Skip to main content

Ovarielle Stimulation: Möglichkeiten und Komplikationen

  • Chapter
Weibliche Sterilität
  • 66 Accesses

Zusammenfassung

Ovarielle Funktionsstörungen, die mit einer Anovulation einhergehen, machen ca. 35–40% der Ursachen einer bestehenden Ehesterilität aus. Folgerichtig stehen sie im Vordergrund der Sterilitätsbehandlung. Klinisch können sich diese Störungen in einer Vielzahl von Symptomen äußern. Diese reichen von der einfachen Regeltempostörung über die Oligomenorrhö bis zur primären oder sekundären Amenorrhö, zum Teil einhergehend mit weiteren Symptomen (s. Übersicht).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Adashi EY (1990) Ovulation induction:Comiphene citrate. In: Seibel MM (ed) Infertility:a comprehensive text. Appleton & Lange, Norwalk/CT

    Google Scholar 

  • Adashi EY (1994) Clomiphene citrate. In: Seibel MM, Blackwell RE (eds) Ovulation induction. Raven, New York, pp. 95

    Google Scholar 

  • Ash RH, Greenblatt RB (1976) Update on the safety and efficacy of clomiphene citrate as a therapeutic agent. J Reprod Med 17:175

    Google Scholar 

  • Ash R, Irvey G, Goldsman M, Frederick JL, Stone SC, Balmaceda JP (1994) The use of intravenous albumin in patients at high risk for severe ovarian hyperstimulation syndrome. Hum Reprod 8:1015

    Google Scholar 

  • Bauer O, Diedrich K (1996) Komplikationen der assistierten Reproduktion. Gynäkologe 29:464

    Article  Google Scholar 

  • Baumann P, Felberbaum R, Diedrich K (1996) Schwangerschaft and Geburt nach In-vitroFertilisation. Gynäkologe 29:507

    Article  Google Scholar 

  • Boue JG, Boue A (1973) Increased frequency of chromosomal anomalies in abortions after induced ovulation. Lancet I-679

    Google Scholar 

  • Chappal S, Kelton C, Nugent N (1992) Expression of human gonadotropins by recombinant DNA methods. In: Genazzi A, Petraglia F (eds) Proceedings of the 3rd World Congress on Gynecological Endocrinology. Parthenon, Camforth, pp 179

    Google Scholar 

  • Daya S (1995) Menopausal gonadotrophin for in vitro fertilization; results of a metaanalysis. Horm Res 43:224

    Article  PubMed  CAS  Google Scholar 

  • De Geyter C, De Geyter M, Castro E, Bals-Pratsch M, Nieschlag E, Schneider HPG (1996) Experience with transvaginal ultrasound-guided aspiration of supernumerary follicles for the prevention of multiple pregnancies after ovulation induction and intrauterine insemination. Fertil Steril 65:1163

    PubMed  Google Scholar 

  • Dekel N (1988) Spatial relationship of follicular cells in the control of meiosis. In: Haseltine FP, First NL (eds) Progress in clinical and biological research. Meiotic inhibition:molecular control of meiosis. Liss, New York

    Google Scholar 

  • Delbaere A, Bergmann PJM, Gervy-Decoster C, Staroukine M, Englert Y (1994) Angiotensin II immunoreactivity is elevated in ascites during severe ovarian hyperstimulation syndrome; implications for pathophysiology and clinical management. Fertil Steril 62:731–737

    PubMed  CAS  Google Scholar 

  • Diedrich K (1990) In-Vitro-Fertilisation and Embryotransfer. Gegenwärtiger Stand. Fertilität 3:93

    Google Scholar 

  • Diedrich K, Diedrich C, Santos E et al. (1994) Suppression of the endogenous luteinizing hormone surge by the gonadotropin-releasing hormone antagonist Cetrorelix during ovarian stimulation. Hum Reprod 9:788

    PubMed  CAS  Google Scholar 

  • Diedrich K, Felberbaum R, Baumann P (1996) Assistierte Reproduktion-ein Überblick. Gynäkolog 29:413

    Article  Google Scholar 

  • Dufau HL, Catt RJ, Tsuruhara T (1971) Retention of in vitro biological activities by desialytated human luteinizing hormone and chorionic gonadotropin. Biochem Biophys Res Commun 44:1022

    Article  PubMed  CAS  Google Scholar 

  • Edwards RG, Lobo R, Bouchard P (1996) Time to revolutionize ovarian stimulation. Hum Reprod 11:917

    Article  PubMed  CAS  Google Scholar 

  • Felberbaum R, Diedrich K (1996) Klinischer Einsatz der GnRH-Analoga im Rahmen der Sterilitätstherapie:Agonisten und Antagonisten. Gynäkologe 29:420

    Article  Google Scholar 

  • Felberbaum R, Küpker W, Neulen J, Diedrich K (1996) Einsatz des rekombinanten humanen follikelstimulierenden Hormons (rec.FSH) in der Sterilitätstherapie:Informationen für die Praxis. Frauenarzt 37:1192

    Google Scholar 

  • Fernandez L, Twickler J, Mead A (1985) Neovascularization produced by angiotensin II. J Lab Clin Med 105:219–223

    Google Scholar 

  • Golan A, Ron-El R, Herman A, Weintraub Z, Soffer Y, Caspi E (1989) Ovarian hyperstimulation syndrome:an update review. Obstet Gynecol Sury 44:430–440

