the tissues. Agric Med 122:334–339
De Leo P, Miceli A, Ronzini L, Sgarra R (1996) Chemical characterization of alkannin esterified derivatives. AIHTEI 7:23–25
Fujita Y (1988) Shikonin: production by plant (Lithospermum erythrorhizon) cell cultures. In: Bajaj YPS (ed) Biotechnology in agriculture and forestry, vol 4. Medicinal and aromatic plants 4. Springer, Berlin Heidelberg New York, pp 225–236
Fukui H, Yoshikawa N, Tabata M (1983) Induction of shikonin formation by agar in Lithospermum erythrorhizon cell suspension cultures. Phytochemistry 22:2451–2453
Mita G, Gerardi C, Miceli A, Bollini R, De Leo P (1994) Pigment production from in vitro cultures of Alkanna tinctoria Tausch. Plant Cell Rep 13:406–410
Mizukami H, Konoshima M, Tabata M (1978) Variation in pigment production in Lithospermum erythrorhizon callus cultures. Phytochmistry 17:95–97
Murashige T, Skoog F (1962) A revised medium for rapid growth and bio-assays with tobacco tissue cultures. Physiol Plant 15:473–497
Papageorgiou VP (1978) Wound healing properties of naphthaquinone pigments from Alkanna tinctoria. Experientia 34:1499–1501
Papageorgiou VP, Digenis GA (1980) Isolation of two new alkannin esters from Alkanna tinctoria. Planta Med 39:81–84
Papageorgiou VP, Winkler A, Sagredos AN, Digenis GA (1979) Studies on the relationship of structure to antimicrobial properties of naphthaquinones and other constituents of Alkanna tinctoria. Planta Med 35:56–60
Parr AJ (1989) The production of secondary metabolites by plant cell cultures. J Biotechnol 10:1–26
Qi MQ, Upadhyaya MK, Furness NH, Ellis BE (1993) Mechanism of seed dormancy in Cynoglossum officinale L. J. Plant Physiol 142:325–330
Shimomura K, Sudo H, Sag H, Kamada H (1991) Shikonin production and secretion by hairy root cultures of Lithospermum erythrorhizon. Plant Cell Rep 10:282–285
Tabata M, Fujita Y (1985) Production of shikonin by plant cell cultures. In: Day P, Zaitlin M, Hollander A (eds) Biotechnology in plant science. Academic Press, New York, pp 207–218
Tanaka S, Tajama M, Tsukada M, Tabata M (1986) A comparative study on anti-inflammatory activities of the enantiomers, shikonin and alkannin. J Nat Prod 49:466–469
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Gerardi, C., Mita, G., Grillo, E., Giovinazzo, G., Miceli, A., De Leo, P. (1998). Alkanna tinctoria T. (Alkanets): In Vitro Culture and the Production of Alkannin and Other Secondary Metabolites. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants X. Biotechnology in Agriculture and Forestry, vol 41. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58833-4_2
Download citation
DOI: https://doi.org/10.1007/978-3-642-58833-4_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-63748-3
Online ISBN: 978-3-642-58833-4
eBook Packages: Springer Book Archive