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Antisense Research and Application pp 545–560Cite as

Antisense Properties of Peptide Nucleic Acid

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 131))

Abstract

The hybridization properties of peptide nucleic acid (PNA) combined with its ease of synthesis and high chemical and biological stability rapidly made this molecule a very attractive lead compound for the development of antisense gene therapeutic drugs.

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Authors
  1. P. E. Nielsen
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Editors and Affiliations

  1. ISIS Pharmaceuticals, Inc., Carlsbad Research Center, 2292 Faraday Avenue, Carlsbad, CA, 92008, USA

    Stanley T. Crooke M.D., Ph.D.

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© 1998 Springer-Verlag Berlin Heidelberg

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Nielsen, P.E. (1998). Antisense Properties of Peptide Nucleic Acid. In: Crooke, S.T. (eds) Antisense Research and Application. Handbook of Experimental Pharmacology, vol 131. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58785-6_20

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  • DOI: https://doi.org/10.1007/978-3-642-58785-6_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63730-8

  • Online ISBN: 978-3-642-58785-6

  • eBook Packages: Springer Book Archive

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