    Article  CAS  Google Scholar 

  • Greenblatt RB, Barfield WE, Jungck EC, Ray AW (1961) Induction of ovulation with MAL/ 41. JAMA 178:101

    Article  PubMed  CAS  Google Scholar 

  • Hassiakos D, Toner JP, Muasher SJ, Jones HW Jr (1990) Implantation and pregnancy rats in relation to oestradiol and progesterone profiles in cycles with and without the use of gonadotrophin-releasing hormone agonist suppression. Hum Reprod 5:1004

    PubMed  CAS  Google Scholar 

  • Hoff YD, Quigley ME, Yen SCC (1983) Hormonal dynamics at midcycle:a reevaluation. J Clin Endocrinol Metab 57:892–896

    Article  Google Scholar 

  • Hoffmann D, Lobo RA (1985) Serum dehydroepiandrosterone sulfate and the use of clomiphene citrate in anovulatory women. Fertil Steril 43:196

    Google Scholar 

  • Homburg R, Giroud D, Howles C, Loumaye E (1995) Efficacy of recombinant human follicle hormone Gonal-F for inducing ovulation in WHO II group anovulatory patients. Preliminary results of a comparative multicentre study. Front Endocrinol 4:463

    Google Scholar 

  • Howles CM, Macnamee MC, Edwards RG, Goswamy R, Steptoe PC (1986) Effect of high tonic levels of luteinizing hormone on outcome of in-vitro fertilization. Lancet II:521–522

    Article  Google Scholar 

  • Kleinstein J (1991) Das Hyperstimulationssyndrom. Gynäkologe 24:130–135

    PubMed  CAS  Google Scholar 

  • Lehmann F, Breckwoldt M (1991) Gonadotropine:drei Jahrzehnte Entwicklung. HMG-Behandlung in der Praxis. Enke, Stuttgart ( Bücherei des Frauenarztes, Bd. 39 )

    Google Scholar 

  • Lemay A, Maheux R, Faure N, Jean C, Fazekas ATA (1984) Reversible hypogonadism induced by a luteinizing hormone-releasing hormone (LH-RH) agonist (Buserelin) as a new therapeutic approach for endometriosis. Fertil Steril 41:863

    PubMed  CAS  Google Scholar 

  • Loumaye E, Campbell R, Salat-Baroux J (1995) Human follicle-stimulating hormone produced by recombinant DNA technology:a review for clinicians. Hum Reprod Update 1:188

    Article  PubMed  CAS  Google Scholar 

  • Lunenfeld B, Blankstein J, Ron-El R (1987) Short and long term survey of patients treated with HMG/HCG and follow-up of offspring. In: Genazziani AR, Volpe A, Fachinetti F (eds) Proceedings of the first international congress on gynecological endocrinology, p 459

    Google Scholar 

  • Lunenfeld B, Insler V, Glezerman M (1992) Diagnosis and treatment of functional infertility. Blackwell, Berlin

    Google Scholar 

  • Navot D, Margalioth EJ, Laufer N, Birkenfeld A, Relou A, Schenker JG (1987) Direct correlation between plasma renin activity and severity of the ovarian hyperstimulation syndrome. Fertil Steril 48:57–61

    PubMed  CAS  Google Scholar 

  • Olivennes F, Rufat P, Andrè B, Pourade A, Quiros MC, Frydman R (1993) Increased risk of complication observed in singleton pregnancies resulting from in-vitro-fertilization (IVF) does not seem to be related to the IVF method itself. Hum Reprod 8:1297

    PubMed  CAS  Google Scholar 

  • Palopoli FP, Feil VJ, Allen RE, Holtkamp DE, Richardson A Jr (1967) Substituted aminoalkoxytriarylhaloethylenes. J Med Chem 10:84

    Article  PubMed  CAS  Google Scholar 

  • Shoham Z (1993) Low-dose protocol of follicle stimulating hormone for induction of ovulation in patients with polycystic ovary syndrome:the hypothesis, etiology and clinical experience. In: Lunenfeld B (ed) FSH alone in ovulation induction. Parthenon, New York, pp 29

    Google Scholar 

  • Shoham Z, Zosmer A, Insler V (1991) Early miscarriage and fetal malformations after induction of ovulation (by clomiphene citrate and/or human menotropins), in vitro fertilization and gamete intrafallopian transfer. Fertil Steril 55:1

    PubMed  CAS  Google Scholar 

  • Smitz J, Devroey P, Faguer B, Bourgain C, Camus M, Van Steirteghem AC (1992) A prospective randomized comparison of intramuscular or intravaginal natural progesterone as a luteal phase and early pregnancy supplement. Hum Reprod 7:168–175

    Article  PubMed  CAS  Google Scholar 

  • Stanger JD, Yovich JL (1985) Reduced in vitro fertilization of human oocytes from patients with raised basal luteinizing hormone levels during the follicular phase. BJ Obstet Gynaecol 92:385–393

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Felberbaum, R., Ortmann, O., Weiss, J., Diedrich, K. (1998). Ovarielle Stimulation: Möglichkeiten und Komplikationen. In: Diedrich, K. (eds) Weibliche Sterilität. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58738-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-58738-2_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63704-9

  • Online ISBN: 978-3-642-58738-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics